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Regeneron Pharmaceuticals

Regeneron Pharmaceuticals logo
🇺🇸United States
Ownership
Public
Established
1988-01-01
Employees
13.4K
Market Cap
$132.4B
Website
http://www.regeneron.com
Introduction

Regeneron Pharmaceuticals, Inc. is a biotechnology company, which engages in the discovery, invention, development, manufacture, and commercialization of medicines. Its product portfolio includes the following brands: Dupixent, Evkeeza, Eylea, Inmazeb, and Kevzara. The firm accelerates the traditional drug development process through its proprietary VelociSuite technologies such as VelocImmune, which uses unique genetically humanized mice to produce optimized fully human antibodies and bispecific antibodies. The company was founded by Alferd G. Gilman, Leonard S. Schleifer, George Damis Yancopoulos, and Eric M. Shooter on January 8, 1988, and is headquartered in Tarrytown, NY.

Study of the Blood Concentrations of Two Formulations of REGN1033 in Healthy Subjects

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2016-04-18
Last Posted Date
2016-10-14
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
28
Registration Number
NCT02741739

Study of the Efficacy and Safety of Intravitreal (IVT) Aflibercept for the Improvement of Moderately Severe to Severe Nonproliferative Diabetic Retinopathy (NPDR)

Phase 3
Completed
Conditions
Nonproliferative Diabetic Retinopathy
Interventions
Drug: Sham
Drug: Intravitreal aflibercept injection [IAI]
First Posted Date
2016-03-24
Last Posted Date
2020-07-30
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
402
Registration Number
NCT02718326
Locations
🇺🇸

Regeneron study Site, Tucker, Georgia, United States

🇬🇧

Regeneron Study Site, London, United Kingdom

🇺🇸

Regeneron Study Ssites, Marietta, Georgia, United States

and more 3 locations

Anti-angiOpoeitin 2 Plus Anti-vascular eNdothelial Growth Factor as a therapY for Neovascular Age Related Macular Degeneration: Evaluation of a fiXed Combination Intravitreal Injection

Phase 2
Completed
Conditions
Neovascular Age-Related Macular Degeneration
Interventions
Drug: Intravitreal Aflibercept Injection (IAI)
First Posted Date
2016-03-18
Last Posted Date
2019-05-07
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
365
Registration Number
NCT02713204
Locations
🇺🇸

Regeneron Investigational Site 3, Phoenix, Arizona, United States

🇺🇸

Regeneron Investigational Site 1, Fort Worth, Texas, United States

🇺🇸

Regeneron Investigational Site 2, Fort Worth, Texas, United States

and more 1 locations

Anti-vasculaR Endothelial Growth Factor plUs Anti-angiopoietin 2 in Fixed comBination therapY: Evaluation for the Treatment of Diabetic Macular Edema

Phase 2
Completed
Conditions
Diabetic Macular Edema
Interventions
Drug: Intravitreal Aflibercept Injection (IAI)
First Posted Date
2016-03-17
Last Posted Date
2018-10-03
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
302
Registration Number
NCT02712008

Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip

Phase 3
Completed
Conditions
Osteoarthritis of the Knee or Hip
Interventions
Drug: Placebo
First Posted Date
2016-02-17
Last Posted Date
2023-10-13
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
5331
Registration Number
NCT02683239
Locations
🇺🇸

Regeneron Investigational Site (4 locations), Phoenix, Arizona, United States

🇬🇧

Regeneron Investigational Site, Sidcup, United Kingdom

🇺🇦

Regeneron Investigational Site #1, Kyiv, Ukraine

and more 5 locations

Clinical Study of CMP-001 in Combination With Pembrolizumab or as a Monotherapy

Phase 1
Completed
Conditions
Melanoma
Interventions
First Posted Date
2016-02-11
Last Posted Date
2023-01-11
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
199
Registration Number
NCT02680184
Locations
🇺🇸

Georgetown, Washington, District of Columbia, United States

🇺🇸

University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States

🇺🇸

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

and more 10 locations

A Study to Learn How Safe and Tolerable Odronextamab and Cemiplimab Are in Adult Patients With B-cell Malignancies

Phase 1
Recruiting
Conditions
Relapsed/Refractory Aggressive B-Cell Lymphoma
Interventions
First Posted Date
2016-01-11
Last Posted Date
2025-04-16
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
62
Registration Number
NCT02651662
Locations
🇵🇱

Copernicus Memorial Hospital, Lodz, Poland

🇺🇸

Harvard Medical School - Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

🇺🇸

University of California Los Angeles Medical Center, Santa Monica, California, United States

and more 36 locations

Open Label, Drug-Drug Interaction (DDI) Study of Dupilumab (REGN668/SAR231893) in Patients With Moderate to Severe Atopic Dermatitis (AD)

First Posted Date
2016-01-06
Last Posted Date
2016-08-22
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
14
Registration Number
NCT02647086
Locations
🇺🇸

Regeneron Study Site, Raleigh, North Carolina, United States

A Study to Determine the Efficacy and Safety of Fasinumab for the Treatment of Adults With Chronic Low Back Pain

Phase 2
Completed
Conditions
Low Back Pain
Interventions
Drug: placebo
First Posted Date
2015-12-02
Last Posted Date
2020-06-16
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
563
Registration Number
NCT02620020

Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to <18 Years of Age With Atopic Dermatitis (AD)

Phase 3
Active, not recruiting
Conditions
Atopic Dermatitis
Interventions
First Posted Date
2015-11-23
Last Posted Date
2024-06-10
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
880
Registration Number
NCT02612454
Locations
🇬🇧

Regeneron Investigational Site, Sheffield, South Yorkshire, United Kingdom

🇩🇪

Regeneron Study Site, Muenchen, Germany

🇺🇸

Regeneron Investigational site, Philadelphia, Pennsylvania, United States

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