Enalaprilat
- Generic Name
- Enalaprilat
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C18H24N2O5
- CAS Number
- 76420-72-9
- Unique Ingredient Identifier
- Q508Q118JM
- Background
Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of th...
- Indication
Enalaprilat injection is indicated for the treatment of hypertension when oral therapy is not practical.
- Associated Conditions
- Diabetic Nephropathy, Heart Failure, Hypertension, Left Ventricular Dysfunction
- Associated Therapies
- -
Effect of DPP4 Inhibition on Vasoconstriction
- Conditions
- Interventions
- First Posted Date
- 2015-12-24
- Last Posted Date
- 2018-08-27
- Lead Sponsor
- Vanderbilt University
- Target Recruit Count
- 18
- Registration Number
- NCT02639637
- Locations
- 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States
The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow Distribution
- First Posted Date
- 2008-08-26
- Last Posted Date
- 2015-12-18
- Lead Sponsor
- The Hospital for Sick Children
- Target Recruit Count
- 12
- Registration Number
- NCT00741156
- Locations
- 🇨🇦
The Hospital for Sick Children, Toronto, Ontario, Canada
Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage
- Conditions
- First Posted Date
- 2005-09-26
- Last Posted Date
- 2008-06-26
- Lead Sponsor
- The George Institute
- Target Recruit Count
- 404
- Registration Number
- NCT00226096
- Locations
- 🇦🇺
Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
🇦🇺Royal Adelaide Hospital, Adelaide, South Australia, Australia
🇦🇺Royal Melbourne Hospital, Melbourne, Victoria, Australia
Drug Development Updates
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