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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Continuation Study of Herceptin (Trastuzumab) in Participants With Metastatic or Locally Advanced Cancer

Phase 3
Completed
Conditions
Neoplasms
Interventions
First Posted Date
2016-03-29
Last Posted Date
2017-03-31
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
69
Registration Number
NCT02721641

Efficacy and Safety Study of RoActemra (Tocilizumab) in Participants With Rheumatoid Arthritis

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2016-03-28
Last Posted Date
2016-07-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
592
Registration Number
NCT02721004

A Study of Ocrelizumab in Participants With Moderate to Severe Rheumatoid Arthritis (RA)

Phase 1
Terminated
Conditions
Rheumatoid Arthritis
Interventions
Drug: Placebo
Drug: Ocrelizumab
First Posted Date
2016-03-25
Last Posted Date
2016-03-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
175
Registration Number
NCT02720120

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics (PK) of Oseltamivir and Its Carboxylate Metabolite, RO0640802 in Healthy Participants

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
Drug: Oseltamivir
First Posted Date
2016-03-24
Last Posted Date
2016-06-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
99
Registration Number
NCT02717754

A Study to Evaluate Renal Safety of Intravenous Ibandronate (Bondronat) in Participants With Metastatic Bone Disease Due to Breast Cancer

Phase 3
Completed
Conditions
Pain; Bone Neoplasms; Neoplasm Metastasis
Interventions
First Posted Date
2016-03-23
Last Posted Date
2016-03-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
334
Registration Number
NCT02716792

Influence of Ribavirin on the Initial Virological Response in Treatment Naïve Patients With Hepatitis C Genotype 1 Infection

Phase 2
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: Pegylated Interferon (PEG-IFN) alfa-2a
Drug: Placebo
Drug: Ribavirin
First Posted Date
2016-03-23
Last Posted Date
2016-08-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
68
Registration Number
NCT02716779

A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors

First Posted Date
2016-03-22
Last Posted Date
2021-07-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
243
Registration Number
NCT02715531
Locations
🇺🇸

Stanford Cancer Institute; Hematology, Palo Alto, California, United States

🇺🇸

Georgetown University Medical Center, Washington, District of Columbia, United States

🇺🇸

Columbia University Medical Center, New York, New York, United States

and more 27 locations

A Single-Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics (PK) of Gantenerumab Following Subcutaneous (SC) Administration in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
Drug: Gantenerumab
First Posted Date
2016-03-17
Last Posted Date
2019-04-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
18
Registration Number
NCT02711423
Locations
🇺🇸

Bioclinica Research, Orlando, Florida, United States

Utility Study in Diffuse Large B-Cell Lymphoma (DLBCL)

Completed
Conditions
Diffuse Large B-Cell Lymphoma
First Posted Date
2016-03-15
Last Posted Date
2017-04-20
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
91
Registration Number
NCT02708732
Locations
🇬🇧

PH Associates - an OPen Health Company, Marlow, United Kingdom

A Study to Assess the Safety and Tolerability of N-Acetylcysteine When Administered With Pirfenidone to Participants With Idiopathic Pulmonary Fibrosis (IPF)

Phase 2
Completed
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
First Posted Date
2016-03-14
Last Posted Date
2016-05-20
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
123
Registration Number
NCT02707640
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