Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products

First Posted Date
2022-07-27
Last Posted Date
2024-12-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
5000
Registration Number
NCT05476926
Locations
🇨🇱

Centro de la Vision, Las Condes, Chile

🇩🇪

Universitaetsklinikum Jena, Jena, Germany

🇩🇪

Universitaetsklinikum Koeln, Koeln, Germany

and more 239 locations

A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (Morpheus-Head and Neck Cancer)

First Posted Date
2022-07-14
Last Posted Date
2024-08-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
12
Registration Number
NCT05459129
Locations
🇺🇸

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States

🇦🇺

Sir Charles Gairdner Hospital; Medical Oncology, Perth, Western Australia, Australia

🇫🇷

Institut de Cancérologie de Lorraine, Vandoeuvre-Les-Nancy, France

and more 14 locations

Screening Study for Participants With Malignant Tumors

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2022-06-15
Last Posted Date
2024-12-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
15000
Registration Number
NCT05419375
Locations
🇫🇷

CHU Angers, Service de Pneumologie, Angers, France

🇫🇷

CHU Strasbourg - Nouvel Hopital Civil, Strasbourg, France

🇫🇷

HIA Sainte Anne - Toulon, Toulon, France

and more 134 locations

A Study of Multiple Doses of RO7247669 in Participants With Previously Untreated Unresectable or Metastatic Melanoma

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2022-06-15
Last Posted Date
2024-11-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
80
Registration Number
NCT05419388
Locations
🇨🇿

Masarykuv onkologicky ustav, Brno, Czechia

🇦🇺

Coffs Harbour Health Campus, Coffs Harbour, New South Wales, Australia

🇦🇺

Melanoma Institute Australia, North Sydney, New South Wales, Australia

and more 27 locations

A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer

First Posted Date
2022-06-13
Last Posted Date
2024-10-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
347
Registration Number
NCT05415215
Locations
🇧🇦

University Clinical Center of the Republic of Srpska, Banja Luka, Bosnia and Herzegovina

🇨🇷

Clinica CIMCA, San José, Costa Rica

🇵🇪

Instituto Regional de Enfermedades Neoplásicas del Sur; Centro de Inv. de Medicina Oncológica, Arequipa, Peru

and more 42 locations

Study To Evaluate The Efficacy And Safety Of Balovaptan In Adults With Post-Traumatic Stress Disorder (PTSD)

First Posted Date
2022-06-02
Last Posted Date
2024-04-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
29
Registration Number
NCT05401565
Locations
🇺🇸

CITrials, Inc., Bellflower, California, United States

🇺🇸

ASCLEPES Research Centers, Panorama City, California, United States

🇺🇸

Clinical Innovations, Inc, Santa Ana, California, United States

and more 12 locations

Study to Evaluate The Safety and Efficacy of Balovaptan in Participants With Acute Ischemic Stroke at a High Risk of Developing Malignant Brain Edema

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2022-06-01
Last Posted Date
2023-08-07
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT05399550
Locations
🇺🇸

CPMC Comprehensive Stroke Care Center, San Francisco, California, United States

A Study Evaluating the Efficacy, Safety, and Pharmacokinetics of Glofitamab in Combination With Rituximab Plus Ifosfamide, Carboplatin Etoposide Phosphate in Participants With Relapsed/Refractory Transplant or CAR-T Therapy Eligible Diffuse B-Cell Lymphoma

First Posted Date
2022-05-06
Last Posted Date
2024-12-19
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
40
Registration Number
NCT05364424
Locations
🇺🇸

Chao Family Comprehensive Cancer Center UCI, Orange, California, United States

🇺🇸

Memorial Cancer Institute at Memorial West, Pembroke Pines, Florida, United States

🇺🇸

The University of Chicago, Chicago, Illinois, United States

and more 6 locations

An Open-Label, Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab in Combination With Tiragolumab With or Without Atezolizumab in Participants With B-Cell Non-Hodgkin Lymphoma

First Posted Date
2022-04-07
Last Posted Date
2024-10-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
8
Registration Number
NCT05315713
Locations
🇧🇪

Institut Jules Bordet, Bruxelles, Belgium

🇧🇪

CHU UCL Namur - Mont-Godinne, Yvoir, Belgium

🇩🇪

Universitaet Duisburg-Essen, Essen, Germany

and more 14 locations

A Study to Evaluate the Safety and Efficacy of Basmisanil Treatment in Children Aged 2-14 Years With Dup15q Syndrome

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2022-04-01
Last Posted Date
2024-07-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
7
Registration Number
NCT05307679
Locations
🇺🇸

Rush University Medical Center, Chicago, Illinois, United States

🇺🇸

Rady Children's Hospital - San Diego, San Diego, California, United States

🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

and more 8 locations
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