MedPath

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

🇺🇸United States
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Employees
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Market Cap
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Website

Vedolizumab (Anti-alpha4beta7) in Subjects With HIV Infection Undergoing Analytical Treatment Interruption

Phase 1
Completed
Conditions
HIV
Interventions
Biological: Entyvio (Vedolizumab)
First Posted Date
2016-06-02
Last Posted Date
2020-02-24
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
26
Registration Number
NCT02788175
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Safety, Tolerability, and Pharmacokinetics of SAB-301 in Healthy Adults

Phase 1
Completed
Conditions
Middle East Respiratory Syndrome Coronavirus
Interventions
Other: Normal (9%) Saline
Biological: SAB-301
First Posted Date
2016-06-02
Last Posted Date
2018-06-12
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
38
Registration Number
NCT02788188
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

PfSPZ Challenge in Non-immune Adults in Baltimore, USA

Phase 1
Completed
Conditions
Plasmodium Falciparum Infection
Interventions
Biological: PfSPZ (7G8) Challenge
Biological: PfSPZ (NF54) Challenge
First Posted Date
2016-05-23
Last Posted Date
2019-01-28
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
30
Registration Number
NCT02780154
Locations
🇺🇸

University of Maryland School of Medicine - Center for Vaccine Development - Baltimore, Baltimore, Maryland, United States

Phase I, Dose Escalation Study to Evaluate the Safety and Pharmacokinetics of NTM-1632

Phase 1
Completed
Conditions
Botulism
Interventions
Biological: NTM-1632
Other: Placebo
First Posted Date
2016-05-20
Last Posted Date
2018-10-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
24
Registration Number
NCT02779140
Locations
🇺🇸

Duke Human Vaccine Institute - Duke Clinical Vaccine Unit, Durham, North Carolina, United States

Evaluating the Safety and Pharmacokinetics of Maraviroc in HIV-1-Exposed Infants at Risk of Acquiring HIV-1 Infection

Phase 1
Completed
Conditions
HIV Infections
Interventions
First Posted Date
2016-05-19
Last Posted Date
2022-01-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
47
Registration Number
NCT02778204
Locations
🇺🇸

Usc La Nichd Crs, Los Angeles, California, United States

🇺🇸

St. Jude Children's Research Hospital CRS, Memphis, Tennessee, United States

🇰🇪

Kenya Medical Research Institute / Walter Reed Project Clinical Research Center, Kericho CRS, Kericho, Kenya

and more 6 locations

PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States

Phase 1
Completed
Conditions
Plasmodium Falciparum Infection
Interventions
Drug: Chloroquine
Biological: PfSPZ (NF54) Challenge
Other: Placebo
First Posted Date
2016-05-16
Last Posted Date
2019-12-27
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
28
Registration Number
NCT02773979
Locations
🇺🇸

Kaiser Permanente Washington Health Research Institute - Vaccines and Infectious Diseases, Seattle, Washington, United States

LACTIN-V Study for Recurrent Bacterial Vaginosis

Phase 2
Completed
Conditions
Bacterial Vaginosis
Interventions
Biological: Lactobacillus crispatus CTV-05
Other: Placebo
Drug: Metronidazole
First Posted Date
2016-05-09
Last Posted Date
2020-03-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
228
Registration Number
NCT02766023
Locations
🇺🇸

University of California, San Diego - Antiviral Research Center, San Diego, California, United States

🇺🇸

Washington University School of Medicine in St. Louis - Infectious Disease Clinical Research Unit, Saint Louis, Missouri, United States

🇺🇸

Cook County Health and Hospitals System - Ruth M Rothstein CORE Center, Chicago, Illinois, United States

and more 1 locations

Impact of Allo- and Autoantibodies on Chronic Cardiac Allograft Function

Completed
Conditions
Pediatric Heart Transplantation
Pediatric Heart Transplant Recipients
First Posted Date
2016-04-27
Last Posted Date
2019-11-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
407
Registration Number
NCT02752789
Locations
🇺🇸

Emory University School of Medicine, Atlanta, Georgia, United States

🇺🇸

Columbia University Medical Center, New York, New York, United States

🇺🇸

Children's Hospital Boston, Boston, Massachusetts, United States

and more 6 locations

A Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of MVA-BN Yellow Fever Vaccine With and Without Montanide ISA-720 Adjuvant in 18-45 Year Old Healthy Volunteers

Phase 1
Completed
Conditions
Yellow Fever
Yellow Fever Immunisation
Interventions
Drug: ISA-720
Other: Placebo
Biological: MVA Smallpox Vaccine
Biological: MVA-BN Yellow Fever Vaccine
Biological: YF Vax 17D Strain
First Posted Date
2016-04-19
Last Posted Date
2023-10-02
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
92
Registration Number
NCT02743455
Locations
🇺🇸

University of Iowa - Vaccine Research and Education Unit, Iowa City, Iowa, United States

🇺🇸

Saint Louis University Center for Vaccine Development, Saint Louis, Missouri, United States

A Cohort Study of Operationally Tolerant Allograft Recipients

Terminated
Conditions
Kidney Transplant
Liver Transplant
Interventions
Procedure: Blood Draw
First Posted Date
2016-04-19
Last Posted Date
2021-09-21
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
41
Registration Number
NCT02743793
Locations
🇺🇸

Emory University School of Medicine, Atlanta, Georgia, United States

🇺🇸

Children's Hospital of Pittsburg of UPMC, Pittsburgh, Pennsylvania, United States

🇺🇸

Ann & Robert H. Lurie Children's Memorial Hospital of Chicago, Chicago, Illinois, United States

and more 2 locations
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