Avidity Biosciences
- Country
- 🇺🇸United States
- Ownership
- Public
- Established
- 2013-01-01
- Employees
- 253
- Market Cap
- $5.1B
- Introduction
Avidity Biosciences, Inc. engages in the development of a new class of oligonucleotide-based therapies called Antibody Oligonucleotide Conjugates (AOC). It utilizes its AOC platform to design, engineer, and develop therapeutics that combine the tissue selectivity of monoclonal antibodies and the precision of oligonucleotide-based therapies in order to access previously undruggable tissue and cell types and more effectively target underlying genetic drivers of diseases. The company was founded by Troy E. Wilson, Kent Hawryluk, Mark E. Davis, and Francis Patrick McCormick on November 13, 2012 and is headquartered in San Diego, CA.
Clinical Trials
10
Trial Phases
3 Phases
Drug Approvals
0
Drug Approvals
No drug approvals found
This company may not have drug approvals in our database
Clinical Trials
Distribution across different clinical trial phases (9 trials with phase data)• Click on a phase to view related trials
A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD
- Conditions
- Facioscapulohumeral Muscular DystrophyFSHDFSHD - Facioscapulohumeral Muscular DystrophyFSHD1FSHD2Fascioscapulohumeral Muscular DystrophyFascioscapulohumeral Muscular Dystrophy Type 1Fascioscapulohumeral Muscular Dystrophy Type 2Facioscapulohumeral Muscular Dystrophy 1Facioscapulohumeral Dystrophy
- Interventions
- Drug: Placebo
- First Posted Date
- 2025-06-26
- Last Posted Date
- 2025-06-26
- Lead Sponsor
- Avidity Biosciences, Inc.
- Target Recruit Count
- 200
- Registration Number
- NCT07038200
- Locations
- 🇺🇸
University of California Irvine, Orange, California, United States
🇺🇸Stanford University, Palo Alto, California, United States
🇺🇸University of Colorado, Denver, Colorado, United States
Global Open-Label Extension Study of Del-desiran for the Treatment of DM1
- Conditions
- Myotonic Dystrophy Type 1DM1MyotoniaMyotonic Dystrophy 1Myotonic DystrophyMyotonic DisordersSteinert Myotonic DystrophySteinert's Disease
- Interventions
- Drug: Del-desiran (AOC 1001)
- First Posted Date
- 2025-06-06
- Last Posted Date
- 2025-06-06
- Lead Sponsor
- Avidity Biosciences, Inc.
- Target Recruit Count
- 217
- Registration Number
- NCT07008469
Phase 2 Open-label Extension Study of AOC 1020 in Participants with Facioscapulohumeral Muscular Dystrophy (FSHD)
- Conditions
- FSHDFSHD1FSHD2FMDFMD2Fascioscapulohumeral Muscular DystrophyFascioscapulohumeral Muscular Dystrophy Type 1Fascioscapulohumeral Muscular Dystrophy Type 2Dystrophies, Facioscapulohumeral MuscularDystrophy, Facioscapulohumeral Muscular
- Interventions
- First Posted Date
- 2024-08-09
- Last Posted Date
- 2024-12-20
- Lead Sponsor
- Avidity Biosciences, Inc.
- Target Recruit Count
- 84
- Registration Number
- NCT06547216
- Locations
- 🇺🇸
University of California Los Angeles, Los Angeles, California, United States
🇺🇸Stanford University, Palo Alto, California, United States
🇺🇸University of California San Diego, San Diego, California, United States
Global Study of Del-desiran for the Treatment of DM1
- Conditions
- Myotonic Dystrophy 1Myotonic DisordersDM1Myotonic DystrophySteinertDystrophy MyotonicSteinert DiseaseMyotonic Muscular DystrophyMyotoniaMyotonic Dystrophy Type 1 (DM1)
- Interventions
- Drug: AOC 1001 (del-desiran)Drug: Placebo
- First Posted Date
- 2024-05-13
- Last Posted Date
- 2025-05-25
- Lead Sponsor
- Avidity Biosciences, Inc.
