VANDERBILT UNIVERSITY MEDICAL CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private, Subsidiary

Established: 1925-01-01

Employees: 10K

Market Cap: -

Website: http://www.vumc.org

Clinical Trials

Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty

Phase 4

Recruiting

Conditions: Osteoarthritis, Knee
Chronic Postsurgical Pain
Total Knee Arthroplasty

Interventions: Drug: GlyNAC (combination of glycine and n-acetylcysteine)
Drug: Placebo

First Posted Date: 2023-10-16

Last Posted Date: 2024-12-12

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 148

Registration Number: NCT06083480

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Home-Based Cardiac Rehabilitation Using a Novel Mobile Health Exercise Regimen Following Transcatheter Heart Valve Interventions

Not Applicable

Recruiting

Conditions: Valvular Heart Disease

Interventions: Other: HBCR interactive
Other: HBCR hands-off

First Posted Date: 2023-10-11

Last Posted Date: 2024-06-18

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 375

Registration Number: NCT06077201

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Effect of Direct-from-blood Bacterial Testing on Antibiotic Administration and Clinical Outcomes

Not Applicable

Active, not recruiting

Conditions: Vancomycin
Bloodstream Infection
Sepsis Bacterial
MRSA Bacteremia

Interventions: Other: Usual Care
Other: T2Bacteria® Panel (direct-from-blood testing)

First Posted Date: 2023-10-05

Last Posted Date: 2024-12-13

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 500

Registration Number: NCT06069206

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Tranexamic Acid in Nasal Mohs Reconstruction

Phase 2

Recruiting

Conditions: Skin Cancer Face
Postoperative Bleeding

First Posted Date: 2023-09-28

Last Posted Date: 2024-05-13

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 100

Registration Number: NCT06057675

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Improving CarE for Community Acquired Pneumonia 1 (ICE-CAP2)

Not Applicable

Completed

Conditions: Pneumonia Childhood

Interventions: Behavioral: Clinical Decision Support

First Posted Date: 2023-09-13

Last Posted Date: 2023-12-05

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 536

Registration Number: NCT06033079

Locations: 🇺🇸
Monroe Carell Jr. Children's Hospital - Vanderbilt University Medical Center, Nashville, Tennessee, United States

Long COVID Immune Profiling

Not Applicable

Recruiting

Conditions: POTS - Postural Orthostatic Tachycardia Syndrome
Autonomic Dysfunction
Long COVID

Interventions: Diagnostic Test: IL-6
Diagnostic Test: cytokines (IL-17, and IFN-ɣ)
Behavioral: Compass 31

First Posted Date: 2023-09-07

Last Posted Date: 2024-06-11

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 150

Registration Number: NCT06027255

Locations: 🇺🇸
Cyndya Shibao, Nashville, Tennessee, United States

Use of MRI and CTBS for Catatonia in Autism

Phase 1

Recruiting

Conditions: Autism Spectrum Disorder
Catatonia
Intellectual Disability

Interventions: Device: Continuous Theta Burst in Transcranial Magnetic Stimulation

First Posted Date: 2023-08-30

Last Posted Date: 2025-01-09

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 40

Registration Number: NCT06016764

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated with Radioactive Iodine for Thyroid Cancer

Phase 3

Recruiting

Conditions: Nasolacrimal Duct Obstruction
Thyroid Cancer

Interventions: Drug: Artificial Tears Methylcellulose

First Posted Date: 2023-08-21

Last Posted Date: 2024-10-26

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 100

Registration Number: NCT05999630

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Attentional Mechanisms in SCD

Early Phase 1

Not yet recruiting

Conditions: Subjective Cognitive Decline

Interventions: Drug: Mecamylamine Challenge
Other: Placebo Comparator Challenge

First Posted Date: 2023-08-21

Last Posted Date: 2024-12-17

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 80

Registration Number: NCT06002477

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Low-dose Buccal Buprenorphine: Relative Abuse Potential and Analgesia

Phase 4

Recruiting

Conditions: Pain
Analgesia
Abuse Opioids

Interventions: Drug: Buccal Placebo
Drug: Buccal Buprenorphine 300 mcg
Drug: Buccal Buprenorphine 600 mcg
Drug: Buccal Buprenorphine 900 mcg
Drug: Oral Placebo
Drug: Buccal Buprenorphine 450mcg
Drug: Oral immediate-release oxycodone 10mg

First Posted Date: 2023-08-14

Last Posted Date: 2024-12-12

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 72

Registration Number: NCT05988710

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

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