CHILDREN'S HOSPITAL LOS ANGELES

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1901-04-01

Employees: 5K

Market Cap: -

Website: http://www.chla.org

Clinical Trials

Changes in Pituitary Iron and Volume With Deferasirox

Completed

Conditions: Iron Overload

First Posted Date: 2011-06-20

Last Posted Date: 2023-10-31

Lead Sponsor: Children's Hospital Los Angeles

Target Recruit Count: 130

Registration Number: NCT01376622

Locations: 🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States

Nutrition and Body Composition in Acute Lymphoblastic Leukemia

Phase 2

Completed

Conditions: Precursor Cell Lymphoblastic Leukemia-Lymphoma
Vitamin D Deficiency

Interventions: Dietary Supplement: Vitamin D and Calcium Citrate

First Posted Date: 2011-03-18

Last Posted Date: 2020-07-08

Lead Sponsor: Children's Hospital Los Angeles

Target Recruit Count: 76

Registration Number: NCT01317940

Locations: 🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States

Iron Mediated Vascular Disease in Sickle Cell Anemia Patients

Completed

Conditions: Sickle Cell Disease

First Posted Date: 2010-11-15

Last Posted Date: 2019-01-10

Lead Sponsor: Children's Hospital Los Angeles

Target Recruit Count: 150

Registration Number: NCT01239901

Locations: 🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States

Omegaven Treatment of Parenteral Nutrition (PN) Induced Liver Injury

Not Applicable

Completed

Conditions: Liver Injury

Interventions: Other: Historical Controls
Drug: Omegaven™

First Posted Date: 2010-03-18

Last Posted Date: 2019-05-06

Lead Sponsor: Children's Hospital Los Angeles

Target Recruit Count: 90

Registration Number: NCT01089426

Locations: 🇺🇸
Childrens Hospital Los Angeles, Los Angeles, California, United States

Safety and Efficacy of Sodium Nitrite in Sickle Cell Disease

Phase 1

Terminated

Conditions: Sickle Cell Disease

Interventions: Drug: sodium nitrite injection, usp

First Posted Date: 2009-12-16

Last Posted Date: 2017-10-17

Lead Sponsor: Children's Hospital Los Angeles

Target Recruit Count: 5

Registration Number: NCT01033227

Locations: 🇺🇸
Childrens Hospital Los Angeles, Los Angeles, California, United States

A Study of Vincristine, Escalating Doses of Irinotecan, Temozolomide and Bevacizumab (Vit-b) in Pediatric and Adolescent Patients With Recurrent or Refractory Solid Tumors of Non-hematopoietic Origin

Phase 1

Completed

Conditions: Refractory Solid Tumors in Children

Interventions: Drug: Irinotecan
Drug: Vincristine
Drug: Temozolomide
Drug: Bevacizumab

First Posted Date: 2009-10-09

Last Posted Date: 2023-10-06

Lead Sponsor: Children's Hospital Los Angeles

Target Recruit Count: 13

Registration Number: NCT00993044

Locations: 🇺🇸
Childrens Hospital los Angeles, Los Angeles, California, United States

Clinical Importance of Treating Iron Overload in Sickle Cell Disease

Phase 3

Terminated

Conditions: Anemia, Sickle Cell
Transfusion Hemosiderosis

Interventions: Drug: deferasirox

First Posted Date: 2009-09-22

Last Posted Date: 2017-02-08

Lead Sponsor: Children's Hospital Los Angeles

Target Recruit Count: 1

Registration Number: NCT00981370

Locations: 🇺🇸
Childrens Hospital Los Angeles, Los Angeles, California, United States

Use of Pan-vascular Endothelial Growth Factor Receptor (Pan-VEGF) Blockade for the Treatment of Retinopathy of Prematurity (ROP) (Compassionate Use BLOCK-ROP)

Conditions: Retinopathy of Prematurity

First Posted Date: 2009-03-27

Last Posted Date: 2023-11-24

Lead Sponsor: Children's Hospital Los Angeles

Registration Number: NCT00870636

Locations: 🇺🇸
Childrens Hospital Los Angeles, Los Angeles, California, United States

Study to Evaluate Impact of School-based Influenza Vaccination on School Populations

Not Applicable

Completed

Conditions: Influenza

Interventions: Biological: School-based influenza vaccination program

First Posted Date: 2009-02-13

Last Posted Date: 2016-09-12

Lead Sponsor: Children's Hospital Los Angeles

Target Recruit Count: 4455

Registration Number: NCT00844051

Locations: 🇺🇸
Los Angeles County Department of Public Health, Los Angeles, California, United States
🇺🇸
Childrens Hospital Los Angeles, Los Angeles, California, United States

Activity and Content of Factor VIII (FVIII) in Human Plasma: The Assessment of a Novel Immunoassay

Not Applicable

Completed

Conditions: Hemophilia A

Interventions: Other: FVIII immuno-assay

First Posted Date: 2009-02-09

Last Posted Date: 2017-02-01

Lead Sponsor: Children's Hospital Los Angeles

Target Recruit Count: 7

Registration Number: NCT00839202

Locations: 🇺🇸
Department of Biochemistry University of Vermont, Burlington, Vermont, United States

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