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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Phase III Study of ICI35,868 (Diprivan) With and Without EES0000645/A (SDS) on Gastrointestinal Endoscopy

Phase 3
Completed
Conditions
Sedation to be Moderate for a Diagnostic Gastrointestinal Endoscopy and Gastrointestinal Endoscopic Polypectomy
Interventions
Drug: ICI35,868 (Diprivan)
Drug: ICI35,868 (Diprivan) + EES0000645/A (SDS)
First Posted Date
2013-10-11
Last Posted Date
2015-11-27
Lead Sponsor
AstraZeneca
Target Recruit Count
279
Registration Number
NCT01961349
Locations
🇯🇵

Research Site, Yokohama-shi, Japan

Dose-escalation Study to Assess Selumetinib Safety, Tolerability and PK

Phase 1
Completed
Conditions
Healthy Volunteers Pharmacokinetic Study
Interventions
First Posted Date
2013-10-10
Last Posted Date
2014-06-02
Lead Sponsor
AstraZeneca
Target Recruit Count
117
Registration Number
NCT01960374
Locations
🇬🇧

Research Site, London, United Kingdom

MEDI7183 Phase 2 Study in Japanese Ulcerative Colitis Patients

Phase 2
Completed
Conditions
Ulcerative Colitis
Interventions
Drug: MEDI7183 high dose
Drug: MEDI7183 low dose
Drug: Matching Placebo
Drug: MEDI7183 medium dose
First Posted Date
2013-10-09
Last Posted Date
2019-07-05
Lead Sponsor
AstraZeneca
Target Recruit Count
44
Registration Number
NCT01959165
Locations
🇯🇵

Research Site, Yokohama-shi, Japan

To Assess Safety, Tolerability and Pharmacodynamics of Intravenous MEDI8111 After Single Ascending Doses.

Phase 1
Completed
Conditions
Healthy Subjects
Interventions
Other: Placebo
First Posted Date
2013-10-09
Last Posted Date
2016-02-04
Lead Sponsor
AstraZeneca
Target Recruit Count
157
Registration Number
NCT01958645
Locations
🇬🇧

Research Site, London, United Kingdom

A Phase 1, Dose-escalation Study of MEDI-551 in Japanese Adult Patients With Relapsed or Refractory Advanced B-cell Malignancies

Phase 1
Completed
Conditions
Advanced B Cell Malignancies
Blood Cancer
Interventions
First Posted Date
2013-10-08
Last Posted Date
2017-06-12
Lead Sponsor
AstraZeneca
Target Recruit Count
32
Registration Number
NCT01957579
Locations
🇯🇵

Research Site, Nagoya-shi, Japan

A Retrospective, Non-interventional, Multicenter, Observational Chart Review Study to Explore the Clinical Benefits of Retreatment With TKI in the Real World.

Completed
Conditions
Locally Advanced or Metastatic EGFR Mutated NSCLC.
First Posted Date
2013-10-07
Last Posted Date
2015-11-04
Lead Sponsor
AstraZeneca
Target Recruit Count
200
Registration Number
NCT01955681
Locations
🇨🇳

Research Site, Taipei, Taiwan

AZD6738 First Time in Patient Multiple Ascending Dose Study

Phase 1
Completed
Conditions
11q-deleted Relapsed/Refractory Chronic Lymphocytic Leukaemia (CLL),
Prolymphocytic Leukaemia (PLL)
B Cell Lymphomas
Interventions
Drug: Administration of AZD6738
First Posted Date
2013-10-07
Last Posted Date
2014-06-19
Lead Sponsor
AstraZeneca
Target Recruit Count
2
Registration Number
NCT01955668
Locations
🇺🇸

Research Site, La Jolla, California, United States

Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome

Completed
Conditions
Acute Coronary Syndrome
First Posted Date
2013-09-30
Last Posted Date
2017-02-24
Lead Sponsor
AstraZeneca
Target Recruit Count
4992
Registration Number
NCT01952392
Locations
🇫🇷

Research Site, Paris, France

To Determine the Relative Bioavailability of Different Formulations of AZD9291 and the Effect of Food.

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2013-09-26
Last Posted Date
2017-03-31
Lead Sponsor
AstraZeneca
Target Recruit Count
35
Registration Number
NCT01951599
Locations
🇺🇸

Research Site, Overland Park, Kansas, United States

Selumetinib (AZD6244, ARRY-142886) J-BTC Phase 1 Study

Phase 1
Terminated
Conditions
Inoperable Locally Advanced or Metastatic Biliary Tract Cancer
Interventions
First Posted Date
2013-09-25
Last Posted Date
2016-05-13
Lead Sponsor
AstraZeneca
Target Recruit Count
6
Registration Number
NCT01949870
Locations
🇯🇵

AZD6244 PhI Japanese Gem/, Chuo Ku, Tokyo, Japan

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