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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Study of Pertuzumab With Erlotinib in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Phase 1
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2015-07-23
Last Posted Date
2015-10-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
17
Registration Number
NCT02507375

Effect of RO6871765 and RO7011785 on Immune Response With the Stimulation of Peripheral Blood Mononuclear Cells (PBMCs) in Chinese Healthy Volunteers and Chronic Hepatitis B Patients

Terminated
Conditions
Hepatitis B, Chronic
First Posted Date
2015-07-15
Last Posted Date
2016-11-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
14
Registration Number
NCT02498275

A Phase Ib, Open-label, Multicenter Study of the Safety and PK of the Combination of rhuMAb2c4 (Omnitarg), a Recombinant Humanized Antibody to HER2, and Capecitabine (Xeloda) in Patients With Advanced Solid Tumors

Phase 1
Completed
Conditions
Solid Tumor
Interventions
Drug: Capecitabine
Drug: RhuMab 2C4
First Posted Date
2015-07-10
Last Posted Date
2015-11-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
19
Registration Number
NCT02494596

A Study of Pertuzumab in Participants With Metastatic Breast Cancer

Phase 2
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2015-07-08
Last Posted Date
2015-08-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
79
Registration Number
NCT02491892

A Multiple-Dose Study of RhuMab 2C4 and Docetaxel in the Treatment of Advanced Solid Tumors

Phase 1
Completed
Conditions
Solid Tumor
Interventions
Drug: Docetaxel
Drug: RhuMab 2C4
First Posted Date
2015-07-03
Last Posted Date
2017-05-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
19
Registration Number
NCT02490475

A Study Of Mircera In Patients With Kidney Disease Who Are Not On Dialysis

Completed
Conditions
Renal Tubular Acidosis, Distal, With Hemolytic Anemia
Interventions
Other: No intervention
First Posted Date
2015-07-03
Last Posted Date
2015-08-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
153
Registration Number
NCT02490514

An Extension Study of Onartuzumab in Participants With Solid Tumors on Study Treatment Previously Enrolled in a Company Sponsored Study

Phase 3
Completed
Conditions
Solid Tumor
Interventions
First Posted Date
2015-07-02
Last Posted Date
2019-07-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
12
Registration Number
NCT02488330
Locations
🇫🇷

Hopital Roger Salengro, Lille, France

🇯🇵

National Hospital Organization Shikoku Cancer Center, Ehime, Japan

🇮🇹

Azienda Ospedaliero Universitaria San Giovanni Battista Di Torino, Torino, Piemonte, Italy

and more 7 locations

MabThera (Rituximab) in Combination With CHOP (or CHOP-like) Chemotherapy in Patients With Aggressive B-Cell Lymphoma

Completed
Conditions
Lymphoma, Lymphoma, Large B-Cell, Diffuse, Non-Hodgkin's Lymphoma, Lymphoma, Non Hodgkin, Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Interventions
First Posted Date
2015-07-01
Last Posted Date
2016-02-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
154
Registration Number
NCT02486952

Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With Lung Cancer [IMpower010]

Phase 3
Active, not recruiting
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2015-07-01
Last Posted Date
2024-08-20
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1280
Registration Number
NCT02486718
Locations
🇪🇸

Hospital NisA 9 de Octubre, Valencia, Spain

🇨🇳

Zhejiang Cancer Hospital, Zhejiang, China

🇫🇷

Hôpital Universitaire Dupuytren, Limoges, France

and more 225 locations

Study for Validation of Standardized Questionnaires on Depression and Investigation of the Frequency of Depression in Rheumatoid Arthritis (RA) Participants

Completed
Conditions
Rheumatoid Arthritis
First Posted Date
2015-06-30
Last Posted Date
2016-10-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1292
Registration Number
NCT02485483
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