DeepMed Research

University Health Network

🇨🇦Canada

Country: 🇨🇦Canada

Ownership: Private

Established: 1999-01-01

Employees: 10K

Market Cap: -

Website: http://www.uhn.ca

Clinical Trials

Efficacy, Mechanisms and Safety of SGLT2 Inhibitors in Kidney Transplant Recipients

Phase 3

Completed

Conditions: Kidney Transplant Recipients
Post-transplant Diabetes Mellitus
Type 2 Diabetes

Interventions: Drug: Placebo Matching Dapagliflozin Oral Tablet
Drug: Dapagliflozin 10 MG Oral Tablet

First Posted Date: 2021-07-16

Last Posted Date: 2025-03-20

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 52

Registration Number: NCT04965935

Locations: 🇨🇦
Renal Physiology Laboratory, Toronto, Ontario, Canada

Feasibility of a Home Exercise Program to Manage Post-transplant Metabolic Syndrome

Not Applicable

Completed

Conditions: Metabolic Syndrome

Interventions: Behavioral: Exercise Training

First Posted Date: 2021-07-16

Last Posted Date: 2024-11-26

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 26

Registration Number: NCT04965142

Locations: 🇨🇦
University Health Network - Toronto General Hospital, Toronto, Ontario, Canada

Anesthesia Induced Brain Cancer Survival (ABC Survival): A Feasibility Study

Not Applicable

Recruiting

Conditions: Anesthesia
Brain Cancer
Survival

Interventions: Drug: Propofol group
Drug: Sevoflurane group

First Posted Date: 2021-07-15

Last Posted Date: 2025-01-31

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 40

Registration Number: NCT04962672

Locations: 🇨🇦
Toronto Western Hospital/UHN, Toronto, Ontario, Canada

RESTORE in Patients Who Had COVID-19 and Close Others

Not Applicable

Conditions: Mental Health
Anxiety
Depressive Symptoms
PTSD

First Posted Date: 2021-07-12

Last Posted Date: 2021-11-05

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 20

Registration Number: NCT04958902

Locations: 🇨🇦
University Health Network, Toronto, Ontario, Canada

BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial

Not Applicable

Recruiting

Conditions: Brain Neoplasms
Liquid Biopsy

Interventions: Procedure: Magnetic Resonance Guided Focused Ultrasound Tumor Ablation and Liquid Biopsy Acquisition
Procedure: Magnetic Resonance Guided Focused Ultrasound Thalamotomy

First Posted Date: 2021-06-25

Last Posted Date: 2023-07-27

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 50

Registration Number: NCT04940507

Locations: 🇨🇦
Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada

Decidual Stromal Cells to Treat Graft-vs-Host Disease After Stem Cell Transplant for Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Phase 2

Completed

Conditions: Steroid Refractory GVHD
Myelodysplastic/Myeloproliferative Neoplasm
Allogeneic Hematopoietic Cell Transplant

Interventions: Biological: Decidual stromal cells (DSC)

First Posted Date: 2021-06-15

Last Posted Date: 2023-01-10

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 1

Registration Number: NCT04926194

Locations: 🇨🇦
Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Pharmacological Mechanisms of Low-intensity Focused Ultrasound for Motor Cortex Neuroplasticity

Early Phase 1

Recruiting

Conditions: Low Intensity Focussed Ultrasound

Interventions: Drug: Carbamazepine
Drug: Lorazepam
Drug: Dextromethorphan
Drug: Nimodipine
Drug: Placebo

First Posted Date: 2021-06-11

Last Posted Date: 2022-05-25

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 20

Registration Number: NCT04923659

Locations: 🇨🇦
Toronto Western Hospital, Toronto, Ontario, Canada

Time-effect of FEST+TST in the Upper-extremity Rehabilitation of Individuals with Traumatic SCI

Not Applicable

Not yet recruiting

Conditions: Spinal Cord Injuries

Interventions: Other: FES Therapy combined with task-specific training (FEST+TST)

First Posted Date: 2021-06-02

Last Posted Date: 2024-12-06

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 18

Registration Number: NCT04910204

Locations: 🇨🇦
Lyndhurst Centre, KITE - TRI UHN, Toronto, Ontario, Canada

PET/MR Pre- and Post Radiotherapy for Cardiopulmonary Dysfunction Evaluation

Not Applicable

Recruiting

Conditions: Pulmonary Hypertension

Interventions: Drug: PET/MR with 18F-FDG

First Posted Date: 2021-05-26

Last Posted Date: 2024-08-27

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 40

Registration Number: NCT04901884

Locations: 🇨🇦
University Health Network, Toronto, Ontario, Canada

Implementation and Evaluation of a Stepped-Care Mental Health Treatment Program for Patients With Chronic Pain

Active, not recruiting

Conditions: Chronic Pain

First Posted Date: 2021-05-13

Last Posted Date: 2024-04-18

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 70

Registration Number: NCT04885192

Locations: 🇨🇦
University Health Network- Toronto General Hospital, Toronto, Ontario, Canada

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