University Health Network

🇨🇦Canada

Country: 🇨🇦Canada

Ownership: Private

Established: 1999-01-01

Employees: 10K

Market Cap: -

Website: http://www.uhn.ca

Clinical Trials

CBF and NCF Changes With Brain Radiation

Recruiting

Conditions: Neurocognitive Dysfunction
Brain Metastases

Interventions: Radiation: WBRT and neurocognitive assessments
Radiation: SRS and neurocognitive assessments

First Posted Date: 2018-07-30

Last Posted Date: 2024-06-18

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 110

Registration Number: NCT03606421

Locations: 🇨🇦
University Health Network, Toronto, Ontario, Canada

Assessing Lung Inhomogeneity During Ventilation for Acute Hypoxemic Respiratory Failure

Not Applicable

Completed

Conditions: Acute Respiratory Distress Syndrome
Hypoxemic Respiratory Failure
Mechanical Ventilation Pressure High

Interventions: Other: ExPRESS-derived PEEP level
Device: Electrical Impedance Tomography

First Posted Date: 2018-07-18

Last Posted Date: 2023-11-21

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 20

Registration Number: NCT03589482

Locations: 🇨🇦
University Health Network, Toronto, Ontario, Canada

MR Guidance for Liver and Pancreas

Recruiting

Conditions: Magnetic Resonance Imaging

Interventions: Other: MRI

First Posted Date: 2018-07-10

Last Posted Date: 2024-06-18

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 30

Registration Number: NCT03582189

Locations: 🇨🇦
University Health Network - Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Achieving Value in Cancer Diagnostics: Blood Versus Tissue Molecular Profiling - a Prospective Canadian Study

Completed

Conditions: Non-small Cell Lung Cancer

Interventions: Diagnostic Test: GUARDANT360

First Posted Date: 2018-07-05

Last Posted Date: 2023-05-15

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 207

Registration Number: NCT03576937

Locations: 🇨🇦
BC Cancer Agency, Vancouver, British Columbia, Canada
🇨🇦
Tom Baker Cancer Centre, Calgary, Alberta, Canada
🇨🇦
Ottawa Hospital Regional Cancer Centre, Ottawa, Ontario, Canada

and more 3 locations

Sitravatinib (MGCD516) and Nivolumab in Oral Cavity Cancer Window Opportunity Study

Early Phase 1

Completed

Conditions: Squamous Cell Carcinoma, Head And Neck
Squamous Cell Carcinoma Mouth
Squamous Cell Carcinoma of the Oral Cavity

Interventions: Drug: Sitravatinib
Biological: Nivolumab

First Posted Date: 2018-07-02

Last Posted Date: 2023-07-27

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 10

Registration Number: NCT03575598

Locations: 🇨🇦
Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Canadian Network for Autoimmune Liver Disease

Recruiting

Conditions: Autoimmune Hepatitis
Overlap Syndrome
Primary Bilary Cirrhosis (PBC)

Interventions: Other: Observational; no intervention

First Posted Date: 2018-06-26

Last Posted Date: 2021-06-07

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 2500

Registration Number: NCT03569826

Locations: 🇨🇦
University of Alberta Hospital, Edmonton, Alberta, Canada
🇨🇦
St. Paul's Hospital, Vancouver, British Columbia, Canada
🇨🇦
Health Sciences Centre, Winnipeg, Manitoba, Canada

and more 11 locations

Lung Cancer Next Generation Sequencing Using the Oncomine Comprehensive Assay

Completed

Conditions: Lung Cancer Stage IV

Interventions: Diagnostic Test: Oncomine Comprehensive Assay

First Posted Date: 2018-06-15

Last Posted Date: 2022-05-17

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 134

Registration Number: NCT03558165

Locations: 🇨🇦
Princess Margaret Cancer Centre, Toronto, Ontario, Canada

A 3D Analysis of Mandibular Plating Strategies in Oromandibular Reconstruction.

Not Applicable

Completed

Conditions: Head and Neck Cancer

Interventions: Device: 3D mandibular plate

First Posted Date: 2018-06-08

Last Posted Date: 2020-12-16

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 20

Registration Number: NCT03550053

Locations: 🇨🇦
University Health Network, Toronto, Ontario, Canada

Hospital-wide Incidence, Clinical Characteristics and Outcomes of ARDS

Active, not recruiting

Conditions: Respiratory Failure
ARDS
Lung Ultrasound

First Posted Date: 2018-06-06

Last Posted Date: 2023-05-11

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 9999

Registration Number: NCT03546699

Locations: 🇮🇹
AOU Citta' della Salute e Della Scienza - Molinette, Torino, Italy
🇨🇦
University Health Network, Toronto, Ontario, Canada
🇮🇹
Ospedale San Giovanni Bosco, Torino, Italy

and more 1 locations

Effectiveness of the HF-ACP Website Study

Not Applicable

Conditions: Heart Failure
Advance Care Planning

Interventions: Behavioral: HF-ACP Website

First Posted Date: 2018-05-29

Last Posted Date: 2018-05-30

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 20

Registration Number: NCT03539510

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