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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Study of Idasanutlin With Cytarabine Versus Cytarabine Plus Placebo in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)

Phase 3
Terminated
Conditions
Leukemia, Myeloid, Acute
Interventions
First Posted Date
2015-09-09
Last Posted Date
2022-01-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
447
Registration Number
NCT02545283
Locations
🇫🇷

Hopital Claude Huriez; Hematologie, Lille, France

🇫🇷

Institut J Paoli I Calmettes; Onco Hematologie 2, Marseille, France

🇫🇷

Hopital Saint Louis; Oncologie Medicale, Paris, France

and more 79 locations

Avastin (Bevacizumab) in the Treatment of Metastatic Colorectal Cancer in Normal Clinical Use in the UK Population

Withdrawn
Conditions
Metastatic Colorectal Cancer
Interventions
Other: No intervention
First Posted Date
2015-09-07
Last Posted Date
2017-09-13
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT02542436

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Preliminary Efficacy of Atezolizumab (Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) in Pediatric and Young Adult Participants With Solid Tumors

Phase 1
Terminated
Conditions
Solid Tumor
Interventions
First Posted Date
2015-09-04
Last Posted Date
2020-02-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
87
Registration Number
NCT02541604
Locations
🇨🇭

Universitäts-Kinderspital; Abteilung für Onkologie, Zürich, Switzerland

🇮🇹

Azienda Ospedaliera di Padova; Clinica di Onco-ematologia pediatrica, Padova, Veneto, Italy

🇪🇸

Hospital Sant Joan De Deu, Esplugues De Llobregas, Barcelona, Spain

and more 27 locations

Observational Study of MIRCERA in Users of Self-Application and Multidose Systems

Completed
Conditions
Renal Anemia of Chronic Kidney Disease
Interventions
Device: MIRCERA
First Posted Date
2015-09-03
Last Posted Date
2015-12-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
240
Registration Number
NCT02540213

An Observational Study of Methoxy Polyethylene Glycol-epoetin Beta in Participants With a Kidney Transplant

Completed
Conditions
Anemia, Kidney Transplantation
Interventions
Drug: Methoxy-polyethyleneglycol epoetin beta
First Posted Date
2015-09-02
Last Posted Date
2017-06-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
290
Registration Number
NCT02538107
Locations
🇩🇪

Klinikum Hann. Münden, Nephrologisches Zentrum Niedersachsen, Hann. Münden, Germany

Longitudinal Cohort Study in Participants With Severe Asthma to Assess Biomarkers

Phase 4
Completed
Conditions
Asthma
Interventions
Drug: FP
Drug: LABA
Drug: LTRA
Drug: LAMA
Drug: Theophylline
Drug: Oral Corticosteroids
First Posted Date
2015-09-02
Last Posted Date
2019-04-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
483
Registration Number
NCT02537691
Locations
🇱🇻

Riga 1st hospital, outpatient clinic Bruninieks, Riga, Latvia

🇱🇻

Clinical Hospital Gailezers; Dept of Pulmonology, Riga, Latvia

🇱🇻

Latvian University postgraduate institute, Riga, Latvia

and more 97 locations

Human Epidermal Growth Factor Receptor 2 (HER2) Advanced Gastric Epidemiology Study in Korea

Completed
Conditions
Gastric Cancer
Gastroesophageal Junction Cancer
First Posted Date
2015-09-02
Last Posted Date
2017-07-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1695
Registration Number
NCT02538562
Locations
🇰🇷

Chonbuk National Uni Hospital, Jeollabuk-do, Korea, Republic of

🇰🇷

Inje university Haeundae Paik Hospital, Busan, Korea, Republic of

🇰🇷

Inje University Busan Paik Hospital, Busan, Korea, Republic of

and more 11 locations

Non-Interventional Study to Examine Rituximab Treatment in Follicular Lymphoma Participants

Completed
Conditions
Follicular Lymphoma
Interventions
First Posted Date
2015-09-01
Last Posted Date
2023-04-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
505
Registration Number
NCT02536664

An Observational Study on Human Epidermal Growth Factor Receptor (HER) 2 Status of Breast Invasive Carcinoma in Latin American Participants

Completed
Conditions
Breast Cancer
First Posted Date
2015-08-28
Last Posted Date
2017-04-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
580
Registration Number
NCT02535026

A Phase IV Study to Evaluate the Effect of Subcutaneous (SC) Tocilizumab Administered to Participants With Rheumatoid Arthritis (RA) Assessed Using Disease Activity Score (DAS28)

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2015-08-27
Last Posted Date
2018-02-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
60
Registration Number
NCT02534311
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