IONIS PHARMACEUTICALS, INC.

IONIS PHARMACEUTICALS, INC. logo
🇺🇸United States
Ownership
Public, Private, Subsidiary
Established
1989-01-01
Employees
927
Market Cap
-
Website
http://www.ionis.fr

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS-MAPTRx in Patients With Mild Alzheimer's Disease

Phase 1
Completed
Conditions
Interventions
First Posted Date
2017-06-14
Last Posted Date
2023-02-27
Lead Sponsor
Ionis Pharmaceuticals, Inc.
Target Recruit Count
46
Registration Number
NCT03186989
Locations
🇸🇪

Karolinska University Hospital Huddinge, Stockholm, Sweden

🇫🇮

Clinical Research Services Turku CRST, Turku, Finland

🇬🇧

University College London Hospitals NHS Foundation Trust, London, United Kingdom

and more 10 locations

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 702843 Administered Subcutaneously to Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2017-05-24
Last Posted Date
2019-01-22
Lead Sponsor
Ionis Pharmaceuticals, Inc.
Target Recruit Count
36
Registration Number
NCT03165864
Locations
🇦🇺

Nucleus Network, Melbourne, Victoria, Australia

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ionis AGT-LRx in Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2017-04-05
Last Posted Date
2018-08-21
Lead Sponsor
Ionis Pharmaceuticals, Inc.
Target Recruit Count
62
Registration Number
NCT03101878
Locations
🇨🇦

Syneos Health, Toronto, Ontario, Canada

A Study to Evaluate the Effect of Volanesorsen on Cardiac Repolarization Conducted in Healthy Volunteers

First Posted Date
2016-09-22
Last Posted Date
2022-01-28
Lead Sponsor
Ionis Pharmaceuticals, Inc.
Target Recruit Count
52
Registration Number
NCT02910635
Locations
🇺🇸

Covance, Dallas, Texas, United States

Safety, Tolerability, PK, and Pharmacodynamics(PD) of IONIS APOCIII-LRx in Healthy Volunteers With Elevated Triglycerides

First Posted Date
2016-09-14
Last Posted Date
2018-05-22
Lead Sponsor
Ionis Pharmaceuticals, Inc.
Target Recruit Count
56
Registration Number
NCT02900027
Locations
🇨🇦

BioPharma Services, Toronto, Ontario, Canada

Study to Evaluate the Effect of ISIS GCGRRx on Hepatic Lipid and Glycogen Content in Type 2 Diabetes

Phase 2
Completed
Conditions
Interventions
First Posted Date
2016-07-06
Last Posted Date
2018-05-08
Lead Sponsor
Ionis Pharmaceuticals, Inc.
Target Recruit Count
15
Registration Number
NCT02824003
Locations
🇦🇹

Ionis Investigator Site, Vienna, Austria

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Participants With Familial Hypercholesterolemia

First Posted Date
2016-03-16
Last Posted Date
2020-11-19
Lead Sponsor
Ionis Pharmaceuticals, Inc.
Target Recruit Count
48
Registration Number
NCT02709850
Locations
🇨🇦

Clinical Site, Toronto, Ontario, Canada

Safety, Tolerability and Efficacy of ISIS-GCGRRx in Patients With Type 2 Diabetes

First Posted Date
2015-10-22
Last Posted Date
2018-06-25
Lead Sponsor
Ionis Pharmaceuticals, Inc.
Target Recruit Count
79
Registration Number
NCT02583919
Locations
🇺🇸

Ionis Investigational Site, Olympia, Washington, United States

🇺🇸

Isis Investigational Site, Spring Valley, California, United States

A Study of Safety, PK, & PD of ISIS 416858 Administered Subcutaneously to Patients With End-Stage Renal Disease on Hemodialysis

First Posted Date
2015-09-18
Last Posted Date
2016-12-13
Lead Sponsor
Ionis Pharmaceuticals, Inc.
Target Recruit Count
49
Registration Number
NCT02553889
Locations
🇨🇦

Ionis Investigative Site, Montreal, Quebec, Canada

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 443139 in Participants With Early Manifest Huntington's Disease

First Posted Date
2015-08-10
Last Posted Date
2019-05-31
Lead Sponsor
Ionis Pharmaceuticals, Inc.
Target Recruit Count
46
Registration Number
NCT02519036
Locations
🇬🇧

University College London, London, United Kingdom

🇩🇪

Ulm University Hospital, Ulm, Germany

🇬🇧

Cambridge University Hospital, Cambridge, United Kingdom

and more 6 locations
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