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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

A Study of Acalabrutinib Plus Venetoclax and Rituximab in Participants With Treatment Naïve Mantle Cell Lymphoma

Phase 2
Active, not recruiting
Conditions
Mantle Cell Lymphoma (MCL)
Interventions
First Posted Date
2023-07-19
Last Posted Date
2025-03-04
Lead Sponsor
AstraZeneca
Target Recruit Count
108
Registration Number
NCT05951959
Locations
🇬🇧

Research Site, Plymouth, United Kingdom

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Phase 3
Recruiting
Conditions
Breast Cancer, Early Breast Cancer
Interventions
First Posted Date
2023-07-19
Last Posted Date
2025-05-21
Lead Sponsor
AstraZeneca
Target Recruit Count
5500
Registration Number
NCT05952557
Locations
🇬🇧

Research Site, Whitchurch, United Kingdom

Brazilian Reality of Urinary Bladder Cancers - BRA-BLADDER

Completed
Conditions
Muscle-invasive Bladder Cancer
Non Muscle Invasive Bladder Cancer
Urothelial Carcinoma
First Posted Date
2023-07-14
Last Posted Date
2025-04-11
Lead Sponsor
AstraZeneca
Target Recruit Count
400
Registration Number
NCT05945108
Locations
🇧🇷

Research Site, Sao Paulo, Brazil

BCG in Combination With Durvalumab in Adult BCG-naïve, High-risk NMIBC Participants

Phase 3
Active, not recruiting
Conditions
Non-Muscle- Invasive Bladder Cancer
Interventions
First Posted Date
2023-07-13
Last Posted Date
2025-05-09
Lead Sponsor
AstraZeneca
Target Recruit Count
100
Registration Number
NCT05943106
Locations
🇺🇸

Research Site, Spokane, Washington, United States

A Study to Investigate Efficacy and Safety of Ceralasertib Plus Durvalumab in Participants Aged ≥ 18 Years With Advanced or Metastatic Non-small Cell Lung Cancer Whose Disease Progressed on or After Prior Anti-PD-(L)1 Therapy and Platinum-based Chemotherapy

Phase 2
Active, not recruiting
Conditions
Advanced or Metastatic NSCLC
Interventions
First Posted Date
2023-07-12
Last Posted Date
2025-02-26
Lead Sponsor
AstraZeneca
Target Recruit Count
39
Registration Number
NCT05941897
Locations
🇷🇺

Research Site, St. Petersburg, Russian Federation

A Non-interventional Prospective Study of Early HER2-negative High-risk Breast Cancer and BRCA1/2 Mutations Prevalence in RussiA

Active, not recruiting
Conditions
Breast Cancer
First Posted Date
2023-07-11
Last Posted Date
2025-01-30
Lead Sponsor
AstraZeneca
Target Recruit Count
625
Registration Number
NCT05939128
Locations
🇷🇺

Research Site, Yaroslavl, Russian Federation

A Study to Investigate the Biological Effects of Saruparib (AZD5305), Darolutamide, and in Combination in Men With Newly Diagnosed Prostate Cancer.

Phase 1
Recruiting
Conditions
Prostate Cancer
Interventions
Drug: Saruparib (AZD5305)
Other: No Treatment
First Posted Date
2023-07-10
Last Posted Date
2025-04-27
Lead Sponsor
AstraZeneca
Target Recruit Count
120
Registration Number
NCT05938270
Locations
🇬🇧

Research Site, Newcastle upon Tyne, United Kingdom

Benralizumab Patient Access Programme Study: Retrospective Study in UK Severe Asthma Centres

Completed
Conditions
Asthma
First Posted Date
2023-07-06
Last Posted Date
2023-11-28
Lead Sponsor
AstraZeneca
Target Recruit Count
276
Registration Number
NCT05932849
Locations
🇬🇧

Addenbrookes Hospital, Cambridge, United Kingdom

🇬🇧

St Bartholomew's Hospital, London, United Kingdom

🇬🇧

St James's University Hospital, Leeds, United Kingdom

and more 5 locations

Study of AZD3152 Intramuscular Injection or Intravenous Infusion in Healthy Japanese Adult Participants

Phase 1
Completed
Conditions
COVID-19, SARS-CoV-2
Interventions
Biological: Placebo (Cohort 3)
Biological: Placebo (Cohort 2)
Biological: AZD3152 (Cohort 3)
Biological: AZD3152 (Cohort 2)
Biological: AZD3152 (Cohort 1)
Biological: Placebo (Cohort 1)
First Posted Date
2023-07-06
Last Posted Date
2024-12-27
Lead Sponsor
AstraZeneca
Target Recruit Count
24
Registration Number
NCT05932641
Locations
🇯🇵

Research Site, Fukuoka-shi, Japan

OPTIMISE-CKD Drug Utilization

Completed
Conditions
Chronic Kidney Disease
First Posted Date
2023-07-06
Last Posted Date
2024-04-17
Lead Sponsor
AstraZeneca
Target Recruit Count
2682052
Registration Number
NCT05932901
Locations
🇸🇪

Research Site, Uppsala, Sweden

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