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GENENTECH, INC.

GENENTECH, INC. logo
πŸ‡ΊπŸ‡ΈUnited States
Ownership
Subsidiary
Established
1976-01-01
Employees
11.1K
Market Cap
-
Website
http://www.gene.com

A Study of GDC-9545 Alone or in Combination With Palbociclib and/or Luteinizing Hormone-Releasing Hormone (LHRH) Agonist in Locally Advanced or Metastatic Estrogen Receptor-Positive Breast Cancer

Phase 1
Active, not recruiting
Conditions
Breast Cancer
Interventions
First Posted Date
2017-11-06
Last Posted Date
2025-02-27
Lead Sponsor
Genentech, Inc.
Target Recruit Count
181
Registration Number
NCT03332797
Locations
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Hospital Quiron Barcelona, Barcelona, Spain

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Hospital Universitari Vall d'Hebron, Barcelona, Spain

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Hospital General Universitario Gregorio Maranon, Madrid, Spain

and more 20 locations

A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy

Phase 1
Completed
Conditions
Leukemia, Myeloid, Acute
Interventions
First Posted Date
2017-10-02
Last Posted Date
2019-11-19
Lead Sponsor
Genentech, Inc.
Target Recruit Count
19
Registration Number
NCT03298516
Locations
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Columbia University Medical Center; Research Pharmacy, Irving Pavillion, Ip 7-749, New York, New York, United States

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Jewish General Hospital / McGill University, Montreal, Quebec, Canada

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University of Alberta Hospital, Edmonton, Alberta, Canada

and more 5 locations

Safety and Tolerability Study of RO7171009 in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)

Phase 1
Completed
Conditions
Geographic Atrophy
Interventions
First Posted Date
2017-09-28
Last Posted Date
2020-02-12
Lead Sponsor
Genentech, Inc.
Target Recruit Count
28
Registration Number
NCT03295877
Locations
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Retina Specialty Institute, Pensacola, Florida, United States

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California Retina Consultants - Santa Maria, Santa Maria, California, United States

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Retina Consultants of Southern Colorado PC; Clinical Research Department, Colorado Springs, Colorado, United States

and more 9 locations

A Study to Investigate the Effect of Formulation, Food, and Rabeprazole on the Pharmacokinetics (PK) of GDC-0853 in Healthy Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2017-09-25
Last Posted Date
2019-09-11
Lead Sponsor
Genentech, Inc.
Target Recruit Count
63
Registration Number
NCT03290703
Locations
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Quotient Clinical Ltd, Clinical Research Unit, Nottingham, United Kingdom

A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

Phase 1
Active, not recruiting
Conditions
Melanoma
Triple Negative Breast Cancer
Renal Cancer
Bladder Cancer
Colorectal Cancer
Non-Small Cell Lung Cancer
Other Solid Cancers
Head and Neck Cancer
Interventions
First Posted Date
2017-09-21
Last Posted Date
2025-04-24
Lead Sponsor
Genentech, Inc.
Target Recruit Count
272
Registration Number
NCT03289962
Locations
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Dana Farber Can Ins, Boston, Massachusetts, United States

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The Ottawa Hospital Cancer Centre, Ottawa, Ontario, Canada

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Princess Margaret Cancer Center, Toronto, Ontario, Canada

and more 23 locations

A Study to Evaluate the Efficacy and Safety of Semorinemab in Patients With Prodromal to Mild Alzheimer's Disease

Phase 2
Terminated
Conditions
Alzheimer's Disease
Interventions
First Posted Date
2017-09-20
Last Posted Date
2022-03-16
Lead Sponsor
Genentech, Inc.
Target Recruit Count
457
Registration Number
NCT03289143
Locations
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M.A. - LEK A.M.Maciejowscy SC., Katowice, Poland

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Novo-Med Zielinski i wspolnicy Sp. j., Katowice, Poland

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AMED Medical Center, Warszawa, Poland

and more 130 locations

Dose-Escalation Study of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)

Phase 1
Active, not recruiting
Conditions
Multiple Myeloma
Interventions
First Posted Date
2017-09-07
Last Posted Date
2025-02-24
Lead Sponsor
Genentech, Inc.
Target Recruit Count
420
Registration Number
NCT03275103
Locations
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Clinica Universidad de Navarra, Pamplona/iruΓ±a, Navarra, Spain

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Hospital Clinico Universitario de Salamanca, Salamanca, Spain

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Jewish General Hospital, Montreal, Quebec, Canada

and more 14 locations

Bioavailability of GDC-0134 and the Effect of Food and Proton Pump Inhibitor on Pharmacokinetics of GDC-0134 in Healthy Female Participants

Phase 1
Completed
Conditions
Amyotrophic Lateral Sclerosis
Interventions
First Posted Date
2017-08-02
Last Posted Date
2024-03-01
Lead Sponsor
Genentech, Inc.
Target Recruit Count
18
Registration Number
NCT03237741
Locations
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Quotient Clinical Ltd, Clinical Research Unit, Nottingham, United Kingdom

A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin

First Posted Date
2017-06-02
Last Posted Date
2019-09-24
Lead Sponsor
Genentech, Inc.
Target Recruit Count
63
Registration Number
NCT03174041
Locations
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Covance Research Unit - Daytona, Daytona Beach, Florida, United States

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Covance Clinical Research Unit Inc.; Covance Gfi Research, Evansville, Indiana, United States

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Covance Clinical Research Unit, Inc, Madison, Wisconsin, United States

Study to Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Participants With Staphylococcus Aureus Bacteremia Receiving Standard-of-Care (SOC) Antibiotics

Phase 1
Completed
Conditions
Bacteremia
Interventions
Drug: Placebo
Drug: SOC
First Posted Date
2017-05-22
Last Posted Date
2020-01-22
Lead Sponsor
Genentech, Inc.
Target Recruit Count
27
Registration Number
NCT03162250
Locations
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Asan Medical Center - Oncology, Seoul, Korea, Republic of

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Korea University Guro Hospital, Seoul, Korea, Republic of

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Henry Ford Health System, Detroit, Michigan, United States

and more 13 locations
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