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NEUROCRINE BIOSCIENCES, INC.

NEUROCRINE BIOSCIENCES, INC. logo
🇸🇪Sweden
Ownership
Public
Established
1992-01-01
Employees
1.4K
Market Cap
$15.4B
Website
http://www.neurocrine.com

Clinical Trials

79

Active:5
Completed:52

Trial Phases

5 Phases

Phase 1:21
Phase 2:31
Phase 3:18
+2 more phases

Drug Approvals

2

FDA:2

Drug Approvals

INGREZZA

Approval Date
Aug 18, 2023
FDA

ONGENTYS

Approval Date
Apr 26, 2020
FDA

Clinical Trials

Distribution across different clinical trial phases (76 trials with phase data)• Click on a phase to view related trials

Phase 2
31 (40.8%)
Phase 1
21 (27.6%)
Phase 3
18 (23.7%)
Not Applicable
3 (3.9%)
Phase 4
3 (3.9%)

NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia

Not Applicable
Recruiting
Conditions
Schizophrenia
Interventions
First Posted Date
2025-08-11
Last Posted Date
2025-08-11
Lead Sponsor
Neurocrine Biosciences
Target Recruit Count
800
Registration Number
NCT07114874
Locations
🇺🇸

Neurocrine Clinical Site, San Diego, California, United States

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

Not Applicable
Not yet recruiting
Conditions
Schizophrenia
Schizoaffective Disorder
Bipolar Disorder
Major Depressive Disorder
Tardive Dyskinesia
Interventions
First Posted Date
2025-08-05
Last Posted Date
2025-08-05
Lead Sponsor
Neurocrine Biosciences
Target Recruit Count
50
Registration Number
NCT07105111

NBI-1117568-SCZ3030: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia

Not Applicable
Not yet recruiting
Conditions
Schizophrenia
Interventions
Drug: Placebo
First Posted Date
2025-08-05
Last Posted Date
2025-08-05
Lead Sponsor
Neurocrine Biosciences
Target Recruit Count
284
Registration Number
NCT07105098

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Phase 3
Recruiting
Conditions
Major Depressive Disorder
Interventions
First Posted Date
2025-05-11
Last Posted Date
2025-08-01
Lead Sponsor
Neurocrine Biosciences
Target Recruit Count
600
Registration Number
NCT06966401
Locations
🇺🇸

Neurocrine Clinical Site, Everett, Washington, United States

NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia

Phase 3
Recruiting
Conditions
Schizophrenia
Interventions
Drug: Placebo
First Posted Date
2025-05-08
Last Posted Date
2025-07-30
Lead Sponsor
Neurocrine Biosciences
Target Recruit Count
284
Registration Number
NCT06963034
Locations
🇺🇸

Neurocrine Clinical Site, Austin, Texas, United States

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News

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Neurocrine Biosciences Advances CAH Treatment Portfolio with Long-Acting Injectable Therapy

Neurocrine Biosciences initiated Phase 1 trials for NBIP-01435, a long-acting injectable CRF1 receptor antagonist for congenital adrenal hyperplasia (CAH), complementing its recently approved oral therapy CRENESSITY.

Neurocrine Biosciences Initiates Phase 1 Trial for Long-Acting CAH Treatment NBIP-01435

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AbbVie Sues Hetero Labs Over New Orilissa Patent to Block Generic Endometriosis Drug

AbbVie has filed a new patent infringement lawsuit against Hetero Labs to prevent the production of generic versions of its endometriosis drug Orilissa (elagolix sodium).

Voyager Therapeutics Publishes Breakthrough Research on ALPL-Mediated Blood-Brain Barrier Transport for Gene Therapy

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Biopharma Q1 Updates: New Drug Launches and FDA Extension for Cytokinetics' Aficamten

Neurocrine Biosciences, Madrigal Pharmaceuticals, and Vanda Therapeutics provided investors with key updates on their recent drug launches during Q1 earnings calls.

Crinecerfont Shows Promise in Pediatric Congenital Adrenal Hyperplasia Across All Patient Subgroups

Phase 3 CAHtalyst pediatric study demonstrates that crinecerfont (CRENESSITY) effectively reduces glucocorticoid dosing while maintaining or improving androstenedione levels in children with classic congenital adrenal hyperplasia.

CRENESSITY Shows Consistent Efficacy Across Pediatric CAH Subgroups While Reducing Glucocorticoid Doses

New analyses from Neurocrine Biosciences' Phase 3 CAHtalyst Pediatric study demonstrate CRENESSITY (crinecerfont) consistently reduced glucocorticoid doses while maintaining or improving androstenedione levels across all patient subgroups.

Neurocrine Biosciences Advances Novel Muscarinic M4 Agonist to Phase 3 Trials for Schizophrenia

Neurocrine Biosciences has initiated a Phase 3 registrational program for NBI-1117568, an oral muscarinic M4 selective orthosteric agonist, following positive Phase 2 results in schizophrenia patients.

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