Vanderbilt University

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1873-01-01

Employees: 10K

Market Cap: -

Website: http://www.vanderbilt.edu

Clinical Trials

Treatment of Traumatic Brain Injury (TBI)-Related Attention Deficits in Children

Phase 4

Completed

Conditions: Traumatic Brain Injury
Attention Deficit Disorder

Interventions: Drug: Placebo
Drug: Lisdexamfetamine

First Posted Date: 2016-03-18

Last Posted Date: 2020-07-13

Lead Sponsor: Vanderbilt University

Target Recruit Count: 20

Registration Number: NCT02712996

Locations: 🇺🇸
Vanderbilt Medical Center, Nashville, Tennessee, United States

New Formulations of Propafenone to Treat Atrial Fibrillation

Phase 1

Terminated

Conditions: Atrial Fibrillation

Interventions: Drug: (R)-propafenone
Drug: Placebo
Drug: (S)-Propafenone

First Posted Date: 2016-03-17

Last Posted Date: 2022-06-03

Lead Sponsor: Vanderbilt University

Target Recruit Count: 193

Registration Number: NCT02710669

Locations: 🇺🇸
Vanderbilt University, Nashville, Tennessee, United States

Neuroinflammation and Postoperative Delirium in Cardiac Surgery

Completed

Conditions: Cardiac Surgery
Delirium

First Posted Date: 2016-02-23

Last Posted Date: 2018-09-17

Lead Sponsor: Vanderbilt University

Target Recruit Count: 630

Registration Number: NCT02688179

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Atlas Predicted DBS Settings in Essential Tremor

Not Applicable

Terminated

Conditions: Essential Tremor

Interventions: Device: Change DBS programming

First Posted Date: 2016-02-09

Last Posted Date: 2023-03-27

Lead Sponsor: Vanderbilt University

Target Recruit Count: 4

Registration Number: NCT02678429

Locations: 🇺🇸
Vanderbilt University, Nashville, Tennessee, United States

A ED-based Intervention to Improve Antihypertensive Adherence

Not Applicable

Completed

Conditions: Hypertensive Emergency
Blood Pressure
Hypertension

Interventions: Behavioral: ED usual care plus education
Behavioral: ED-based behavioral intervention

First Posted Date: 2016-02-03

Last Posted Date: 2018-08-13

Lead Sponsor: Vanderbilt University

Target Recruit Count: 220

Registration Number: NCT02672787

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Metabolic Effects of Angiotensin-(1-7)

Phase 1

Recruiting

Conditions: Hypertension
Insulin Resistance
Metabolic Cardiovascular Syndrome
Obesity

Interventions: Drug: Angiotensin-(1-7)
Drug: Saline

First Posted Date: 2016-01-05

Last Posted Date: 2024-02-01

Lead Sponsor: Vanderbilt University

Target Recruit Count: 19

Registration Number: NCT02646475

Locations: 🇺🇸
Vanderbilt University School of Medicine, Nashville, Tennessee, United States

Effect of DPP4 Inhibition on Vasoconstriction

Phase 4

Completed

Conditions: Type 2 Diabetes Mellitus

Interventions: Drug: Sitagliptin
Drug: Placebo
Drug: Valsartan 160mg
Drug: Neuropeptide Y
Drug: Enalaprilat

First Posted Date: 2015-12-24

Last Posted Date: 2018-08-27

Lead Sponsor: Vanderbilt University

Target Recruit Count: 18

Registration Number: NCT02639637

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Dysregulation of Lipid Metabolism and Right Ventricular Function in PAH

Completed

Conditions: Pulmonary Arterial Hypertension

Interventions: Procedure: Blood Sampling
Other: Cardiac MRI

First Posted Date: 2015-12-16

Last Posted Date: 2019-07-16

Lead Sponsor: Vanderbilt University

Target Recruit Count: 15

Registration Number: NCT02631421

Locations: 🇺🇸
Vanderbilt Univeristy, Nashville, Tennessee, United States

Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis

Not Applicable

Completed

Conditions: Postoperative Nausea and Vomiting

Interventions: Procedure: Automated recommendation at the start of the case
Procedure: Automated notification at the start of surgery
Procedure: Automated notification at the end of surgery
Device: Anesthesia Information Management System (AIMS)
Device: Perioperative Data Warehouse (PDW)
Procedure: General anesthesia
Procedure: Elective surgery
Drug: Propofol
Drug: Sevoflurane
Drug: Isoflurane
Drug: Desflurane
Drug: Scopolamine
Drug: Droperidol
Drug: Haloperidol
Drug: Dexamethasone
Drug: Promethazine
Drug: Meclizine
Drug: Aprepitant
Drug: Metoclopramide
Drug: Fentanyl
Drug: Sufentanil
Drug: Alfentanil
Drug: Remifentanil
Drug: Morphine
Drug: Meperidine
Drug: Hydromorphone
Drug: Methadone
Drug: Oxycodone
Drug: Oxymorphone
Drug: Hydrocodone
Drug: Ketamine
Drug: Ondansetron
Drug: Granisetron
Drug: Dolasetron mesylate
Drug: Palonosetron
Drug: Tropisetron
Drug: Ramosetron

First Posted Date: 2015-12-09

Last Posted Date: 2019-03-07

Lead Sponsor: Vanderbilt University

Target Recruit Count: 27034

Registration Number: NCT02625181

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Saline Against Lactated Ringers or Plasmalyte in the Emergency Department

Not Applicable

Completed

Conditions: Acute Kidney Injury
Critical Illness

Interventions: Other: 0.9% Saline
Other: Physiologically-balanced isotonic crystalloid

First Posted Date: 2015-11-25

Last Posted Date: 2017-09-15

Lead Sponsor: Vanderbilt University

Target Recruit Count: 14000

Registration Number: NCT02614040

Locations: 🇺🇸
Vanderbilt University Medical Center Adult Emergency Department, Nashville, Tennessee, United States

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