Impact on Anxiety and Motivation of COVID-19 and Predictors of Individual Responses
- Conditions
- AnxietyHealthy Volunteers
- Interventions
- Behavioral: Computer task questionnaires
- First Posted Date
- 2020-05-06
- Last Posted Date
- 2025-05-31
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 2962
- Registration Number
- NCT04377100
- Locations
- πΊπΈ
National Institute of Mental Health (NIMH), Bethesda, Maryland, United States
Mental Health Impact of COVID-19 Pandemic on NIMH Research Participants and Volunteers
- Conditions
- Anxiety DisorderHealthy VolunteerPreexisting Medical ConditionMood Disorder
- First Posted Date
- 2020-04-09
- Last Posted Date
- 2023-04-28
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 3655
- Registration Number
- NCT04339790
- Locations
- πΊπΈ
National Institute of Mental Health (NIMH), Bethesda, Maryland, United States
Ask Suicide-Screening Questions (ASQ) for Youth With Autism Spectrum and Neurodevelopmental Disorders
- Conditions
- Suicidal Ideation
- First Posted Date
- 2020-03-23
- Last Posted Date
- 2025-07-02
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 278
- Registration Number
- NCT04317118
- Locations
- πΊπΈ
Kennedy Krieger Institute/Johns Hopkins University, Baltimore, Maryland, United States
πΊπΈNational Institutes of Health Clinical Center, Bethesda, Maryland, United States
πΊπΈNationwide Children's Hospital/ Ohio State University, Columbus, Ohio, United States
Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression
- Conditions
- Major DepressionDepressionMajor Depressive Disorder
- Interventions
- Device: Arm 1, 2, 3 device interventionsDrug: Arm 1, 2, 3 drug InterventionsOther: Arm 2 InterventionsDrug: Arm 1 and 2 Interventions
- First Posted Date
- 2019-06-04
- Last Posted Date
- 2025-06-22
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 70
- Registration Number
- NCT03973268
- Locations
- πΊπΈ
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) Radioligand
- Conditions
- Dementia
- Interventions
- First Posted Date
- 2019-05-22
- Last Posted Date
- 2024-05-01
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 13
- Registration Number
- NCT03958630
- Locations
- πΊπΈ
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Novel PET Radioligand as an Inflammatory Biomarker in Musculoskeletal Conditions
- Conditions
- Rheumatoid ArthritisMyositisInflammatoryHealthy Volunteers
- Interventions
- Diagnostic Test: 11C-MC1
- First Posted Date
- 2019-04-11
- Last Posted Date
- 2025-03-30
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 30
- Registration Number
- NCT03912428
- Locations
- πΊπΈ
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Title: Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST)
- Conditions
- Unipolar Depression
- Interventions
- Device: MagPro TMS stimulator and coilDevice: MRIDevice: MECTA paired with the 4X1 HD-ECT
- First Posted Date
- 2019-03-29
- Last Posted Date
- 2025-02-27
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 20
- Registration Number
- NCT03895658
- Locations
- πΊπΈ
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Title: Evaluation of a Novel PET Radioligand for Phosphodiesterase-4D (PDE4D)
- First Posted Date
- 2019-03-04
- Last Posted Date
- 2021-03-22
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 3
- Registration Number
- NCT03861000
- Locations
- πΊπΈ
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Effects of an ER Beta Agonist (Lilly Compound LY500307) on Estradiol-Withdrawal-Induced Mood Symptoms in Women With Past Perimenopausal Depression
- Conditions
- Perimenopause-Related Depression
- Interventions
- Drug: ER beta agonistOther: Placebo
- First Posted Date
- 2018-09-28
- Last Posted Date
- 2024-10-18
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 68
- Registration Number
- NCT03689543
- Locations
- πΊπΈ
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Evaluation of a Novel PET Radioligand to Image OGA
- First Posted Date
- 2018-08-15
- Last Posted Date
- 2019-06-28
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 28
- Registration Number
- NCT03632226
- Locations
- πΊπΈ
National Institutes of Health Clinical Center, Bethesda, Maryland, United States