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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

An Observational Study of Adjuvant Treatment With Capecitabine (Xeloda) in Combination With Oxaliplatin in Participants With Stage III Colon Cancer

Completed
Conditions
Colorectal Cancer
Interventions
Drug: Capecitabine
Biological: Oxaliplatin
First Posted Date
2011-09-28
Last Posted Date
2016-07-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
74
Registration Number
NCT01442155

A Study of The Abuse Liability Potential of RO4917838 in Recreational Drug Users

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: RO4917838
Drug: diazepam
Drug: Placebo
First Posted Date
2011-09-22
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
177
Registration Number
NCT01438749

MARIGOLD Study: A Study of RO4917523 Versus Placebo as Adjunctive Therapy in Patients With Major Depressive Disorder and an Inadequate Response to Ongoing Antidepressant Therapy

Phase 2
Completed
Conditions
Major Depressive Disorder
Interventions
Drug: Placebo
Drug: RO4917523 1.5 mg
Drug: RO4917523 0.5 mg
First Posted Date
2011-09-21
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
319
Registration Number
NCT01437657

A Study of RG1662 in Individuals With Down Syndrome

Phase 1
Completed
Conditions
Down Syndrome
Interventions
Drug: Placebo
Drug: RG1662
First Posted Date
2011-09-20
Last Posted Date
2015-03-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
35
Registration Number
NCT01436955

A Pharmacokinetic Study of RO4917838 in Healthy Chinese Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: RO4917838
First Posted Date
2011-09-14
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
16
Registration Number
NCT01433575

A Study Evaluating Slow Response/Non-Rapid Response in Patients With Chronic Hepatitis C, Genotype 1, 2, 3 & 4 Treated With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin)

Phase 4
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
Drug: ribavirin [Copegus]
First Posted Date
2011-09-07
Last Posted Date
2018-10-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1013
Registration Number
NCT01429792
Locations
🇮🇱

Holy Family Medical Center; Gastroenterology, Nazareth, Israel

🇮🇱

Chaim Sheba Medical Center; Gastroenterology, Ramat Gan, Israel

🇮🇱

Maccabi Health Services MC, Tel Aviv, Israel

and more 23 locations

An Observational Study of Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) as Maintenance Treatment in Patients With Chronic Renal Anemia on Haemodialysis

Completed
Conditions
Anemia, Kidney Disease, Chronic
First Posted Date
2011-08-24
Last Posted Date
2016-03-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
185
Registration Number
NCT01422824

A Study of Trastuzumab Emtansine in Comparison With Treatment of Physician's Choice in Participants With HER2-positive Breast Cancer Who Have Received at Least Two Prior Regimens of HER2-directed Therapy

Phase 3
Completed
Conditions
Breast Cancer
Interventions
Drug: Trastuzumab emtansine
Drug: Treatment of physician's choice
First Posted Date
2011-08-18
Last Posted Date
2016-10-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
602
Registration Number
NCT01419197

A Study to Evaluate the Effect of Danoprevir/Ritonavir on the Pharmacokinetics of Escitalopram and S-Demethylcitalopram in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2011-08-17
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
20
Registration Number
NCT01418274

A Study of RO5285119 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: RO5285119
Drug: placebo
First Posted Date
2011-08-17
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
77
Registration Number
NCT01418963
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