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NATIONAL INSTITUTES OF HEALTH

NATIONAL INSTITUTES OF HEALTH logo
πŸ‡ΊπŸ‡ΈUnited States
Ownership
Subsidiary, Private
Established
1948-01-01
Employees
1K
Market Cap
-
Website
http://www.nidcr.nih.gov

Dasatinib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia That Did Not Respond to Imatinib Mesylate

Phase 1
Completed
Conditions
Accelerated Phase Chronic Myelogenous Leukemia
Blastic Phase Chronic Myelogenous Leukemia
Childhood Chronic Myelogenous Leukemia
Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Meningeal Chronic Myelogenous Leukemia
Recurrent Childhood Acute Lymphoblastic Leukemia
Relapsing Chronic Myelogenous Leukemia
Unspecified Childhood Solid Tumor, Protocol Specific
Interventions
Other: pharmacological study
Other: laboratory biomarker analysis
First Posted Date
2006-04-21
Last Posted Date
2013-02-05
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
48
Registration Number
NCT00316953
Locations
πŸ‡ΊπŸ‡Έ

Children's Oncology Group, Arcadia, California, United States

Stem Cell Collection

Terminated
Conditions
Stem Cells
First Posted Date
2006-04-19
Last Posted Date
2019-12-17
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Target Recruit Count
429
Registration Number
NCT00316069
Locations
πŸ‡ΊπŸ‡Έ

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Azacitidine With or Without Entinostat in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia

Phase 2
Completed
Conditions
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
Adult Acute Myeloid Leukemia in Remission
Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11
Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11
Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1
Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL
Adult Acute Promyelocytic Leukemia With t(15;17)(q22;q12); PML-RARA
Alkylating Agent-Related Acute Myeloid Leukemia
Recurrent Adult Acute Myeloid Leukemia
Chronic Myelomonocytic Leukemia
Interventions
Other: Laboratory Biomarker Analysis
First Posted Date
2006-04-12
Last Posted Date
2017-02-02
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
197
Registration Number
NCT00313586
Locations
πŸ‡ΊπŸ‡Έ

Clements University Hospital, Dallas, Texas, United States

πŸ‡ΊπŸ‡Έ

Union Hospital of Cecil County, Elkton, Maryland, United States

πŸ‡ΊπŸ‡Έ

Hematology and Oncology Associates, Chicago, Illinois, United States

and more 231 locations

Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1

Completed
Conditions
Neurofibromatosis Type 1
Neurofibroma
First Posted Date
2006-04-12
Last Posted Date
2025-06-15
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
17
Registration Number
NCT00314119
Locations
πŸ‡ΊπŸ‡Έ

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Oxaliplatin and Topotecan in Advance Ovarian Cancer

Phase 2
Terminated
Conditions
Recurrent Ovarian Epithelial Cancer
Interventions
First Posted Date
2006-04-12
Last Posted Date
2015-11-27
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
39
Registration Number
NCT00313612
Locations
πŸ‡ΊπŸ‡Έ

NYU Cancer Institute, New York, New York, United States

πŸ‡ΊπŸ‡Έ

Montefiore Medical Center, Bronx, New York, United States

Chemotherapy, Irradiation, Cell Infusions, and Interleukin-2 to Treat Metastatic Melanoma

Phase 2
Completed
Conditions
Metastatic Melanoma
Interventions
Biological: Melanoma Reactive TIL
Biological: IL-2
Radiation: 1200 total body irradiation (TBI)
First Posted Date
2006-04-12
Last Posted Date
2012-10-18
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
26
Registration Number
NCT00314106
Locations
πŸ‡ΊπŸ‡Έ

National Cancer Institute (NCI), Bethesda, Maryland, United States

Thyroid and Fat Tissue Metabolism

Completed
Conditions
Healthy Volunteers
First Posted Date
2006-04-10
Last Posted Date
2017-10-06
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Target Recruit Count
41
Registration Number
NCT00312715
Locations
πŸ‡ΊπŸ‡Έ

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Phase 3
Active, not recruiting
Conditions
Breast Adenocarcinoma
Stage IA Breast Cancer AJCC v7
Stage IB Breast Cancer AJCC v7
Stage IIA Breast Cancer AJCC v6 and v7
Stage IIB Breast Cancer AJCC v6 and v7
Stage IIIB Breast Cancer AJCC v7
Hormone Receptor Positive
Interventions
Other: Laboratory Biomarker Analysis
Other: Quality-of-Life Assessment
Radiation: Radiation Therapy
First Posted Date
2006-04-03
Last Posted Date
2025-06-24
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
10273
Registration Number
NCT00310180
Locations
πŸ‡΅πŸ‡·

San Juan City Hospital, San Juan, Puerto Rico

πŸ‡ΊπŸ‡Έ

Kaiser Permanente-Franklin, Denver, Colorado, United States

πŸ‡ΊπŸ‡Έ

Northeast Alabama Regional Medical Center, Anniston, Alabama, United States

and more 1212 locations

AZD2171 and Combination Chemotherapy in Treating Women With Locally Advanced Breast Cancer

Not Applicable
Completed
Conditions
Breast Cancer
First Posted Date
2006-04-03
Last Posted Date
2013-06-20
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
33
Registration Number
NCT00310089
Locations
πŸ‡ΊπŸ‡Έ

Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support, Bethesda, Maryland, United States

πŸ‡ΊπŸ‡Έ

Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States

Vorinostat and Bortezomib in Treating Patients With Relapsed or Refractory Multiple Myeloma

Phase 1
Completed
Conditions
Refractory Multiple Myeloma
Stage I Multiple Myeloma
Stage II Multiple Myeloma
Stage III Multiple Myeloma
Interventions
Other: laboratory biomarker analysis
Other: pharmacological study
First Posted Date
2006-04-03
Last Posted Date
2013-02-07
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
40
Registration Number
NCT00310024
Locations
πŸ‡ΊπŸ‡Έ

University of Maryland Greenebaum Cancer Center, Baltimore, Maryland, United States

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