Laekna Limited

🇭🇰Hong Kong, China
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Evaluate LAE102 in Healthy Subjects and Subjects With Overweight Obesity

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2024-07-09
Last Posted Date
2024-10-14
Lead Sponsor
Laekna Limited
Target Recruit Count
72
Registration Number
NCT06493084
Locations
🇨🇳

Fudan Zhongshan Hospital, Shanghai, Shanghai, China

Human Mass Balance and Biotransformation Study of [14C]Afuresertib

Phase 1
Completed
Conditions
Interventions
First Posted Date
2022-08-05
Last Posted Date
2023-05-15
Lead Sponsor
Laekna Limited
Target Recruit Count
6
Registration Number
NCT05489744
Locations
🇨🇳

The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China

PhI to Solid Tumors and PhII to Locally Advanced or mTNBC

First Posted Date
2022-05-25
Last Posted Date
2024-10-10
Lead Sponsor
Laekna Limited
Target Recruit Count
21
Registration Number
NCT05390710
Locations
🇨🇳

Cancer Hospital Chinese Academy of Medical Sciences, Beijing, Beijing, China

🇨🇳

Sun Yat-sen Memorial Hospital, Guangzhou, China

🇨🇳

Sir RunRun Shaw Hospital Zhejiang University School of Medicine, Hangzhou, China

and more 2 locations

Afuresertib +Sintilimab+Chemotherapy in Patients With Selected Solid Tumors That Resistance to Prior Anti-PD-1/PD-L1

First Posted Date
2022-05-20
Last Posted Date
2024-10-14
Lead Sponsor
Laekna Limited
Target Recruit Count
167
Registration Number
NCT05383482
Locations
🇨🇳

Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China

🇨🇳

Beijing Cancer Hospital, Beijing, Beijing, China

🇨🇳

Chongqing Cancer Hospital, Chongqing, Chengdu, China

and more 2 locations

Study Evaluating Efficacy & Safety of Afuresertib Plus Fulvestrant in Patients w/ Locally Advanced or Metastatic HR+/HER2- Breast Cancer

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2021-04-20
Last Posted Date
2024-10-10
Lead Sponsor
Laekna Limited
Target Recruit Count
256
Registration Number
NCT04851613
Locations
🇺🇸

Providence St. Johns Health Center, Santa Monica, California, United States

🇺🇸

Virginia Cancer Specialists, Fairfax, Virginia, United States

🇺🇸

Piedmont Cancer Institute, Atlanta, Georgia, United States

and more 4 locations

Study With Afuresertib and Paclitaxel in Platinum Resistant Ovarian

First Posted Date
2020-05-05
Last Posted Date
2024-08-19
Lead Sponsor
Laekna Limited
Target Recruit Count
150
Registration Number
NCT04374630
Locations
🇺🇸

University of Massachusetts, Worcester, Massachusetts, United States

🇺🇸

University of Texas Health Science Center at Houston, Houston, Texas, United States

🇺🇸

US Texas Oncology, San Antonio, Texas, United States

and more 42 locations

Dose-Escalation and Efficacy Study of LAE001/Prednisone Plus Afuresertib Patients With m-CRPC

First Posted Date
2019-08-19
Last Posted Date
2024-10-10
Lead Sponsor
Laekna Limited
Target Recruit Count
49
Registration Number
NCT04060394
Locations
🇰🇷

National Cancer Center, Goyang-si, Gyeonggido, Korea, Republic of

🇺🇸

University of Chicago, Chicago, Illinois, United States

🇺🇸

Associated Medical Professionals of NY, Syracuse, New York, United States

and more 14 locations

A Study on the Safety and Efficacy of LAE001 in the Treatment of Metastatic Prostate Cancer

Phase 1
Suspended
Conditions
Interventions
First Posted Date
2019-02-18
Last Posted Date
2024-10-10
Lead Sponsor
Laekna Limited
Target Recruit Count
33
Registration Number
NCT03843918
Locations
🇨🇳

Fudan Cancer Hospital, Shanghai, Shanghai, China

🇨🇳

ZheJiang Cancer Hospital, Hangzhou, Zhejiang, China

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