Minoxidil

Generic Name: Minoxidil

Brand Names: Loniten, Minox, Regoxidine, Rogaine

Drug Type: Small Molecule

Chemical Formula: C_₉H_₁₅N_₅O

CAS Number: 38304-91-5

Unique Ingredient Identifier: 5965120SH1

Background: A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.

Indication: For the treatment of severe hypertension and in the topical treatment (regrowth) of androgenic alopecia in males and females and stabilisation of hair loss in patients with androgenic alopecia.

Associated Conditions: Androgenetic Alopecia (AGA), Severe, symptomatic Hypertension

Clinical Trials

Evaluating the Topical Herbal Solution on the Treatment of Male Pattern Hair Loss and Comparison With Minoxidil 5%

Phase 3

Completed

Conditions: Androgenetic Alopecia

Interventions: Drug: Topical Herbal Solution
Drug: Topical Minoxidil 5%

First Posted Date: 2018-11-26

Last Posted Date: 2020-03-16

Lead Sponsor: Farid Masoud

Target Recruit Count: 24

Registration Number: NCT03753113

Locations: 🇮🇷
Department of Dermatology, Sina Hospital, Tabriz, East Azerbaijan, Iran, Islamic Republic of

Topical 5% Minoxidil and Potent Topical Corticosteroid Versus Intralesional Corticosteroid in the Treatment of Alopecia Areata

Phase 4

Completed

Conditions: Alopecia Areata

Interventions: Drug: Minoxidil 5 % Topical Spray
Drug: Triamcinolone Acetonide
Drug: clobetasol propionate

First Posted Date: 2018-05-24

Last Posted Date: 2018-05-24

Lead Sponsor: Cairo University

Target Recruit Count: 40

Registration Number: NCT03535233

Topical Minoxidil Versus Topical Glyceryl Trinitrate in Treatment of Chronic Anal Fissure

Not Applicable

Completed

Conditions: Anal Fissure

Interventions: Drug: Minoxidil
Drug: Glyceryl trinitrate

First Posted Date: 2018-05-18

Last Posted Date: 2019-10-07

Lead Sponsor: Mansoura University

Target Recruit Count: 62

Registration Number: NCT03528772

Locations: 🇪🇬
Mansoura university hospital, Mansourah, Dakahlia, Egypt

Platelet Rich Plasma Versus Minoxidil Foam for Treatment of Androgenic Alopecia in Women

Phase 1

Completed

Conditions: Alopecia

Interventions: Other: Platelet Rich Plasma
Drug: Minoxidil Foam

First Posted Date: 2018-04-04

Last Posted Date: 2020-04-08

Lead Sponsor: Mayo Clinic

Target Recruit Count: 20

Registration Number: NCT03488108

Locations: 🇺🇸
Mayo Clinic Florida, Jacksonville, Florida, United States

ENERGI-F701 for Female Hair Loss Treatment

Phase 2

Completed

Conditions: Hair Loss
Female Pattern Baldness
Alopecia

Interventions: Drug: ENERGI-F701
Drug: Regaine

First Posted Date: 2017-11-22

Last Posted Date: 2020-11-24

Lead Sponsor: Energenesis Biomedical Co., Ltd.

Target Recruit Count: 67

Registration Number: NCT03351322

Locations: 🇨🇳
Taipei Veterans General Hospital, Taipei, Taiwan

The Use of 5mg Finasteride Versus 200mg Spironolactone and Topical 5% Minoxidil in Treating Postmenopausal Female Androgenetic Alopecia

Phase 4

Withdrawn

Conditions: Female Androgenetic Alopecia

Interventions: Drug: 5% Minoxidil
Drug: 5mg Finasteride
Drug: 200mg Spironolactone
Other: Placebo

First Posted Date: 2015-06-26

Last Posted Date: 2016-09-02

Lead Sponsor: University of Florida

Registration Number: NCT02483195

Locations: 🇺🇸
UF Health, Gainesville, Florida, United States

Clinical Trial to Explore the Efficacy and Safety of DA-4001 After Topical Application

Phase 1

Completed

Conditions: Androgenetic Alopecia

Interventions: Drug: DA-4001C
Drug: 5% minoxidil

First Posted Date: 2014-10-31

Last Posted Date: 2015-06-24

Lead Sponsor: Dong-A ST Co., Ltd.

Target Recruit Count: 60

Registration Number: NCT02280603

Locations: 🇰🇷
Catholic Medical Center, Seoul, Dongdaemun-gu, Korea, Republic of

A Phase 2 Study to Evaluate the Safety and Efficacy of CB-03-01 Solution, a Comparator Solution and Vehicle Solution in Males With Androgenetic Alopecia

Phase 2

Completed

Conditions: Androgenetic Alopecia

Interventions: Drug: Minoxidil Solution 5%
Drug: Placebo solution
Drug: CB-03-01 solution

First Posted Date: 2014-10-31

Last Posted Date: 2017-03-13

Lead Sponsor: Intrepid Therapeutics, Inc.

Target Recruit Count: 95

Registration Number: NCT02279823

Locations: 🇺🇸
DermResearch, Inc., Austin, Texas, United States
🇺🇸
Therapeutics Clinical Research, San Diego, California, United States
🇺🇸
Minnesota Clinical Study Center, Fridley, Minnesota, United States

Minoxidil Response Testing in Females With Female Pattern Hair Loss

Completed

Conditions: Alopecia
Female Pattern Hair Loss

Interventions: Drug: 5% minoxidil topical foam

First Posted Date: 2014-08-01

Last Posted Date: 2018-10-05

Lead Sponsor: Applied Biology, Inc.

Target Recruit Count: 300

Registration Number: NCT02206802

Locations: 🇮🇳
LTM Medical College & Hospital, Mumbai, India
🇦🇺
Sinclair Dermatology, East Melbourne, Australia
🇮🇹
Istituto Medico Tricologico/Studi Life Cronos, Florence, Italy

and more 2 locations

Minoxidil Response Testing in Males With Androgenetic Alopecia

Completed

Conditions: Androgenetic Alopecia

Interventions: Drug: 5% minoxidil topical foam

First Posted Date: 2014-07-23

Last Posted Date: 2018-10-05

Lead Sponsor: Applied Biology, Inc.

Target Recruit Count: 300

Registration Number: NCT02198261

Locations: 🇺🇸
Tennessee Clinical Research Center, Nashville, Tennessee, United States
🇺🇸
Physicians Hair Institute, Tucson, Arizona, United States
🇮🇹
Istituto Medico Tricologico/Studi Life Cronos, Florence, Italy

and more 2 locations

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

Home Terms & Conditions Privacy Policy