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Avidity Biosciences

Avidity Biosciences logo
🇺🇸United States
Ownership
Public
Established
2013-01-01
Employees
253
Market Cap
$5.1B
Website
http://www.aviditybiosciences.com
Introduction

Avidity Biosciences, Inc. engages in the development of a new class of oligonucleotide-based therapies called Antibody Oligonucleotide Conjugates (AOC). It utilizes its AOC platform to design, engineer, and develop therapeutics that combine the tissue selectivity of monoclonal antibodies and the precision of oligonucleotide-based therapies in order to access previously undruggable tissue and cell types and more effectively target underlying genetic drivers of diseases. The company was founded by Troy E. Wilson, Kent Hawryluk, Mark E. Davis, and Francis Patrick McCormick on November 13, 2012 and is headquartered in San Diego, CA.

Clinical Trials

10

Active:3
Completed:2

Trial Phases

3 Phases

Phase 1:3
Phase 2:3
Phase 3:3

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (9 trials with phase data)• Click on a phase to view related trials

Phase 1
3 (33.3%)
Phase 2
3 (33.3%)
Phase 3
3 (33.3%)

A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD

Phase 3
Recruiting
Conditions
Facioscapulohumeral Muscular Dystrophy
FSHD
FSHD - Facioscapulohumeral Muscular Dystrophy
FSHD1
FSHD2
Fascioscapulohumeral Muscular Dystrophy
Fascioscapulohumeral Muscular Dystrophy Type 1
Fascioscapulohumeral Muscular Dystrophy Type 2
Facioscapulohumeral Muscular Dystrophy 1
Facioscapulohumeral Dystrophy
Interventions
Drug: Placebo
First Posted Date
2025-06-26
Last Posted Date
2025-06-26
Lead Sponsor
Avidity Biosciences, Inc.
Target Recruit Count
200
Registration Number
NCT07038200
Locations
🇺🇸

University of California Irvine, Orange, California, United States

🇺🇸

Stanford University, Palo Alto, California, United States

🇺🇸

University of Colorado, Denver, Colorado, United States

and more 10 locations

Global Open-Label Extension Study of Del-desiran for the Treatment of DM1

Phase 3
Not yet recruiting
Conditions
Myotonic Dystrophy Type 1
DM1
Myotonia
Myotonic Dystrophy 1
Myotonic Dystrophy
Myotonic Disorders
Steinert Myotonic Dystrophy
Steinert's Disease
Interventions
Drug: Del-desiran (AOC 1001)
First Posted Date
2025-06-06
Last Posted Date
2025-06-06
Lead Sponsor
Avidity Biosciences, Inc.
Target Recruit Count
217
Registration Number
NCT07008469

Phase 2 Open-label Extension Study of AOC 1020 in Participants with Facioscapulohumeral Muscular Dystrophy (FSHD)

Phase 2
Conditions
FSHD
FSHD1
FSHD2
FMD
FMD2
Fascioscapulohumeral Muscular Dystrophy
Fascioscapulohumeral Muscular Dystrophy Type 1
Fascioscapulohumeral Muscular Dystrophy Type 2
Dystrophies, Facioscapulohumeral Muscular
Dystrophy, Facioscapulohumeral Muscular
Interventions
First Posted Date
2024-08-09
Last Posted Date
2024-12-20
Lead Sponsor
Avidity Biosciences, Inc.
Target Recruit Count
84
Registration Number
NCT06547216
Locations
🇺🇸

University of California Los Angeles, Los Angeles, California, United States

🇺🇸

Stanford University, Palo Alto, California, United States

🇺🇸

University of California San Diego, San Diego, California, United States

and more 14 locations

Global Study of Del-desiran for the Treatment of DM1

Phase 3
Recruiting
Conditions
Myotonic Dystrophy 1
Myotonic Disorders
DM1
Myotonic Dystrophy
Steinert
Dystrophy Myotonic
Steinert Disease
Myotonic Muscular Dystrophy
Myotonia
Myotonic Dystrophy Type 1 (DM1)
Interventions
Drug: AOC 1001 (del-desiran)
Drug: Placebo
First Posted Date
2024-05-13
Last Posted Date
2025-05-25
Lead Sponsor
Avidity Biosciences, Inc.
Target Recruit Count
150
Registration Number
NCT06411288
Locations
🇺🇸

Stanford University, Stanford, California, United States

🇺🇸

University of Colorado, Denver, Colorado, United States

🇺🇸

University of Florida, Gainesville, Florida, United States

and more 31 locations

Ph2 Open-label Study of AOC 1044 in Duchenne Muscular Dystrophy Participants With Mutations Amenable to Exon44 Skipping

Phase 2
Active, not recruiting
Conditions
DMD
Duchenne Muscular Dystrophy
Duchenne
Exon 44
Interventions
First Posted Date
2024-02-06
Last Posted Date
2025-05-14
Lead Sponsor
Avidity Biosciences, Inc.
Target Recruit Count
39
Registration Number
NCT06244082
Locations
🇺🇸

Arkansas Children's Hospital, Little Rock, Arkansas, United States

🇺🇸

University of California, San Diego, Rady's Children's Hospital, La Jolla, California, United States

🇺🇸

UC Davis Medical Center, Sacramento, California, United States

and more 7 locations
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Oligo Factory Expands Capabilities with New Low-Scale Synthesis Platform for Therapeutic and Diagnostic Development

Oligo Factory has launched a new low-scale oligonucleotide synthesis capability, enabling researchers to order custom DNA and RNA oligos in volumes as small as 50 nmol while maintaining high quality standards.

Eascra Biotech Secures $100,000 MassVentures Grant for Novel Nanoparticle Drug Delivery Platform

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