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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Study of A High Concentration Liquid Formulation Versus A Lyophilized Formulation of Gantenerumab in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-07-10
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
120
Registration Number
NCT01636531

A Study of Bitopertin (RO4917838) in Healthy Male Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: bitopertin
Drug: placebo
First Posted Date
2012-07-10
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
71
Registration Number
NCT01636492

A Study of RO5045337 in Combination With Cytarabine in Patients With Acute Myelogenous Leukemia

Phase 1
Completed
Conditions
Myelogenous Leukemia, Acute
Interventions
Drug: RO5045377
Drug: cytarabine
First Posted Date
2012-07-09
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
43
Registration Number
NCT01635296

An Non-Interventional Study of Patients With Persistent Symptoms of Schizophrenia

Completed
Conditions
Schizophrenia
First Posted Date
2012-07-06
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1433
Registration Number
NCT01634542

A Study of Onartuzumab (MetMAb) in Combination With Bevacizumab Compared to Bevacizumab Alone or Onartuzumab Monotherapy in Participants With Recurrent Glioblastoma

Phase 2
Completed
Conditions
Glioblastoma
Interventions
First Posted Date
2012-07-02
Last Posted Date
2018-02-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
135
Registration Number
NCT01632228
Locations
🇩🇪

Ärztehaus Velen, Ibbenbühren, Germany

🇨🇦

McGill University; Montreal Neurological Institute; Oncology, Montreal, Quebec, Canada

🇨🇦

London Health Sciences Centre, London, Ontario, Canada

and more 59 locations

A Single Dose Study of Radiolabeled RO4602522 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: RO4602522
First Posted Date
2012-06-29
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
6
Registration Number
NCT01631422

A Study of the Effect of Carbamazepine on the Pharmacokinetics of RO4917523 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Carbamazepine
Drug: RO4917523
First Posted Date
2012-06-27
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
16
Registration Number
NCT01629368

ANNAPURNA: A Study of The Combination of RO5466731, RO5190591, Ritonavir and Copegus (Ribavirin) With or Without RO5024048 in Patients With Chronic Hepatitis C Who Are Either Treatment-Naïve or Have Previously Experienced a Null Response to Interferon-Based Treatment

Phase 2
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: RO5024048
Drug: RO5190591
Drug: RO5466731
Drug: ribavirin [Copegus]
Drug: ritonavir
First Posted Date
2012-06-26
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
110
Registration Number
NCT01628094

A Study of The Effects of Multiple Doses of Ketoconazole on Single Dose Pharmacokinetics of RO4602522 in Healthy Male Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: RO4602522
Drug: ketoconazole
First Posted Date
2012-06-21
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
34
Registration Number
NCT01625806

A Single-Ascending-Dose Study of RO5469754 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: RO5469754
Drug: Placebo
First Posted Date
2012-06-15
Last Posted Date
2013-02-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
36
Registration Number
NCT01620931
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