University of Pennsylvania

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1740-11-14

Employees: 5K

Market Cap: -

Website: http://www.upenn.edu

Clinical Trials

Reverse Cholesterol Transport (RCT) Study

Not Applicable

Completed

Conditions: Healthy

Interventions: Other: 3H-Cholesterol

First Posted Date: 2009-12-15

Last Posted Date: 2018-12-20

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 18

Registration Number: NCT01031758

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Adaptive Treatment for Alcohol and Cocaine Dependence

Phase 2

Completed

Conditions: Substance Use Disorders

Interventions: Behavioral: Motivational Interviewing
Behavioral: Telephone counseling
Behavioral: Cognitive Behavioral Therapy (CBT) Counseling
Drug: medication management
Behavioral: Intensive OutPatient Therapy

First Posted Date: 2009-12-15

Last Posted Date: 2017-09-05

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 500

Registration Number: NCT01032135

Locations: 🇺🇸
Presbyterian Medical Center, Philadelphia, Pennsylvania, United States
🇺🇸
VAMC, Philadelphia, Pennsylvania, United States
🇺🇸
NorthEast Treatment Center, Philadelphia, Pennsylvania, United States

Patent Ductus Arteriosus (PDA) Screening Trial

Not Applicable

Completed

Conditions: Ductus Arteriosus, Patent

Interventions: Other: Nondisclosure of screening echocardiogram results
Other: Disclosure of screening echocardiogram results

First Posted Date: 2009-12-14

Last Posted Date: 2014-01-03

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 88

Registration Number: NCT01031316

Locations: 🇺🇸
Pennsylvania Hospital, Philadelphia, Pennsylvania, United States
🇺🇸
The Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

CART19 to Treat B-Cell Leukemia or Lymphoma That Are Resistant or Refractory to Chemotherapy

Phase 1

Completed

Conditions: Adult Acute Lymphoblastic Leukemia in Remission
Recurrent Grade 2 Follicular Lymphoma
Stage III Mantle Cell Lymphoma
Hematopoietic/Lymphoid Cancer
B-cell Chronic Lymphocytic Leukemia
Recurrent Adult Diffuse Large Cell Lymphoma
Recurrent Grade 3 Follicular Lymphoma
Recurrent Mantle Cell Lymphoma
Stage III Adult Diffuse Large Cell Lymphoma
Stage III Grade 1 Follicular Lymphoma

Interventions: Biological: CART-19

First Posted Date: 2009-12-10

Last Posted Date: 2023-06-22

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 26

Registration Number: NCT01029366

Locations: 🇺🇸
Abramson Cancer Center of The University of Pennsylvania, Philadelphia, Pennsylvania, United States

Desensitization With Belimumab in Sensitized Patients Awaiting Kidney Transplant

Phase 2

Terminated

Conditions: Desensitization

Interventions: Drug: Belimumab

First Posted Date: 2009-12-03

Last Posted Date: 2017-06-12

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 8

Registration Number: NCT01025193

Locations: 🇺🇸
University of Pennsyvlania Kidney Transplant Program, Philadelphia, Pennsylvania, United States

CD3/CD28 Bead Activated T-Cells Following Chemo-Immunotherapy in Patients With Chronic Lymphocytic Leukemia

Phase 1

Completed

Conditions: Chronic Lymphocytic Leukemia

Interventions: Biological: Infusion of CD3/CD28 stimulated T cells

First Posted Date: 2009-11-13

Last Posted Date: 2019-10-23

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 20

Registration Number: NCT01013441

Locations: 🇺🇸
Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, United States
🇺🇸
MD Anderson Cancer Center, University of Texas, Houston, Texas, United States

CD4-ZETA Gene Modified T Cells With and Without Exogenous Interleukin-2 (IL-2) In HIV Patients

Phase 1

Completed

Conditions: HIV-1 Infections

Interventions: Biological: T cells
Drug: HAART

First Posted Date: 2009-11-13

Last Posted Date: 2022-08-19

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 17

Registration Number: NCT01013415

Locations: 🇺🇸
Walter Reed Army Medical Center, Washington, District of Columbia, United States

Pilot Study of Text Message Reminders to Improve HIV Medication Adherence in Botswana

Not Applicable

Completed

Conditions: HIV Infections

First Posted Date: 2009-10-27

Last Posted Date: 2015-09-17

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 128

Registration Number: NCT01001741

Locations: 🇧🇼
Independence Surgery, Gaborone, Botswana

PGD2 Formation in Vascular Injury

Terminated

Conditions: Stable Angina
Acute Coronary Syndrome
Coronary Artery Disease

Interventions: Drug: No ASA
Drug: 325 mg ASA
Drug: Low dose ASA

First Posted Date: 2009-10-26

Last Posted Date: 2019-06-11

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 51

Registration Number: NCT01001260

Neural Substrates in Nicotine Withdrawal

Phase 2

Completed

Conditions: Tobacco Use Disorder

Interventions: Drug: Placebo
Drug: Tolcapone

First Posted Date: 2009-10-26

Last Posted Date: 2014-07-02

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 218

Registration Number: NCT01001520

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

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