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Roche Holding AG

Roche Holding AG logo
πŸ‡¨πŸ‡­Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Bioavailability and Pharmacokinetic Study of Subcutaneous and Intravenous RO6811135 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2013-03-01
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
12
Registration Number
NCT01802853

A Study of Alectinib (RO5424802) in Participants With Non-Small Cell Lung Cancer Who Have Anaplastic Lymphoma Kinase (ALK) Mutation and Failed Crizotinib Treatment

Phase 1
Completed
Conditions
Non-Small-Cell Lung Carcinoma
Interventions
First Posted Date
2013-02-28
Last Posted Date
2018-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
138
Registration Number
NCT01801111
Locations
πŸ‡ΊπŸ‡Έ

Rush University Medical Center, Chicago, Illinois, United States

πŸ‡ΊπŸ‡Έ

UCLA Cancer Center; Premiere Oncology, A Medical Corporation, Santa Monica, California, United States

πŸ‡ΊπŸ‡Έ

Washington University; Wash Uni. Sch. Of Med, Saint Louis, Missouri, United States

and more 81 locations

An Observational Study of Pegasys (Peginterferon Alfa-2a) Plus Ribavirin Based Regimens in Patients With Chronic Hepatitis C With Previous Treatment Failure

Terminated
Conditions
Hepatitis C, Chronic
Interventions
First Posted Date
2013-02-26
Last Posted Date
2016-09-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
282
Registration Number
NCT01798576

An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis B Who Have Failed Antiviral Treatment With Nucleoside (Nucleotide) Analogues

Terminated
Conditions
Hepatitis B, Chronic
First Posted Date
2013-02-18
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
44
Registration Number
NCT01794234

A Study of RG7314 to Investigate Efficacy and Safety in Individuals With Autism Spectrum Disorders (ASD)

Phase 2
Completed
Conditions
Autism Spectrum Disorder
Interventions
Drug: Placebo
First Posted Date
2013-02-15
Last Posted Date
2017-02-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
223
Registration Number
NCT01793441
Locations
πŸ‡ΊπŸ‡Έ

Neuroscientific Insights, Rockville, Maryland, United States

πŸ‡ΊπŸ‡Έ

University of California Davis, Sacramento, California, United States

πŸ‡ΊπŸ‡Έ

Montefiore Medical Center; Departments of Psychiatry & Biobehavioral Science, Bronx, New York, United States

and more 24 locations

An Efficacy and Safety Study of Tocilizumab (RoActemra/Actemra) in Participants With Giant Cell Arteritis (GCA)

Phase 3
Completed
Conditions
Giant Cell Arteritis
Interventions
First Posted Date
2013-02-13
Last Posted Date
2020-02-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
251
Registration Number
NCT01791153
Locations
πŸ‡ΊπŸ‡Έ

Univ of Calif., Los Angeles; Rheumatology, Los Angeles, California, United States

πŸ‡ΊπŸ‡Έ

Cedars-Sinai Medical Center, Los Angeles, California, United States

πŸ‡ΊπŸ‡Έ

Rheumatology Assoc. of S. Florida - Clinical Research Center, Boca Raton, Florida, United States

and more 75 locations

BEVERLY-C: An Observational Study of Avastin (Bevacizumab) in First-Line Treatment in Elderly Patients With Metastatic Colorectal Cancer

Completed
Conditions
Colorectal Cancer
First Posted Date
2013-02-13
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
3
Registration Number
NCT01791140

An Observational Study of Tarceva (Erlotinib) in First Line in Patients With Advanced EGFR Mutation-Positive Non-Small Cell Lung Cancer (GERTAC)

Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
First Posted Date
2013-02-13
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
52
Registration Number
NCT01790217

A Safety, Pharmacokinetics and Pharmacodynamics Study of RO6811135 in Patients With Type 2 Diabetes Mellitus

Phase 1
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
Drug: Placebo
First Posted Date
2013-02-12
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
56
Registration Number
NCT01789788
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