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Insmed

🇺🇸United States
Ownership
-
Employees
912
Market Cap
$13.2B
Website
Introduction

Insmed, Inc. is a global biopharmaceutical company, which engages in the development and commercialization of therapies for patients with rare diseases. Its focuses on Brensocatib, and Treprostinil Palmitil Inhalation Powder (TPIP) pipeline. The company was founded in 1988 and is headquartered in Bridgewater, NJ.

A Study of the Safety, Pharmacokinetics, and Pharmacodynamics of INS1007 in Healthy Japanese and Caucasian Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: Placebo
First Posted Date
2023-07-03
Last Posted Date
2023-07-03
Lead Sponsor
Insmed Incorporated
Target Recruit Count
82
Registration Number
NCT05927597
Locations
🇺🇸

USA001, Glendale, California, United States

A Study to Assess Pharmacokinetics (PK) of Brensocatib Alone and With Multiple Doses of Rifampin or Esomeprozole in Healthy Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2023-04-24
Last Posted Date
2023-08-21
Lead Sponsor
Insmed Incorporated
Target Recruit Count
32
Registration Number
NCT05826574
Locations
🇺🇸

USA001, Dallas, Texas, United States

A Study of Brensocatib Following a Single Oral Administration in Participants With or Without Renal Impairment

Phase 1
Completed
Conditions
Renal Impairment
Interventions
First Posted Date
2023-01-06
Last Posted Date
2023-04-18
Lead Sponsor
Insmed Incorporated
Target Recruit Count
28
Registration Number
NCT05673603
Locations
🇺🇸

USA003, Tampa, Florida, United States

🇺🇸

USA001, San Antonio, Texas, United States

🇺🇸

USA002, Orlando, Florida, United States

A Study of the Absorption, Metabolism, and Excretion of [14C]-Brensocatib Following a Single Oral Administration in Healthy Male Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: [14C]-brensocatib
First Posted Date
2022-12-15
Last Posted Date
2023-03-23
Lead Sponsor
Insmed Incorporated
Target Recruit Count
7
Registration Number
NCT05652257
Locations
🇺🇸

USA001, Madison, Wisconsin, United States

An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

Phase 2
Active, not recruiting
Conditions
Pulmonary Hypertension
Interstitial Lung Disease
Interventions
First Posted Date
2022-12-14
Last Posted Date
2025-04-27
Lead Sponsor
Insmed Incorporated
Target Recruit Count
31
Registration Number
NCT05649722
Locations
🇩🇪

GER010, Gießen, Hessen, Germany

🇩🇪

GER012, Berlin, Germany

🇬🇧

GBR001, Sheffield, South Yorkshire, United Kingdom

and more 19 locations

An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH)

Phase 2
Active, not recruiting
Conditions
Pulmonary Arterial Hypertension
Interventions
First Posted Date
2022-12-14
Last Posted Date
2025-04-25
Lead Sponsor
Insmed Incorporated
Target Recruit Count
91
Registration Number
NCT05649748
Locations
🇬🇧

GBR001, Bath, Avon, United Kingdom

🇷🇸

SRB003, Belgrade, Serbia

🇪🇸

ESP003, Sevilla, Spain

and more 42 locations

A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Brensocatib in Participants With Normal Hepatic Function and Participants With Hepatic Impairment

Phase 1
Completed
Conditions
Hepatic Impairment
Interventions
First Posted Date
2022-08-26
Last Posted Date
2023-07-19
Lead Sponsor
Insmed Incorporated
Target Recruit Count
30
Registration Number
NCT05517525
Locations
🇺🇸

USA002, Rialto, California, United States

🇺🇸

USA003, Orlando, Florida, United States

🇺🇸

USA001, San Antonio, Texas, United States

A Study to Investigate the Effects of Brensocatib on QT Interval in Healthy Participants

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2022-05-02
Last Posted Date
2023-03-27
Lead Sponsor
Insmed Incorporated
Target Recruit Count
48
Registration Number
NCT05355935
Locations
🇺🇸

USA001, Madison, Wisconsin, United States

An Expanded Access Study to Assess Brensocatib for Participants With Non-Cystic Fibrosis Bronchiectasis

Conditions
Non-Cystic Fibrosis Bronchiectasis
First Posted Date
2022-04-25
Last Posted Date
2025-02-28
Lead Sponsor
Insmed Incorporated
Registration Number
NCT05344508

A Study to Evaluate the Safety and Tolerability of Treprostinil Palmitil Inhalation Powder in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease

Phase 2
Completed
Conditions
Pulmonary Hypertension
Interventions
First Posted Date
2022-01-04
Last Posted Date
2025-03-17
Lead Sponsor
Insmed Incorporated
Target Recruit Count
39
Registration Number
NCT05176951
Locations
🇦🇺

AUS003, Camperdown, New South Wales, Australia

🇦🇺

AUS005, Macquarie Park, New South Wales, Australia

🇧🇪

BEL002, Liège, Belgium

and more 22 locations
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