Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
- Conditions
- X-linked Severe Combined Immunodeficiency (XSCID)
- Interventions
- Biological: Ex vivo culture and transduction of the patient's autologous CD34+ HSC with lentivirus vector VSV-G pseudotyped CL20- 4i-EF1alpha-hgammac-OPT vector
- First Posted Date
- 2011-03-01
- Last Posted Date
- 2025-06-05
- Target Recruit Count
- 40
- Registration Number
- NCT01306019
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Viral Infections in Healthy and Immunocompromised Hosts
- Conditions
- Anogenital HerpesHerpes LabialisCOVID-19
- First Posted Date
- 2011-03-01
- Last Posted Date
- 2025-06-04
- Target Recruit Count
- 1000
- Registration Number
- NCT01306084
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Safety of and Immune Response to Dolutegravir in HIV-1 Infected Infants, Children, and Adolescents
- Conditions
- HIV Infections
- Interventions
- Drug: DTG film-coated tabletsDrug: DTG granules for suspensionDrug: DTG dispersible tablets
- First Posted Date
- 2011-02-24
- Last Posted Date
- 2024-12-12
- Target Recruit Count
- 181
- Registration Number
- NCT01302847
- Locations
- 🇺🇸
Seattle Children's Research Institute CRS (Site ID: 5017), Seattle, Washington, United States
🇿🇦Wits RHI Shandukani Research Centre CRS (Site ID: 8051), Johannesburg, Gauteng, South Africa
🇺🇸David Geffen School of Medicine at UCLA NICHD CRS (Site ID: 5112), Los Angeles, California, United States
Oral Urea Breath Testing for Diagnosis and Treatment Response in Pulmonary Tuberculosis
- Conditions
- TuberculosisUrea Breath Test
- First Posted Date
- 2011-02-23
- Last Posted Date
- 2018-04-05
- Target Recruit Count
- 113
- Registration Number
- NCT01301144
- Locations
- 🇲🇱
Unviersite de Bamako, Bamako, Mali
Safety Evaluation of an Experimental Treatment, Intradermal Human Fcγ1-Fel d1 Fusion Protein (GFD), for Cat Allergy
- Conditions
- Cat Allergy
- Interventions
- Biological: Intradermal Human Fcγ1-Fel d1 fusion proteinBiological: Positive Control - standardized cat hair allergenic extract (CAT)Biological: Positive Control - Histamine PrickBiological: Negative Control - Intradermal Diluent
- First Posted Date
- 2011-02-09
- Last Posted Date
- 2014-02-20
- Target Recruit Count
- 4
- Registration Number
- NCT01292070
- Locations
- 🇦🇺
Alfred Hospital and Monash University, Melbourne, Victoria, Australia
Proteogenomic Biomarker Panels in a Serial Blood & Urine Monitoring Study of Kidney Transplant Recipients
- Conditions
- Kidney TransplantKidney Transplantation
- First Posted Date
- 2011-02-04
- Last Posted Date
- 2017-08-14
- Target Recruit Count
- 307
- Registration Number
- NCT01289717
- Locations
- 🇺🇸
Mayo Clinic, Division of Nephrology, Phoenix, Arizona, United States
🇺🇸The Cleveland Clinic, Cleveland, Ohio, United States
🇺🇸Medical University of South Carolina, Division of Transplant, Charleston, South Carolina, United States
Praziquantel-Pharmacokinetic Study
- First Posted Date
- 2011-02-03
- Last Posted Date
- 2019-01-18
- Target Recruit Count
- 47
- Registration Number
- NCT01288872
- Locations
- 🇵🇭
Research Institute for Tropical Medicine - Health Compound, Muntinlupa City, National Capital Region, Philippines
Prevention of Cardiac Allograft Vasculopathy Using Rituximab (Rituxan) Therapy in Cardiac Transplantation
- Conditions
- Cardiac Allograft VasculopathyHeart Transplant Recipients
- Interventions
- Biological: Rituximab induction/conventional immunosuppression (tacrolimus, MMF, and steroid taper)
- First Posted Date
- 2011-01-19
- Last Posted Date
- 2020-08-25
- Target Recruit Count
- 362
- Registration Number
- NCT01278745
- Locations
- 🇺🇸
Ronald Regan UCLA Medical Center, Los Angeles, California, United States
🇺🇸Northwestern University, Chicago, Illinois, United States
🇺🇸University of California San Francisco, San Francisco, California, United States
Safety of and Immune Response to an Investigational HIV-1 Vaccine With or Without Interleukin-12 (IL-12) in HIV-1 Infected Adults
- Conditions
- HIV Infections
- Interventions
- Other: PlaceboBiological: Profectus HIV MAG pDNA vaccineBiological: IL-12
- First Posted Date
- 2010-12-24
- Last Posted Date
- 2021-11-01
- Target Recruit Count
- 62
- Registration Number
- NCT01266616
- Locations
- 🇺🇸
UCLA CARE Center CRS, Los Angeles, California, United States
🇺🇸Massachusetts General Hospital Clinical Research Site (MGH CRS) CRS, Boston, Massachusetts, United States
🇺🇸Stanford AIDS Clinical Trials Unit CRS, Palo Alto, California, United States
Safety and Immunogenicity of Sequential Rotavirus Vaccine Schedules
- Conditions
- Rotavirus Infection
- Interventions
- Biological: RotaTeq®Biological: Rotarix®
- First Posted Date
- 2010-12-24
- Last Posted Date
- 2014-10-28
- Target Recruit Count
- 1384
- Registration Number
- NCT01266850
- Locations
- 🇺🇸
Primary Physicians Research Inc. - Pittsburgh, Pittsburgh, Pennsylvania, United States
🇺🇸The University of Texas Medical Branch - Sealy Center for Vaccine Development (SCVD), Galveston, Texas, United States
🇺🇸Baylor College of Medicine - Molecular Virology and Microbiology, Houston, Texas, United States