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LOXO ONCOLOGY, INC.

LOXO ONCOLOGY, INC. logo
πŸ‡ΊπŸ‡ΈUnited States
Ownership
Subsidiary
Established
2013-01-01
Employees
1K
Market Cap
-
Website
http://www.loxooncology.com

Clinical Trials

23

Active:12
Completed:7

Trial Phases

3 Phases

Phase 1:8
Phase 2:2
Phase 3:6

Drug Approvals

1

FDA:1

Drug Approvals

VITRAKVI

Approval Date
Dec 5, 2018
FDA

Clinical Trials

Distribution across different clinical trial phases (16 trials with phase data)β€’ Click on a phase to view related trials

Phase 1
8 (50.0%)
Phase 3
6 (37.5%)
Phase 2
2 (12.5%)

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Phase 2
Recruiting
Conditions
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Interventions
First Posted Date
2024-09-19
Last Posted Date
2025-09-08
Lead Sponsor
Loxo Oncology, Inc.
Target Recruit Count
249
Registration Number
NCT06588478
Locations
πŸ‡ΊπŸ‡Έ

Ironwood Cancer & Research Centers, Chandler, Arizona, United States

πŸ‡ΊπŸ‡Έ

City of Hope National Medical Center, Irvine, California, United States

πŸ‡ΊπŸ‡Έ

Palo Alto Medical Foundation Research Institute (PAMFRI), Palo Alto, California, United States

and more 132 locations

A Study of Pirtobrutinib (LY3527727 [LOXO-305]) Versus Placebo in Participants With Relapsing Multiple Sclerosis

Phase 2
Withdrawn
Conditions
Relapsing Multiple Sclerosis
Multiple Sclerosis
Interventions
Drug: Placebo
First Posted Date
2023-10-27
Last Posted Date
2024-03-27
Lead Sponsor
Loxo Oncology, Inc.
Registration Number
NCT06104683
Locations
πŸ‡ΊπŸ‡Έ

University of South Florida, Tampa, Florida, United States

πŸ‡ΊπŸ‡Έ

Clinical Trial Network, Houston, Texas, United States

πŸ‡ΊπŸ‡Έ

Swedish Medical Center-501 E Hampden Ave, Seattle, Washington, United States

and more 1 locations

A Study of the Effect of Food on Selpercatinib (LY3527723) in Healthy Participants

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2022-04-12
Last Posted Date
2025-03-21
Lead Sponsor
Loxo Oncology, Inc.
Target Recruit Count
46
Registration Number
NCT05324124
Locations
πŸ‡ΈπŸ‡¬

Lilly Centre for Clinical Pharmacology, Singapore, Singapore

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Phase 3
Recruiting
Conditions
Chronic Lymphocytic Leukemia
Leukemia, B-cell
Leukemia, Lymphocytic
Small Lymphocytic Lymphoma
Interventions
First Posted Date
2022-02-24
Last Posted Date
2025-09-09
Lead Sponsor
Loxo Oncology, Inc.
Target Recruit Count
662
Registration Number
NCT05254743
Locations
πŸ‡ΊπŸ‡Έ

Pacific Cancer Medical Center, Inc, Anaheim, California, United States

πŸ‡ΊπŸ‡Έ

TOI Clinical Research, Cerritos, California, United States

πŸ‡ΊπŸ‡Έ

Stanford School of Medicine-Cancer Clinical Trials Office, Palo Alto, California, United States

and more 145 locations

A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LY3527727) and Rosuvastatin in Healthy Participants

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2022-01-04
Last Posted Date
2022-04-15
Lead Sponsor
Loxo Oncology, Inc.
Target Recruit Count
34
Registration Number
NCT05176314
Locations
πŸ‡ΊπŸ‡Έ

QPS Bio-Kinetic Clinical Applications, Springfield, Missouri, United States

πŸ‡ΊπŸ‡Έ

Covance Dallas, Dallas, Texas, United States

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