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NATIONAL INSTITUTES OF HEALTH

🇺🇸United States

Country: 🇺🇸United States

Ownership: Subsidiary, Private

Established: 1948-01-01

Employees: 1K

Market Cap: -

Website: http://www.nidcr.nih.gov

Clinical Trials

Montelukast to Treat Bronchiolitis Obliterans

Phase 2

Completed

Conditions: Bronchiolitis Obliterans
Chronic Graft Versus Host Disease
Leukotriene
Montelukast
Stem Cell Transplant

Interventions: Drug: Singulair (Montelukast Sodium)

First Posted Date: 2008-04-10

Last Posted Date: 2018-04-09

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 25

Registration Number: NCT00656058

Locations: 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma

Phase 1

Completed

Conditions: Adult Anaplastic Astrocytoma
Adult Anaplastic Oligodendroglioma
Adult Giant Cell Glioblastoma
Adult Glioblastoma
Adult Gliosarcoma
Adult Mixed Glioma
Recurrent Adult Brain Tumor

Interventions: Drug: ziv-aflibercept
Procedure: radiation therapy
Drug: temozolomide
Procedure: pharmacological study
Procedure: laboratory biomarker analysis

First Posted Date: 2008-04-02

Last Posted Date: 2014-05-30

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 61

Registration Number: NCT00650923

Locations: 🇺🇸
University of California at Los Angeles (UCLA ), Los Angeles, California, United States
🇺🇸
UCSF-Mount Zion, San Francisco, California, United States
🇺🇸
University of California San Francisco Medical Center-Parnassus, San Francisco, California, United States

and more 6 locations

Viral Therapy in Treating Patients With Metastatic Melanoma

Phase 2

Completed

Conditions: Stage IV Melanoma
Recurrent Melanoma

Interventions: Biological: wild-type reovirus

First Posted Date: 2008-04-02

Last Posted Date: 2014-04-22

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 23

Registration Number: NCT00651157

Locations: 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States

Effect of Physical Activity on Metabolic Syndrome in Pregnancy & Fetal Outcome

Phase 3

Completed

Conditions: Obesity
Pregnancy
Diabetes Mellitus

Interventions: Behavioral: Experimental group

First Posted Date: 2008-03-31

Last Posted Date: 2015-04-22

Lead Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Target Recruit Count: 100

Registration Number: NCT00647595

Locations: 🇺🇸
Madigan Army Medical Center, Ft Lewis, Washington, United States

Inflammatory Breast Cancer, Tumor Markers, and Factors Associated With Angiogenesis

Completed

Conditions: Breast Neoplasms

First Posted Date: 2008-03-28

Last Posted Date: 2017-07-02

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 300

Registration Number: NCT00646555

Locations: 🇺🇸
GW University Medical Center GW Hospital Center, Washington, D.C., District of Columbia, United States

Natural History of Familial Carcinoid Tumor

Recruiting

Conditions: Carcinoid

Interventions: Drug: [18F]-DOPA

First Posted Date: 2008-03-28

Last Posted Date: 2025-07-01

Lead Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Target Recruit Count: 1600

Registration Number: NCT00646022

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Lenalidomide and Dexamethasone With or Without Bortezomib in Treating Patients With Previously Untreated Multiple Myeloma

Phase 3

Active, not recruiting

Conditions: DS Stage III Multiple Myeloma
DS Stage I Multiple Myeloma
DS Stage II Multiple Myeloma

Interventions: Drug: Dexamethasone
Drug: Bortezomib
Other: Laboratory Biomarker Analysis
Drug: Lenalidomide

First Posted Date: 2008-03-26

Last Posted Date: 2025-05-11

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 525

Registration Number: NCT00644228

Locations: 🇺🇸
Providence Alaska Medical Center, Anchorage, Alaska, United States
🇺🇸
Mayo Clinic in Arizona, Scottsdale, Arizona, United States
🇺🇸
University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona, United States

and more 496 locations

SNX-5422 to Treat Solid Tumor Cancers and Lymphomas

Phase 1

Completed

Conditions: Lymphoma
Neoplasms

First Posted Date: 2008-03-26

Last Posted Date: 2017-07-02

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 33

Registration Number: NCT00644072

Locations: 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Vorinostat and Bortezomib in Treating Patients With Progressive, Recurrent Glioblastoma Multiforme

Phase 2

Completed

Conditions: Adult Giant Cell Glioblastoma
Adult Glioblastoma
Adult Gliosarcoma
Recurrent Adult Brain Tumor

Interventions: Drug: vorinostat
Procedure: therapeutic conventional surgery
Drug: bortezomib

First Posted Date: 2008-03-24

Last Posted Date: 2014-05-14

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 44

Registration Number: NCT00641706

Locations: 🇺🇸
Mayo Clinic in Arizona, Scottsdale, Arizona, United States
🇺🇸
The Medical Center of Aurora, Aurora, Colorado, United States
🇺🇸
Boulder Community Hospital, Boulder, Colorado, United States

and more 210 locations

Curcumin in Treating Patients With Familial Adenomatous Polyposis

Phase 2

Completed

Conditions: Familial Adenomatous Polyposis

Interventions: Other: Laboratory Biomarker Analysis
Drug: Curcumin
Other: Placebo

First Posted Date: 2008-03-24

Last Posted Date: 2017-09-29

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 44

Registration Number: NCT00641147

Locations: 🇺🇸
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland, United States
🇵🇷
University of Puerto Rico, San Juan, Puerto Rico

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