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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Tezepelumab Efficacy and Safety in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma

Phase 3
Terminated
Conditions
Asthma
Interventions
First Posted Date
2022-05-31
Last Posted Date
2025-04-09
Lead Sponsor
AstraZeneca
Target Recruit Count
125
Registration Number
NCT05398263
Locations
🇹🇷

Research Site, Izmir, Turkey

A Study to Assess the Effect of AZD5462 on the Pharmacokinetics of Midazolam, Rosuvastatin and Digoxin

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2022-05-27
Last Posted Date
2023-12-13
Lead Sponsor
AstraZeneca
Target Recruit Count
32
Registration Number
NCT05395117
Locations
🇺🇸

Research Site, Brooklyn, Maryland, United States

PASS of Paediatric Patients Initiating Selumetinib

Recruiting
Conditions
Neurofibromatosis Type 1
First Posted Date
2022-05-24
Last Posted Date
2025-06-03
Lead Sponsor
AstraZeneca
Target Recruit Count
125
Registration Number
NCT05388370
Locations
🇬🇧

Research Site, Newcastle, United Kingdom

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects

Phase 1
Completed
Conditions
Dyslipidemia
Interventions
First Posted Date
2022-05-20
Last Posted Date
2024-07-19
Lead Sponsor
AstraZeneca
Target Recruit Count
183
Registration Number
NCT05384262
Locations
🇬🇧

Research Site, Harrow, United Kingdom

FAsenra Safety Trial in India

Phase 4
Completed
Conditions
In Adult Patients of Severe Asthma With Eosinophilic Phenotype in India
Interventions
First Posted Date
2022-05-20
Last Posted Date
2024-12-11
Lead Sponsor
AstraZeneca
Target Recruit Count
139
Registration Number
NCT05384938
Locations
🇮🇳

Research Site, Vishakhapatnam, India

A Randomized, Open-label, Dose-ranging Study in Adults and Pediatric Individuals ≥ 12 Years of Age to Assess the Safety, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of AZD7442, for Pre-exposure Prophylaxis of COVID-19

Phase 2
Terminated
Conditions
Coronavirus Disease 2019 (COVID-19)
Interventions
First Posted Date
2022-05-17
Last Posted Date
2024-10-23
Lead Sponsor
AstraZeneca
Target Recruit Count
251
Registration Number
NCT05375760
Locations
🇺🇸

Research Site, Annandale, Virginia, United States

A Study of Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02)

First Posted Date
2022-05-16
Last Posted Date
2025-04-13
Lead Sponsor
AstraZeneca
Target Recruit Count
644
Registration Number
NCT05374512
Locations
🇬🇧

Research Site, Warwick, United Kingdom

Savolitinib Combine With Durvalumab in EGFR Wild-type Locally Advanced or Metastatic NSCLC

Phase 2
Active, not recruiting
Conditions
Lung Cancer
Interventions
First Posted Date
2022-05-16
Last Posted Date
2025-04-27
Lead Sponsor
AstraZeneca
Target Recruit Count
47
Registration Number
NCT05374603
Locations
🇨🇳

Research Site, Zhengzhou, China

Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer

Phase 1
Recruiting
Conditions
Metastatic Prostate Cancer
Interventions
First Posted Date
2022-05-10
Last Posted Date
2025-05-09
Lead Sponsor
AstraZeneca
Target Recruit Count
190
Registration Number
NCT05367440
Locations
🇬🇧

Research Site, Plymouth, United Kingdom

A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]AZD9833

Phase 1
Completed
Conditions
ER-positive, HER2-negative Breast Cancer
Interventions
Drug: [14C]AZD9833 Oral Solution, 75 mg
First Posted Date
2022-05-06
Last Posted Date
2024-06-21
Lead Sponsor
AstraZeneca
Target Recruit Count
6
Registration Number
NCT05364255
Locations
🇬🇧

Research Site, Ruddington, United Kingdom

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