MedPath

Incyte

🇺🇸United States
Ownership
-
Employees
2.5K
Market Cap
$12.6B
Website
Introduction

Incyte Corp. is a biopharmaceutical company, which engages in the discovery, development, and commercialization of proprietary therapeutics. It focuses on hematology and oncology, and inflammation and autoimmunity therapeutic areas. The company was founded in April 1991 and is headquartered in Wilmington, DE.

Study of the JAK Inhibitor Ruxolitinib Administered Orally to Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera-Myelofibrosis (PPV-MF) or Post-Essential Thrombocythemia-Myelofibrosis (PET-MF)

Phase 1
Completed
Conditions
Myelofibrosis
Interventions
First Posted Date
2011-03-17
Last Posted Date
2022-03-09
Lead Sponsor
Incyte Corporation
Target Recruit Count
69
Registration Number
NCT01317875

Safety and Efficacy of INCB007839 With Trastuzumab and Vinorelbine in Patients With Metastatic HER2+ Breast Cancer

Phase 1
Terminated
Conditions
Breast Cancer
Interventions
Drug: INCB007839 300mg BID
First Posted Date
2010-12-06
Last Posted Date
2012-01-25
Lead Sponsor
Incyte Corporation
Target Recruit Count
20
Registration Number
NCT01254136

Study of Efficacy and Safety in Polycythemia Vera Subjects Who Are Resistant to or Intolerant of Hydroxyurea: JAK Inhibitor INC424 (INCB018424) Tablets Versus Best Available Care: (The RESPONSE Trial)

Phase 3
Completed
Conditions
Polycythemia Vera
Interventions
Other: Best Available Therapy (BAT)
First Posted Date
2010-11-19
Last Posted Date
2019-03-06
Lead Sponsor
Incyte Corporation
Target Recruit Count
222
Registration Number
NCT01243944

A Dose-escalation Study in Subjects With Advanced Malignancies

Phase 1
Completed
Conditions
Solid Tumors and Hematologic Malignancy
Interventions
First Posted Date
2010-09-06
Last Posted Date
2018-01-17
Lead Sponsor
Incyte Corporation
Target Recruit Count
52
Registration Number
NCT01195311

A Dose-escalation Study in Subjects With Advanced Malignancies

Phase 1
Completed
Conditions
Advanced Cancer
Metastatic Cancer
Solid Tumor
Interventions
First Posted Date
2010-02-22
Last Posted Date
2017-11-22
Lead Sponsor
Incyte Corporation
Target Recruit Count
45
Registration Number
NCT01072266

COntrolled MyeloFibrosis Study With ORal JAK Inhibitor Treatment: The COMFORT-I Trial

Phase 3
Completed
Conditions
MPN (Myeloproliferative Neoplasms)
Interventions
Drug: Placebo
First Posted Date
2009-08-06
Last Posted Date
2018-03-12
Lead Sponsor
Incyte Corporation
Target Recruit Count
309
Registration Number
NCT00952289

INCB028050 Compared to Background Therapy in Patients With Active Rheumatoid Arthritis (RA) With Inadequate Response to Disease Modifying Anti-Rheumatic Drugs

Phase 2
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: Placebo
First Posted Date
2009-05-15
Last Posted Date
2018-09-04
Lead Sponsor
Incyte Corporation
Target Recruit Count
127
Registration Number
NCT00902486

Open Label Trial of INCB07839 to Determine Effect and Safety of INCB007839 Plus Trastuzumab in HER2 Positive Metastatic Breast Cancer

Phase 1
Terminated
Conditions
Breast Cancer
Interventions
First Posted Date
2009-03-18
Last Posted Date
2018-01-18
Lead Sponsor
Incyte Corporation
Target Recruit Count
68
Registration Number
NCT00864175

A Study of Ruxolitinib Phosphate Cream When Applied to Patients With Plaque Psoriasis

First Posted Date
2009-01-12
Last Posted Date
2022-02-08
Lead Sponsor
Incyte Corporation
Target Recruit Count
29
Registration Number
NCT00820950

Open-Label Study to Assess the Safety/Tolerability in Patients With Solid Tumors

Phase 1
Completed
Conditions
Solid Tumors and Hematologic Malignancy
Interventions
First Posted Date
2009-01-12
Last Posted Date
2018-01-17
Lead Sponsor
Incyte Corporation
Target Recruit Count
41
Registration Number
NCT00820560
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