MedPath

Incyte

🇺🇸United States
Ownership
-
Employees
2.5K
Market Cap
$12.6B
Website
Introduction

Incyte Corp. is a biopharmaceutical company, which engages in the discovery, development, and commercialization of proprietary therapeutics. It focuses on hematology and oncology, and inflammation and autoimmunity therapeutic areas. The company was founded in April 1991 and is headquartered in Wilmington, DE.

Efficacy and Safety of Pemigatinib in Subjects With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma Who Failed Previous Therapy - (FIGHT-202)

Phase 2
Completed
Conditions
Cholangiocarcinoma
Interventions
First Posted Date
2016-10-05
Last Posted Date
2023-02-23
Lead Sponsor
Incyte Corporation
Target Recruit Count
147
Registration Number
NCT02924376

An Open-Label Phase 1/2 Study of Itacitinib in Combination With Osimertinib in Subjects With Non-Small Cell Lung Cancer

Phase 1
Active, not recruiting
Conditions
Lung Cancer
Interventions
First Posted Date
2016-09-28
Last Posted Date
2025-04-24
Lead Sponsor
Incyte Corporation
Target Recruit Count
59
Registration Number
NCT02917993
Locations
🇺🇸

Valley Hospital, 223 N Van Dien Avenue, Ridgewood, New Jersey, United States

🇺🇸

West Virginia University Cancer Institute, 1 Medical Center Drive, Morgantown, West Virginia, United States

🇺🇸

University of Texas -MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, Texas, United States

and more 28 locations

Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors

Phase 1
Completed
Conditions
Lung Cancer
Renal Cell Carcinoma (RCC)
Mesothelioma
Metastatic Cancer
Solid Tumors
Colorectal Cancer (CRC)
Bladder Cancer
UC (Urothelial Cancer)
Gastric Cancer
Head and Neck Cancer
Interventions
First Posted Date
2016-09-16
Last Posted Date
2023-02-24
Lead Sponsor
Incyte Corporation
Target Recruit Count
260
Registration Number
NCT02903914
Locations
🇺🇸

Johns Hopkins, Baltimore, Maryland, United States

🇺🇸

BIDMC, Boston, Massachusetts, United States

🇺🇸

MD Anderson, Houston, Texas, United States

and more 16 locations

A Study to Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) in Subjects With Urothelial Carcinoma - (FIGHT-201)

Phase 2
Completed
Conditions
UC (Urothelial Cancer)
Interventions
First Posted Date
2016-08-19
Last Posted Date
2023-03-24
Lead Sponsor
Incyte Corporation
Target Recruit Count
263
Registration Number
NCT02872714
Locations
🇩🇪

Klinikum Dresden Standort Dresden-Friedrichstadt, Dresden, Germany

🇩🇪

Universitaetsklinikum Carl Gustav Carus TU Dresden, Dresden, Germany

🇩🇪

Universitaetsklinikum Hamburg-Eppendorf, Hamburg, Germany

and more 93 locations

A Trial to Evaluate the Efficacy and Safety of Tafasitamab With Bendamustine (BEN) Versus Rituximab (RTX) With BEN in Adult Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Phase 2
Completed
Conditions
Diffuse Large B-cell Lymphoma
Interventions
First Posted Date
2016-05-05
Last Posted Date
2025-04-04
Lead Sponsor
Incyte Corporation
Target Recruit Count
450
Registration Number
NCT02763319
Locations
🇬🇧

MorphoSys Research Site, Southend on Sea, United Kingdom

🇬🇧

Morphosys Research Site, Birmingham, United Kingdom

🇨🇿

Morphosys Research site, Olomouc, Czechia

and more 2 locations

A Study of Itacitinib (INCB039110) in Combination With Ibrutinib in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Phase 1
Completed
Conditions
Lymphoma
Interventions
First Posted Date
2016-05-03
Last Posted Date
2023-06-15
Lead Sponsor
Incyte Corporation
Target Recruit Count
33
Registration Number
NCT02760485
Locations
🇺🇸

LAC-USC Medical Center/Kenneth Norris Jr Cancer Hospital, Los Angeles, California, United States

🇺🇸

Pacific Shores Medical Group, Long Beach, California, United States

🇺🇸

Mayo Clinic Arizona, Scottsdale, Arizona, United States

and more 18 locations

A Phase 3 Study of Pembrolizumab + Epacadostat or Placebo in Subjects With Unresectable or Metastatic Melanoma (Keynote-252 / ECHO-301)

Phase 3
Completed
Conditions
Melanoma
Interventions
First Posted Date
2016-04-26
Last Posted Date
2020-08-27
Lead Sponsor
Incyte Corporation
Target Recruit Count
706
Registration Number
NCT02752074

A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia

First Posted Date
2016-03-31
Last Posted Date
2025-05-02
Lead Sponsor
Incyte Corporation
Target Recruit Count
171
Registration Number
NCT02723994
Locations
🇺🇸

Sinai Hospital of Baltimore, Baltimore, Maryland, United States

🇺🇸

Childrens Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States

🇺🇸

Texas Childrens Hospital, Houston, Texas, United States

and more 105 locations

A Study of INCB050465 in Combination With Ruxolitinib in Subjects With Myelofibrosis

Phase 2
Terminated
Conditions
MPN (Myeloproliferative Neoplasms)
Interventions
First Posted Date
2016-03-24
Last Posted Date
2024-05-01
Lead Sponsor
Incyte Corporation
Target Recruit Count
74
Registration Number
NCT02718300
Locations
🇺🇸

California Cancer Associates For Research and Excellence, Fresno, California, United States

🇺🇸

Baylor Scott and White Research Institute, Dallas, Texas, United States

🇺🇸

University of Chicago Medical Center, Chicago, Illinois, United States

and more 36 locations

An Open-Label, Dose-Escalation/Dose-Expansion Safety Study of INCB059872 in Subjects With Advanced Malignancies

Phase 1
Terminated
Conditions
Solid Tumors and Hematologic Malignancy
Interventions
Drug: all-trans retinoic acid (ATRA)
First Posted Date
2016-03-18
Last Posted Date
2023-06-12
Lead Sponsor
Incyte Corporation
Target Recruit Count
116
Registration Number
NCT02712905
Locations
🇺🇸

Northwestern University, Chicago, Illinois, United States

🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

🇺🇸

University of Kansas Center for Research, Inc., Kansas City, Kansas, United States

and more 12 locations
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