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Regeneron Pharmaceuticals

Regeneron Pharmaceuticals logo
🇺🇸United States
Ownership
Public
Established
1988-01-01
Employees
13.4K
Market Cap
$132.4B
Website
http://www.regeneron.com
Introduction

Regeneron Pharmaceuticals, Inc. is a biotechnology company, which engages in the discovery, invention, development, manufacture, and commercialization of medicines. Its product portfolio includes the following brands: Dupixent, Evkeeza, Eylea, Inmazeb, and Kevzara. The firm accelerates the traditional drug development process through its proprietary VelociSuite technologies such as VelocImmune, which uses unique genetically humanized mice to produce optimized fully human antibodies and bispecific antibodies. The company was founded by Alferd G. Gilman, Leonard S. Schleifer, George Damis Yancopoulos, and Eric M. Shooter on January 8, 1988, and is headquartered in Tarrytown, NY.

A Trial to Learn if Different Doses of REGN7544 Are Safe in Healthy Adult Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: Matching Placebo
First Posted Date
2023-08-01
Last Posted Date
2024-08-12
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
80
Registration Number
NCT05970718
Locations
🇳🇿

New Zealand Clinical Research, Christchurch, New Zealand

A Proof-of-Concept Trial to Study the Safety and Activity of Linvoseltamab in Participants With Smoldering Multiple Myeloma at High Risk of Developing Multiple Myeloma

Phase 2
Recruiting
Conditions
Smoldering Multiple Myeloma (SMM)
Interventions
First Posted Date
2023-07-21
Last Posted Date
2024-12-19
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
40
Registration Number
NCT05955508
Locations
🇪🇸

Hospital Universitario Ramon y Cajal, Madrid, Spain

🇪🇸

Clinica Universidad de Navarra - Madrid, Madrid, Spain

🇪🇸

University Hospital Doctor Peset, Valencia, Spain

and more 14 locations

A Trial to Learn if Different Doses of REGN17092 Are Safe in Healthy Adults

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: Matching Placebo
First Posted Date
2023-06-28
Last Posted Date
2025-03-27
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
40
Registration Number
NCT05923424
Locations
🇧🇪

UZ Leuven Gasthuisberg Campus, Leuven, Belgium

Compassionate Use of Dupilumab for Adult Patients With Bullous Pemphigoid

Conditions
Bullous Pemphigoid
First Posted Date
2023-06-18
Last Posted Date
2025-01-07
Lead Sponsor
Regeneron Pharmaceuticals
Registration Number
NCT05906706

A Study to Learn How Well Dupilumab Works in Adult and Adolescent Participants With Eosinophilic Gastritis With or Without Eosinophilic Duodenitis and the Side Effects it May Have

Phase 2
Recruiting
Conditions
Eosinophilic Gastritis (EoG)
Eosinophilic Duodenitis (EoD)
Eosinophilic Gastrointestinal Disease (EGID)
Eosinophilic Gastroenteritis
Interventions
First Posted Date
2023-04-26
Last Posted Date
2025-05-06
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
22
Registration Number
NCT05831176
Locations
🇺🇸

Om Research LLC, Lancaster, California, United States

🇺🇸

Scripps Memorial Hospital La Jolla, La Jolla, California, United States

🇺🇸

University of California - Los Angeles (UCLA), Los Angeles, California, United States

and more 75 locations

A Window of Opportunity Trial to Learn if Linvoseltamab is Safe and Well Tolerated, and How Well it Works in Adult Participants With Recently Diagnosed Multiple Myeloma Who Have Not Already Received Treatment

Phase 1
Recruiting
Conditions
Multiple Myeloma
Interventions
First Posted Date
2023-04-25
Last Posted Date
2025-04-25
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
132
Registration Number
NCT05828511
Locations
🇫🇷

Centre Hospitalier Universitaire (CHU) Montpellier, Montpellier, France

🇫🇷

Hopital Saint Louis, Paris, France

🇫🇷

Hopital Pitié Salpetriere APHP, Paris, France

and more 27 locations

A Trial to Learn How the Combination of Fianlimab With Cemiplimab and Chemotherapy Works Compared With Cemiplimab and Chemotherapy for Treating Adult Patients With Advanced Non-small Cell Lung Cancer

Phase 2
Recruiting
Conditions
Non-small Cell Lung Cancer
Interventions
First Posted Date
2023-04-05
Last Posted Date
2025-05-13
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
950
Registration Number
NCT05800015
Locations
🇺🇸

Crosson Cancer Institute, Fullerton, California, United States

🇺🇸

Arizona Clinical Research Center, Tucson, Arizona, United States

🇺🇸

Yuma Regional Medical Center, Yuma, Arizona, United States

and more 74 locations

A Study of the Incidence of Intraocular Inflammation and Suspected Endophthalmitis Among Patients Treated With Aflibercept, Vial and Pre-filled Syringe, 2014-2022

Completed
Conditions
Suspected Endophthalmitis
Intraocular Inflammation
Interventions
Other: Non Applicable
First Posted Date
2023-03-30
Last Posted Date
2023-12-01
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
155413
Registration Number
NCT05791695
Locations
🇺🇸

Regeneron Research Site, Tarrytown, New York, United States

A Study of DB-OTO, an Adeno-associated Virus (AAV) Based Gene Therapy, in Children/Infants With Hearing Loss Due to Otoferlin Mutations

Phase 1
Recruiting
Conditions
Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)
Interventions
Genetic: DB-OTO
First Posted Date
2023-03-29
Last Posted Date
2025-03-17
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
22
Registration Number
NCT05788536
Locations
🇺🇸

University of California Los Angeles Medical Center, Los Angeles, California, United States

🇺🇸

Nemours Children s Clinic, Jacksonville, Florida, United States

🇺🇸

Nemours Childrens Hospital, Orlando, Florida, United States

and more 9 locations

A Study to Learn if a Combination of Fianlimab and Cemiplimab Versus Cemiplimab Alone is More Effective for Adult Participants With Advanced Non-Small Cell Lung Cancer (NSCLC)

Phase 2
Recruiting
Conditions
Advanced Non-Small Cell Lung Cancer
Interventions
First Posted Date
2023-03-27
Last Posted Date
2025-05-15
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
850
Registration Number
NCT05785767
Locations
🇺🇸

Arizona Clinical Research Center, Tucson, Arizona, United States

🇺🇸

Yuma Regional Medical Center, Yuma, Arizona, United States

🇺🇸

Desert Hematology Oncology Medical Group Incorporated, Rancho Mirage, California, United States

and more 107 locations
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