- Target Recruit Count
- 150
- Registration Number
- NCT06411288
- Locations
- 🇺🇸
Stanford University, Stanford, California, United States
🇺🇸University of Colorado, Denver, Colorado, United States
🇺🇸University of Florida, Gainesville, Florida, United States
Ph2 Open-label Study of AOC 1044 in Duchenne Muscular Dystrophy Participants With Mutations Amenable to Exon44 Skipping
- Conditions
- DMDDuchenne Muscular DystrophyDuchenneExon 44
- Interventions
- First Posted Date
- 2024-02-06
- Last Posted Date
- 2025-05-14
- Lead Sponsor
- Avidity Biosciences, Inc.
- Target Recruit Count
- 39
- Registration Number
- NCT06244082
- Locations
- 🇺🇸
Arkansas Children's Hospital, Little Rock, Arkansas, United States
🇺🇸University of California, San Diego, Rady's Children's Hospital, La Jolla, California, United States
🇺🇸UC Davis Medical Center, Sacramento, California, United States
- Prev
- 1
- 2
- Next
News
CRISPR Screen Reveals Key to Enhancing RNA Drug Efficacy Through Endosomal Transport Modulation
Researchers at University of Basel and Roche used CRISPR/Cas9 screening to identify genes that significantly influence antisense oligonucleotide (ASO) activity, revealing that intracellular transport speed is a critical determinant of therapeutic efficacy.
Applied DNA Sciences Restructures Operations to Focus on Synthetic DNA Manufacturing for Gene Therapies
Applied DNA Sciences implemented a 27% workforce reduction and ceased operations at Applied DNA Clinical Labs to focus exclusively on its synthetic DNA manufacturing subsidiary LineaRx.
Sensible Biotechnologies Achieves 90% Reduction in mRNA Optimization Time Using AI-Powered Platform
Sensible Biotechnologies has reduced mRNA optimization cycles from 15 days to just one day using NVIDIA-powered AI technology, representing a more than 90% time reduction.
Mirvie's RNA Blood Test Predicts Preeclampsia Risk Months Before Symptoms in Major Study
Mirvie's blood test successfully identified 91% of preterm preeclampsia cases in women over 35 without pre-existing conditions, using RNA signatures detectable at 17.5-22 weeks gestation.
Cofactor Genomics' AI-Powered RNA Platform Shows 300-400% Improvement in Predicting Cancer Immunotherapy Response
Cofactor Genomics' OncoPrism platform demonstrates 300-400% improvement in predicting patient responses to cancer immunotherapies compared to other clinical tests using AI and RNA expression data.
N4 Pharma Assembles Expert Leadership Team to Advance Nuvec® Gene Delivery Platform
N4 Pharma has formed a new Senior Leadership Team comprising four experienced consultants with over 25 years each in drug development, manufacturing, and commercialization to advance its Nuvec® gene delivery platform.
New Cryogenic Mass Spectrometry Method Reveals Lipid Nanoparticle Structure, Advancing RNA Therapeutics
Scientists at the University of Nottingham have developed a cryogenic mass spectrometry approach that reveals the precise structure and molecular orientation within lipid nanoparticles used in RNA therapeutics.
Biostate AI Secures $12M Series A to Revolutionize RNA Sequencing and Molecular Diagnostics
Biostate AI has raised $12 million in Series A funding led by Accel to develop affordable RNA sequencing technology and AI-powered diagnostic models.
Oligo Factory Expands Capabilities with New Low-Scale Synthesis Platform for Therapeutic and Diagnostic Development
Oligo Factory has launched a new low-scale oligonucleotide synthesis capability, enabling researchers to order custom DNA and RNA oligos in volumes as small as 50 nmol while maintaining high quality standards.
Eascra Biotech Secures $100,000 MassVentures Grant for Novel Nanoparticle Drug Delivery Platform
Eascra Biotech has received a $100,000 Stage I SBIR Targeted Technologies grant to advance their Janus Base Nanoparticles (JBNps) delivery platform for hard-to-reach tissues.