University of Pennsylvania

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1740-11-14

Employees: 5K

Market Cap: -

Website: http://www.upenn.edu

Clinical Trials

NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)

Phase 1

Terminated

Conditions: Myxoid/Round Cell Liposarcoma
Multiple Myeloma
Melanoma
Synovial Sarcoma

Interventions: Biological: NY-ESO-1 redirected autologous T cells with CRISPR edited endogenous TCR and PD-1
Drug: Cyclophosphamide
Drug: Fludarabine
Device: NY-ESO-1 expression testing

First Posted Date: 2018-01-16

Last Posted Date: 2023-06-22

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 3

Registration Number: NCT03399448

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Effect of Galantamine on Inflammation and Cognition

Phase 2

Completed

Conditions: HIV Associated Cognitive Motor Complex

Interventions: Drug: Galantamine
Drug: Placebo

First Posted Date: 2017-12-27

Last Posted Date: 2024-10-17

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 63

Registration Number: NCT03384784

Locations: 🇺🇸
Center for Interdisciplinary Research on Nicotine Addiction, University of Pennsylvania, Philadelphia, Pennsylvania, United States

Psoriatic Arthritis Research Collaborative: Biologic Sub-Study

Completed

Conditions: Psoriatic Arthritis

First Posted Date: 2017-12-19

Last Posted Date: 2024-02-07

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 20

Registration Number: NCT03378336

Locations: 🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
🇺🇸
Hospital at the University of Pennsylvania, Philadelphia, Pennsylvania, United States
🇺🇸
University of Utah, Salt Lake City, Utah, United States

and more 1 locations

Administration of Zepatier (Grazoprevir Plus Elbasvir) in Chronic Hemodialysis (HD) Patients With Hepatitis C

Phase 4

Completed

Conditions: Hepatitis C
Hemodialysis
Nosocomial Infection

Interventions: Drug: Elbasvir 50 MG / Grazoprevir 100 MG [Zepatier]

First Posted Date: 2017-12-07

Last Posted Date: 2021-12-15

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 6

Registration Number: NCT03365635

Locations: 🇺🇸
Penn Presbyterian Medical Center, Philadelphia, Pennsylvania, United States

Hypoglossal Nerve Stimulation on Cardiovascular Outcomes

Not Applicable

Completed

Conditions: Obstructive Sleep Apnea

Interventions: Device: Therapeutic HGNS
Device: Subtherapeutic 'Sham' HGNS

First Posted Date: 2017-12-02

Last Posted Date: 2023-03-30

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 63

Registration Number: NCT03359096

Locations: 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Daytime vs. Delayed Eating Among Obese Individuals

Not Applicable

Completed

Conditions: Obesity

Interventions: Behavioral: Eating Condition

First Posted Date: 2017-11-27

Last Posted Date: 2023-10-18

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 30

Registration Number: NCT03354169

Locations: 🇺🇸
Center for Weight and Eating Disorders, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States

Reality Check: An HIV Risk Reduction Serial Drama

Not Applicable

Completed

Conditions: Sexually Transmitted Diseases
HIV (Human Immunodeficiency Virus)

Interventions: Behavioral: Reality Check
Behavioral: Physical Activity Attention Control

First Posted Date: 2017-11-24

Last Posted Date: 2017-11-24

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 203

Registration Number: NCT03352219

Locations: 🇺🇸
Annenberg School for Communication, University of Pennsylvania, Philadelphia, Pennsylvania, United States

Impact of Transjugular Intrahepatic Portosystemic Shunts on Liver Stiffness

Not Applicable

Terminated

Conditions: Liver Fibroses
Portal Hypertension

Interventions: Diagnostic Test: Ultrasound

First Posted Date: 2017-11-24

Last Posted Date: 2019-10-01

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 1

Registration Number: NCT03352882

Locations: 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

HIV/STI Prevention Among Black Adolescents With Mental Illnesses (Project GOLD)

Not Applicable

Completed

Conditions: Emotional Disturbances
STI
Mental Disorder
HIV

Interventions: Behavioral: General Health Control Intervention
Behavioral: HIV/STI Prevention Intervention

First Posted Date: 2017-11-21

Last Posted Date: 2017-11-29

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 108

Registration Number: NCT03348813

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Study of Immune Responses to Influenza Vaccination

Phase 4

Recruiting

Conditions: Influenza Vaccination

Interventions: Biological: Influenza vaccination

First Posted Date: 2017-11-17

Last Posted Date: 2024-08-28

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 75

Registration Number: NCT03346772

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

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