MedPath

AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Study of Relationship Between Changes in Inflammation, Lung Function, Symptoms and Medication Use in COPD Patients

Completed
Conditions
Pulmonary Disease, Chronic Obstructive
First Posted Date
2019-11-19
Last Posted Date
2022-07-20
Lead Sponsor
AstraZeneca
Target Recruit Count
31
Registration Number
NCT04168216
Locations
🇬🇧

Research Site, Oxford, Oxfordshire, United Kingdom

A Study to Assess the Reduction of Daily Maintenance ICS/LABA Treatment Towards Anti-Inflammatory Reliever Treatment in Patients With Severe Eosinophilic Asthma Treated With Benralizumab

Phase 4
Completed
Conditions
Severe Eosinophilic Asthma
Asthma
Interventions
First Posted Date
2019-11-12
Last Posted Date
2025-01-09
Lead Sponsor
AstraZeneca
Target Recruit Count
170
Registration Number
NCT04159519
Locations
🇬🇧

Research Site, Nottingham, United Kingdom

Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab.

Phase 3
Active, not recruiting
Conditions
Eosinophilic Granulomatous Vasculitis
Interventions
Biological: Placebo to Mepolizumab
Biological: Placebo to Benralizumab
First Posted Date
2019-11-08
Last Posted Date
2025-04-29
Lead Sponsor
AstraZeneca
Target Recruit Count
140
Registration Number
NCT04157348
Locations
🇬🇧

Research Site, Portsmouth, United Kingdom

Efficacy and Safety Study of Benralizumab in Patient With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps (ORCHID)

Phase 3
Active, not recruiting
Conditions
Nasal Polyposis
Interventions
Biological: Matched placebo
Biological: Benralizumab 30 mg
First Posted Date
2019-11-08
Last Posted Date
2024-05-17
Lead Sponsor
AstraZeneca
Target Recruit Count
296
Registration Number
NCT04157335
Locations
🇻🇳

Research Site, Ho Chi Minh, Vietnam

To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD8233 After Multiple Dose Administration in Subjects With Dyslipidemia

Phase 1
Completed
Conditions
Dyslipidemia
Interventions
Drug: AZD8233 subcutaneous injection
Drug: Placebo
First Posted Date
2019-11-07
Last Posted Date
2021-06-30
Lead Sponsor
AstraZeneca
Target Recruit Count
34
Registration Number
NCT04155645
Locations
🇺🇸

Research Site, Brooklyn, Maryland, United States

A Study to Understand the Safety, Tolerability, and Activity of Drug in Body Over a Period of Time of AZD2693, in Subjects of Non-Childbearing Potential in Overweight But Otherwise Healthy Subjects, and Healthy Chinese and Japanese Subjects

Phase 1
Completed
Conditions
Non-alcoholic Steatohepatitis
Metabolic Disorders
Interventions
Drug: Placebo
First Posted Date
2019-10-29
Last Posted Date
2021-11-26
Lead Sponsor
AstraZeneca
Target Recruit Count
73
Registration Number
NCT04142424
Locations
🇺🇸

Research Site, Glendale, California, United States

Study to Characterise Patients Receiving Benralizumab in the Framework of an Individualized Access Program in Spain

Completed
Conditions
Severe Eosinophilic Asthma
First Posted Date
2019-10-15
Last Posted Date
2021-06-29
Lead Sponsor
AstraZeneca
Target Recruit Count
28
Registration Number
NCT04126499
Locations
🇪🇸

BIG PAC, Madrid, Spain

US Post-Marketing Safety Study of Moxetumomab Pasudotox-tdfk (LUMOXITI)

Terminated
Conditions
Hairy Cell Leukemia
First Posted Date
2019-10-14
Last Posted Date
2023-04-21
Lead Sponsor
AstraZeneca
Target Recruit Count
2
Registration Number
NCT04125290
Locations
🇺🇸

Rocky Mountain Cancer Centers, Pueblo, Colorado, United States

🇺🇸

Research Site, Bridgeton, Missouri, United States

A Study to Evaluate the Amount of Drug That Becomes Available in the Blood Circulation When Savolitinib is Administered Alone and in Combination With Itraconazole

Phase 1
Completed
Conditions
Solid Tumour
Interventions
First Posted Date
2019-10-10
Last Posted Date
2020-01-23
Lead Sponsor
AstraZeneca
Target Recruit Count
16
Registration Number
NCT04121910
Locations
🇺🇸

Research Site, Glendale, California, United States

A Study in Healthy Subjects to Assess the Pharmacokinetics of Savolitinib When Administered Alone and in Combination With Rifampicin

Phase 1
Completed
Conditions
Solid Tumors
Interventions
First Posted Date
2019-10-08
Last Posted Date
2020-04-03
Lead Sponsor
AstraZeneca
Target Recruit Count
40
Registration Number
NCT04118842
Locations
🇺🇸

Research Site, Baltimore, Maryland, United States

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