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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

AVAPERL1 Study: A Study of Avastin (Bevacizumab) With or Without Pemetrexed as Maintenance Therapy After Avastin in First Line in Patients With Non-Squamous Non-Small Cell Lung Cancer

Phase 3
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2009-08-19
Last Posted Date
2016-02-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
376
Registration Number
NCT00961415

A Study of Tocilizumab + DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: tocilizumab [RoActemra/Actemra]
Drug: Standard DMARDs (Disease Modifying Anti Rheumatic Drugs)
First Posted Date
2009-08-04
Last Posted Date
2017-08-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
105
Registration Number
NCT00951275
Locations
🇮🇹

Policlinico Tor Vergata; Divisione Di Reumatologia, Roma, Lazio, Italy

🇮🇹

Ospedale San Paolo; Divisione di Reumatologia, Savona, Liguria, Italy

🇮🇹

Az. Ospedaliera Univ. di Parma; Medicina Interna e Reumatologia, Parma, Emilia-Romagna, Italy

and more 24 locations

An Expanded Access Program of Tarceva (Erlotinib) in Participants With Advanced Non-Small Cell Lung Cancer (NSCLC)

Phase 4
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2009-07-31
Last Posted Date
2016-10-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
6586
Registration Number
NCT00949910

A Study to Compare Subcutaneous (SC) Versus Intravenous (IV) Administration of Herceptin (Trastuzumab) in Women With Human Epidermal Growth Factor Receptor (HER) 2-Positive Early Breast Cancer

First Posted Date
2009-07-31
Last Posted Date
2018-01-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
596
Registration Number
NCT00950300
Locations
🇦🇷

Centro Medico San Roque; Oncology Dept, Tucuman, Argentina

🇭🇺

Szegedi Tudomanyegyetem, AOK, Szent-Gyorgyi Albert Klinikai Kozpont, Onkoterapias Klinika, Szeged, Hungary

🇲🇽

Hospital Privado San Jose; Oncologia, Obregon, Mexico

and more 103 locations

A Study of Vemurafenib in Previously Treated Patients With Metastatic Melanoma

Phase 2
Completed
Conditions
Malignant Melanoma
Interventions
First Posted Date
2009-07-30
Last Posted Date
2017-07-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
132
Registration Number
NCT00949702
Locations
🇺🇸

University of Pittsburgh, Pittsburgh, Pennsylvania, United States

🇺🇸

University of Colorado, Denver, Colorado, United States

🇺🇸

UCLA - School of Medicine; Division of Hematology/Oncology, Los Angeles, California, United States

and more 12 locations

A Study on Emergence of Resistance With Oseltamivir (Tamiflu) in Participants With Seasonal Influenza

Phase 3
Completed
Conditions
Influenza
Interventions
First Posted Date
2009-07-30
Last Posted Date
2016-08-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
37
Registration Number
NCT00949533

A Study of Bevacizumab (Avastin®) in Combination With Temozolomide and Radiotherapy in Participants With Newly Diagnosed Glioblastoma

Phase 3
Completed
Conditions
Glioblastoma
Interventions
Drug: Bevacizumab
Drug: Temozolomide
Radiation: Radiation therapy
Drug: Placebo
First Posted Date
2009-07-22
Last Posted Date
2017-09-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
921
Registration Number
NCT00943826
Locations
🇧🇪

CHU Sart-Tilman, Liège, Belgium

🇺🇸

University of Virgina, Charlottesville, Virginia, United States

🇫🇷

Centre Georges François Leclerc, Dijon, France

and more 130 locations

A Study of Xenical (Orlistat) in Overweight and Obese Adolescents

Phase 3
Completed
Conditions
Obesity
Interventions
Behavioral: Diet and Exercise
Drug: orlistat [Xenical]
First Posted Date
2009-07-16
Last Posted Date
2016-04-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
60
Registration Number
NCT00940628

OPAL Study: A Study of Avastin (Bevacizumab) in Combination With FOLFOXIRI in Patients With Previously Untreated Metastatic Colorectal Cancer

First Posted Date
2009-07-16
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
97
Registration Number
NCT00940303

A Study of Combination Treatment With Pegasys (Peginterferon Alfa) and Copegus (Ribavirin)in Patients With Chronic Hepatitis C

Phase 4
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: Copegus (ribavirin)
Drug: peginterferon alfa-2a [Pegasys]
First Posted Date
2009-07-16
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
2695
Registration Number
NCT00940420
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