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๐Ÿ‡บ๐Ÿ‡ธUnited States
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PANGEA-IMBBP: Personalized Antibodies for Gastro-Esophageal Adenocarcinoma - A 1st Pilot Metastatic Trial of Biologics Beyond Progression

Phase 2
Completed
Conditions
Adenocarcinoma
Interventions
First Posted Date
2014-08-11
Last Posted Date
2021-04-08
Lead Sponsor
University of Chicago
Target Recruit Count
80
Registration Number
NCT02213289
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago, Chicago, Illinois, United States

The Effects of Hydromorphone on Responses to Verbal Tasks

Not Applicable
Completed
Conditions
Healthy
Interventions
Drug: 2 mg hydromorphone
Drug: 4 mg hydromorphone
Drug: 1000 mg Acetaminophen
Drug: dextrose
First Posted Date
2014-08-01
Last Posted Date
2018-10-09
Lead Sponsor
University of Chicago
Target Recruit Count
50
Registration Number
NCT02205983
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago Hospital, Chicago, Illinois, United States

Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy

Not Applicable
Completed
Conditions
Thyroid Neoplasms
Goiter, Nodular
Thyroid Nodule
Graves' Disease
Hyperparathyroidism
Interventions
Procedure: Superficial Cervical Plexus Block
Procedure: Local Wound Infiltration
Drug: Marcaine
Drug: 0.9% saline
First Posted Date
2014-07-31
Last Posted Date
2018-03-09
Lead Sponsor
University of Chicago
Target Recruit Count
36
Registration Number
NCT02205801
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago Medical Center, Chicago, Illinois, United States

Selinexor, Carfilzomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Phase 1
Recruiting
Conditions
Refractory Multiple Myeloma
Interventions
First Posted Date
2014-07-24
Last Posted Date
2024-11-22
Lead Sponsor
University of Chicago
Target Recruit Count
100
Registration Number
NCT02199665
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Mount Sinai Medical Center, New York, New York, United States

๐Ÿ‡บ๐Ÿ‡ธ

Mayo Clinic (AZ), Scottsdale, Arizona, United States

๐Ÿ‡บ๐Ÿ‡ธ

Wayne State University Karmanos Cancer Institute, Detroit, Michigan, United States

and more 2 locations

Personalized Decision Support for Older Patients With Diabetes

Not Applicable
Completed
Conditions
Diabetes
Interventions
Other: Personalized Diabetes Care Website
First Posted Date
2014-06-23
Last Posted Date
2016-02-19
Lead Sponsor
University of Chicago
Target Recruit Count
100
Registration Number
NCT02169999
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago Hospitals, Chicago, Illinois, United States

The Effect of NSAIDs After a Rotator Cuff Repair Surgery.

Phase 4
Withdrawn
Conditions
Rotator Cuff Tear
Interventions
Procedure: Rotator cuff repair
Drug: Ibuprofen, Hydrocodone/Acetaminophen, Omeprazole
Drug: Hydrocodone/Acetaminophen
First Posted Date
2014-06-02
Last Posted Date
2023-02-23
Lead Sponsor
University of Chicago
Registration Number
NCT02153177
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago, Chicago, Illinois, United States

A Pharmacodynamic Study of Sirolimus and Metformin in Patients With Advanced Solid Tumors

Phase 1
Completed
Conditions
Breast Neoplasms
Lung Neoplasms
Cancer of Liver
Lymphoma
Cancer of Kidney
Interventions
Drug: Metformin XR
Drug: Delayed Metformin
Drug: Sirolimus
First Posted Date
2014-05-23
Last Posted Date
2019-04-22
Lead Sponsor
University of Chicago
Target Recruit Count
24
Registration Number
NCT02145559
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago, Chicago, Illinois, United States

Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Phase 2
Active, not recruiting
Conditions
Brenner Tumor
Malignant Pleural Effusion
Ovarian Endometrioid Adenocarcinoma
Recurrent Fallopian Tube Cancer
Recurrent Primary Peritoneal Cavity Cancer
Ovarian Clear Cell Cystadenocarcinoma
Stage IIIC Fallopian Tube Cancer
Malignant Ascites
Ovarian Mixed Epithelial Carcinoma
Recurrent Ovarian Epithelial Cancer
Interventions
Drug: metformin hydrochloride
Drug: placebo
Drug: Chemotherapy
First Posted Date
2014-04-24
Last Posted Date
2024-07-31
Lead Sponsor
University of Chicago
Target Recruit Count
110
Registration Number
NCT02122185
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Mitchell Cancer Institute - University of South Alabama, Mobile, Alabama, United States

๐Ÿ‡บ๐Ÿ‡ธ

Rush University Medical Center, Chicago, Illinois, United States

๐Ÿ‡บ๐Ÿ‡ธ

City of Hope, Duarte, California, United States

and more 7 locations

Afatinib in Advanced Refractory Urothelial Cancer

Phase 2
Terminated
Conditions
Distal Urethral Cancer
Recurrent Bladder Cancer
Proximal Urethral Cancer
Recurrent Urethral Cancer
Stage III Bladder Cancer
Stage III Urethral Cancer
Stage IV Bladder Cancer
Stage IV Urethral Cancer
Ureter Cancer
Interventions
Drug: afatinib dimaleate
Other: laboratory biomarker analysis
First Posted Date
2014-04-24
Last Posted Date
2024-05-29
Lead Sponsor
University of Chicago
Target Recruit Count
95
Registration Number
NCT02122172
Locations
๐Ÿ‡บ๐Ÿ‡ธ

NorthShore University Health System, Evanston, Illinois, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago, Chicago, Illinois, United States

๐Ÿ‡บ๐Ÿ‡ธ

Emory University Winship Cancer Institute, Atlanta, Georgia, United States

and more 3 locations

Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty

Not Applicable
Completed
Conditions
Arthroplasty, Replacement, Knee
Nerve Block
Interventions
Device: Adductor Canal Nerve Block Sham Catheter
Device: Adductor Canal Nerve Block Catheter
Drug: Bupivacaine
First Posted Date
2014-04-23
Last Posted Date
2020-10-20
Lead Sponsor
University of Chicago
Target Recruit Count
165
Registration Number
NCT02121392
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago Medicine, Chicago, Illinois, United States

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