University of Pennsylvania

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1740-11-14

Employees: 5K

Market Cap: -

Website: http://www.upenn.edu

Clinical Trials

Journey of Patients With Vasculitis From First Symptom to Diagnosis

Completed

Conditions: Vasculitis
Systemic Vasculitis
Cryoglobulinemic Vasculitis
Temporal Arteritis
Giant Cell Arteritis
IgA Vasculitis
CNS Vasculitis
Eosinophilic Granulomatous Vasculitis
Wegener Granulomatosis
Henoch Schonlein Purpura

Interventions: Other: Online Questionnaire

First Posted Date: 2018-01-25

Last Posted Date: 2018-06-06

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 456

Registration Number: NCT03410290

Locations: 🇺🇸
University of South Florida, Tampa, Florida, United States

Air Pollution, Asthma and Circadian Clocks

Active, not recruiting

Conditions: Asthma
Healthy

Interventions: Other: Observational

First Posted Date: 2018-01-23

Last Posted Date: 2025-01-20

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 20

Registration Number: NCT03406351

Locations: 🇺🇸
University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States

Niraparib + Ipilimumab or Nivolumab in Progression Free Pancreatic Adenocarcinoma After Platinum-Based Chemotherapy

Phase 1

Completed

Conditions: Pancreatic Adenocarcinoma

Interventions: Drug: Niraparib + Ipilimumab
Drug: Niraparib + Nivolumab

First Posted Date: 2018-01-19

Last Posted Date: 2025-05-14

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 104

Registration Number: NCT03404960

Locations: 🇺🇸
University of Pennsylvania, Abramson Cancer Center, Philadelphia, Pennsylvania, United States

NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)

Phase 1

Terminated

Conditions: Myxoid/Round Cell Liposarcoma
Multiple Myeloma
Melanoma
Synovial Sarcoma

Interventions: Biological: NY-ESO-1 redirected autologous T cells with CRISPR edited endogenous TCR and PD-1
Drug: Cyclophosphamide
Drug: Fludarabine
Device: NY-ESO-1 expression testing

First Posted Date: 2018-01-16

Last Posted Date: 2023-06-22

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 3

Registration Number: NCT03399448

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Effect of Galantamine on Inflammation and Cognition

Phase 2

Completed

Conditions: HIV Associated Cognitive Motor Complex

Interventions: Drug: Galantamine
Drug: Placebo

First Posted Date: 2017-12-27

Last Posted Date: 2024-10-17

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 63

Registration Number: NCT03384784

Locations: 🇺🇸
Center for Interdisciplinary Research on Nicotine Addiction, University of Pennsylvania, Philadelphia, Pennsylvania, United States

Psoriatic Arthritis Research Collaborative: Biologic Sub-Study

Completed

Conditions: Psoriatic Arthritis

First Posted Date: 2017-12-19

Last Posted Date: 2025-05-09

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 171

Registration Number: NCT03378336

Locations: 🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
🇺🇸
Hospital at the University of Pennsylvania, Philadelphia, Pennsylvania, United States
🇺🇸
University of Utah, Salt Lake City, Utah, United States

and more 1 locations

Administration of Zepatier (Grazoprevir Plus Elbasvir) in Chronic Hemodialysis (HD) Patients With Hepatitis C

Phase 4

Completed

Conditions: Hepatitis C
Hemodialysis
Nosocomial Infection

Interventions: Drug: Elbasvir 50 MG / Grazoprevir 100 MG [Zepatier]

First Posted Date: 2017-12-07

Last Posted Date: 2021-12-15

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 6

Registration Number: NCT03365635

Locations: 🇺🇸
Penn Presbyterian Medical Center, Philadelphia, Pennsylvania, United States

Hypoglossal Nerve Stimulation on Cardiovascular Outcomes

Not Applicable

Completed

Conditions: Obstructive Sleep Apnea

Interventions: Device: Therapeutic HGNS
Device: Subtherapeutic 'Sham' HGNS

First Posted Date: 2017-12-02

Last Posted Date: 2023-03-30

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 63

Registration Number: NCT03359096

Locations: 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Daytime vs. Delayed Eating Among Obese Individuals

Not Applicable

Completed

Conditions: Obesity

Interventions: Behavioral: Eating Condition

First Posted Date: 2017-11-27

Last Posted Date: 2023-10-18

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 30

Registration Number: NCT03354169

Locations: 🇺🇸
Center for Weight and Eating Disorders, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States

Impact of Transjugular Intrahepatic Portosystemic Shunts on Liver Stiffness

Not Applicable

Terminated

Conditions: Liver Fibroses
Portal Hypertension

Interventions: Diagnostic Test: Ultrasound

First Posted Date: 2017-11-24

Last Posted Date: 2019-10-01

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 1

Registration Number: NCT03352882

Locations: 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

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