MedPath

NuCana

NuCana logo
🇬🇧United Kingdom
Ownership
Public
Established
1997-01-01
Employees
28
Market Cap
-
Website
http://www.nucana.com
Introduction

NuCana Plc is a clinical stage biopharmaceutical company. It engages in the business of developing a portfolio of new medicines to treat patients with cancer. The company was founded by Hugh Stephen Griffith and Christopher Barry Wood on January 28, 1997 and is headquartered in Edinburgh, the United Kingdom.

Clinical Trials

6

Active:1
Completed:1

Trial Phases

3 Phases

Phase 1:3
Phase 2:2
Phase 3:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (6 trials with phase data)• Click on a phase to view related trials

Phase 1
3 (50.0%)
Phase 2
2 (33.3%)
Phase 3
1 (16.7%)

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

Phase 1
Terminated
Conditions
Advanced Cancer
Advanced Solid Tumor
Neoplasm Malignant
Metastatic Cancer
Melanoma
Classical Hodgkin Lymphoma
Non Small Cell Lung Cancer
Renal Cell Carcinoma
Urothelial Carcinoma
Head and Neck Squamous Cell Carcinoma
Interventions
First Posted Date
2023-02-06
Last Posted Date
2025-07-18
Lead Sponsor
NuCana plc
Target Recruit Count
19
Registration Number
NCT05714553
Locations
🇬🇧

Queen Elizabeth Hospital University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom

🇬🇧

The Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom

🇬🇧

Guy's and St Thomas NHS Foundation Trust, London, United Kingdom

and more 1 locations

A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

Phase 2
Active, not recruiting
Conditions
Colorectal Cancer Metastatic
Neoplasm, Colorectal
Colorectal Adenocarcinoma
Colorectal Cancer
Colorectal Neoplasms
Interventions
First Posted Date
2023-01-10
Last Posted Date
2024-04-03
Lead Sponsor
NuCana plc
Target Recruit Count
182
Registration Number
NCT05678257
Locations
🇺🇸

Helen F. Graham Cancer Center, Newark, Delaware, United States

🇺🇸

Georgetown University Medical Center, Washington, District of Columbia, United States

🇺🇸

University of Florida Health Medical Oncology - Davis Cancer Pavilion, Gainesville, Florida, United States

and more 56 locations

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Phase 3
Terminated
Conditions
Biliary Tract Cancer
Interventions
First Posted Date
2019-11-15
Last Posted Date
2023-05-24
Lead Sponsor
NuCana plc
Target Recruit Count
773
Registration Number
NCT04163900
Locations
🇺🇸

Arizona Oncology Associates , PC - HOPE, Tucson, Arizona, United States

🇺🇸

University of Arizona Cancer Center, Tucson, Arizona, United States

🇺🇸

The Oncology Institute of Hope and Innovation, Whittier, California, United States

and more 122 locations

A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma

Phase 1
Recruiting
Conditions
Advanced Cancer
Solid Tumor
Lymphoma
Interventions
First Posted Date
2019-02-04
Last Posted Date
2024-11-11
Lead Sponsor
NuCana plc
Target Recruit Count
135
Registration Number
NCT03829254
Locations
🇬🇧

University of Edinburgh, Edinburgh, United Kingdom

🇬🇧

The Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom

🇬🇧

The Christie NHS Foundation Trust, Manchester, United Kingdom

and more 2 locations

A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment

Phase 1
Completed
Conditions
Neoplasms, Colorectal
Colorectal Carcinoma
Colorectal Neoplasms
Colorectal Tumors
Colorectal Cancer
Interventions
Drug: NUFIRI
Drug: NUFOX + VEGF pathway inhibitor
Drug: NUFOX
Drug: NUFIRI + VEGF pathway inhibitor
Drug: NUFIRI + EGFR inhibitor
Drug: NUC-3373 + bevacizumab
Drug: NUFOX + EGFR inhibitor
First Posted Date
2018-02-12
Last Posted Date
2025-04-23
Lead Sponsor
NuCana plc
Target Recruit Count
111
Registration Number
NCT03428958
Locations
🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

and more 7 locations
  • Prev
  • 1
  • 2
  • Next

News

No news found

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.