MedPath

NATIONAL INSTITUTES OF HEALTH

NATIONAL INSTITUTES OF HEALTH logo
🇺🇸United States
Ownership
Subsidiary, Private
Established
1948-01-01
Employees
1K
Market Cap
-
Website
http://www.nidcr.nih.gov

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

Phase 3
Active, not recruiting
Conditions
Anal Basaloid Carcinoma
Anal Canal Cloacogenic Carcinoma
Metastatic Anal Squamous Cell Carcinoma
Recurrent Anal Squamous Cell Carcinoma
Stage III Anal Cancer AJCC v8
Stage IV Anal Cancer AJCC v8
Unresectable Anal Squamous Cell Carcinoma
Interventions
First Posted Date
2020-06-24
Last Posted Date
2025-03-26
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
205
Registration Number
NCT04444921
Locations
🇺🇸

Walter Knox Memorial Hospital, Emmett, Idaho, United States

🇺🇸

Anchorage Associates in Radiation Medicine, Anchorage, Alaska, United States

🇺🇸

Anchorage Radiation Therapy Center, Anchorage, Alaska, United States

and more 579 locations

Machine Learning to Analyze Facial Imaging, Voice and Spoken Language for the Capture and Classification of Cancer/Tumor Pain

Completed
Conditions
Solid Tumors
Neoplasms
Cancer
First Posted Date
2020-06-22
Last Posted Date
2025-05-28
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
83
Registration Number
NCT04442425
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Testing Palbociclib (PD-0332991) as a Potential Targeted Treatment in Cancers With CCND1, 2, 3 Amplification (MATCH-Subprotocol Z1B)

Phase 2
Active, not recruiting
Conditions
Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Hematopoietic and Lymphoid Cell Neoplasm
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Interventions
First Posted Date
2020-06-19
Last Posted Date
2025-01-07
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
40
Registration Number
NCT04439201
Locations
🇺🇸

ECOG-ACRIN Cancer Research Group, Philadelphia, Pennsylvania, United States

Testing GDC-0032 (Taselisib) as a Potential Targeted Treatment in Cancers With PIK3CA Genetic Changes (MATCH-Subprotocol I)

Phase 2
Active, not recruiting
Conditions
Advanced Malignant Solid Neoplasm
Hematopoietic and Lymphoid Cell Neoplasm
Advanced Lymphoma
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma
Interventions
First Posted Date
2020-06-19
Last Posted Date
2025-05-07
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
70
Registration Number
NCT04439175
Locations
🇺🇸

ECOG-ACRIN Cancer Research Group, Philadelphia, Pennsylvania, United States

Testing Nivolumab as a Potential Targeted Treatment in Cancers With Mismatch Repair Deficiency (MATCH-Subprotocol Z1D)

Phase 2
Completed
Conditions
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Plasma Cell Myeloma
Advanced Lymphoma
Hematopoietic and Lymphoid Cell Neoplasm
Advanced Malignant Solid Neoplasm
Interventions
Biological: Nivolumab
First Posted Date
2020-06-19
Last Posted Date
2021-04-06
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
47
Registration Number
NCT04439214
Locations
🇺🇸

ECOG-ACRIN Cancer Research Group, Philadelphia, Pennsylvania, United States

Testing Trametinib as a Potential Targeted Treatment in Cancers With BRAF Genetic Changes (MATCH-Subprotocol R)

Phase 2
Active, not recruiting
Conditions
Advanced Malignant Solid Neoplasm
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma
Advanced Lymphoma
Hematopoietic and Lymphoid Cell Neoplasm
Refractory Lymphoma
Interventions
First Posted Date
2020-06-19
Last Posted Date
2025-05-07
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
35
Registration Number
NCT04439279
Locations
🇺🇸

ECOG-ACRIN Cancer Research Group, Philadelphia, Pennsylvania, United States

Testing Afatinib as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol B)

Phase 2
Active, not recruiting
Conditions
Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Hematopoietic and Lymphoid Cell Neoplasm
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma
Interventions
First Posted Date
2020-06-19
Last Posted Date
2025-03-28
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
40
Registration Number
NCT04439136
Locations
🇺🇸

ECOG-ACRIN Cancer Research Group, Philadelphia, Pennsylvania, United States

Testing Crizotinib as a Potential Targeted Treatment in Cancers With ALK Genetic Changes (MATCH-Subprotocol F)

Phase 2
Active, not recruiting
Conditions
Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Hematopoietic and Lymphoid Cell Neoplasm
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma
Interventions
First Posted Date
2020-06-19
Last Posted Date
2025-05-07
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
5
Registration Number
NCT04439266
Locations
🇺🇸

ECOG-ACRIN Cancer Research Group, Philadelphia, Pennsylvania, United States

Testing Trametinib as a Potential Targeted Treatment in Cancers With GNAQ or GNA11 Genetic Changes (MATCH-Subprotocol S2)

Phase 2
Active, not recruiting
Conditions
Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Hematopoietic and Lymphoid Cell Neoplasm
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma
Interventions
First Posted Date
2020-06-19
Last Posted Date
2025-03-14
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
4
Registration Number
NCT04439357
Locations
🇺🇸

ECOG-ACRIN Cancer Research Group, Philadelphia, Pennsylvania, United States

Testing AZD1775 as a Potential Targeted Treatment in Cancers With BRCA Genetic Changes (MATCH-Subprotocol Z1I)

Phase 2
Active, not recruiting
Conditions
Advanced Lymphoma
Hematopoietic and Lymphoid Cell Neoplasm
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma
Advanced Malignant Solid Neoplasm
Interventions
First Posted Date
2020-06-19
Last Posted Date
2025-05-01
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
35
Registration Number
NCT04439227
Locations
🇺🇸

ECOG-ACRIN Cancer Research Group, Philadelphia, Pennsylvania, United States

© Copyright 2025. All Rights Reserved by MedPath