St. Jude Children's Research Hospital

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1962-01-01

Employees: -

Market Cap: -

Website: http://www.stjude.org/

Clinical Trials

An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

Phase 2

Recruiting

Conditions: Adult Children
PreDiabetes

Interventions: Drug: Metformin
Behavioral: Digital Intervention

First Posted Date: 2021-02-08

Last Posted Date: 2024-08-12

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 100

Registration Number: NCT04742751

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer

Phase 2

Recruiting

Conditions: Frailty
Childhood Cancer

Interventions: Drug: Dasatinib plus Quercetin
Drug: Fisetin

First Posted Date: 2021-02-02

Last Posted Date: 2024-12-05

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 60

Registration Number: NCT04733534

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Telehealth Based Intervention to Improve Functional Capacity in Survivors of Childhood Cancer With Significantly Limited Exercise Tolerance

Not Applicable

Active, not recruiting

Conditions: Mobility Limitation
Childhood Cancer

Interventions: Other: Exercise testing results
Other: Generalized exercise recommendations (AC)
Other: Individually tailored exercise program (INT)

First Posted Date: 2021-01-19

Last Posted Date: 2024-11-26

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 160

Registration Number: NCT04714840

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Discarded Bone Marrow for Hematology Research

Recruiting

Conditions: Hemoglobinopathies

First Posted Date: 2020-12-17

Last Posted Date: 2024-10-26

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 50

Registration Number: NCT04671212

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Haploidentical HCT for Severe Aplastic Anemia

Phase 2

Recruiting

Conditions: Aplastic Anemia
Bone Marrow Failure Syndrome

Interventions: Drug: Anti-Thymocyte Globulin (Rabbit)
Drug: Fludarabine
Drug: Cyclophosphamide
Drug: Mesna
Drug: G-CSF
Radiation: Total Lymphoid Irradiation (TLI)
Device: CliniMACS
Biological: HPC, A Infusion
Biological: CD45RA-depleted DLI

First Posted Date: 2020-09-22

Last Posted Date: 2024-10-16

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 21

Registration Number: NCT04558736

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Use Of A Response-Adapted Ruxolitinib-Containing Regimen For The Treatment Of Hemophagocytic Lymphohistiocytosis

Phase 1

Active, not recruiting

Conditions: Hemophagocytic Lymphohistiocytosis

Interventions: Drug: Ruxolitinib
Drug: Dexamethasone
Drug: Etoposide

First Posted Date: 2020-09-16

Last Posted Date: 2024-08-28

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 62

Registration Number: NCT04551131

Locations: 🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States
🇺🇸
John Hopkins University, Baltimore, Maryland, United States
🇺🇸
Texas Children's Hospital, Houston, Texas, United States

and more 10 locations

Sickle Cell Disease and the Genomic and Gene Therapy Needs of Stakeholders

Completed

Conditions: Sickle Cell Disease

First Posted Date: 2020-06-04

Last Posted Date: 2024-07-15

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 300

Registration Number: NCT04416178

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Tranexamic Acid Use to Reduce Blood Transfusion in Pediatric Cancer Patients Undergoing Limb Salvage Procedure

Phase 3

Terminated

Conditions: Cancer of the Bone
Limb Salvage

Interventions: Other: 0.9% sodium chloride
Drug: Tranexamic Acid

First Posted Date: 2020-06-01

Last Posted Date: 2024-12-20

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 15

Registration Number: NCT04410042

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Hypertension Intervention to Reduce Osteonecrosis in Children With Acute Lymphoblastic Leukemia/Lymphoma

Phase 2

Active, not recruiting

Conditions: Osteonecrosis
Hypertension
Osteonecrosis Due to Drug

Interventions: Drug: Intensive Antihypertensive Therapy
Drug: Conventional Antihypertensive Therapy
Other: Symptom Survey
Other: Semi-structured interview

First Posted Date: 2020-05-26

Last Posted Date: 2024-12-13

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 51

Registration Number: NCT04401267

Locations: 🇺🇸
St. Jude Affiliate Clinic - Novant Health Hemby Children's Hospital, Charlotte, North Carolina, United States
🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Risk Factors, Clinical Characteristics and Outcomes of Acute Infection With Coronavirus 2019 (COVID-19) In Children

Recruiting

Conditions: Adult Children
Cancer
Corona Virus Infection
Pediatric Cancer

First Posted Date: 2020-05-01

Last Posted Date: 2024-11-27

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 400

Registration Number: NCT04371315

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

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