KHON KAEN UNIVERSITY

Urinary Cyclophilin A Identified as Early Marker for Chronic Kidney Disease in Type 2 Diabetes

8 months ago

• Researchers have identified urinary cyclophilin A (uCypA) as a potential early biomarker for chronic kidney disease (CKD) in patients with type 2 diabetes (T2DM). • The study demonstrated that uCypA levels are significantly elevated in T2DM patients with early-stage CKD compared to those without CKD. • A lateral flow strip (LFS) assay was developed for rapid detection of uCypA, offering a point-of-care diagnostic tool. • These findings suggest that uCypA could facilitate earlier diagnosis and intervention for CKD in individuals with T2DM.