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GENENTECH, INC.

GENENTECH, INC. logo
๐Ÿ‡บ๐Ÿ‡ธUnited States
Ownership
Subsidiary
Established
1976-01-01
Employees
11.1K
Market Cap
-
Website
http://www.gene.com

Study of Emicizumab Prophylaxis in Participants With Hemophilia A With or Without Inhibitors Undergoing Minor Surgical Procedures

Phase 4
Terminated
Conditions
Hemophilia A
Interventions
First Posted Date
2017-12-04
Last Posted Date
2021-03-01
Lead Sponsor
Genentech, Inc.
Target Recruit Count
14
Registration Number
NCT03361137
Locations
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Childrens Hospital of LA, Los Angeles, California, United States

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Indiana Hemophilia & Thrombosis center, Indianapolis, Indiana, United States

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Newark Beth Israel Medical Center, Newark, New Jersey, United States

and more 5 locations

A Study of Ipatasertib in Participants With Mild, Moderate or Severe Hepatic Impairment Compared to Healthy Participants

Phase 1
Completed
Conditions
Hepatic Insufficiency
Interventions
First Posted Date
2017-11-14
Last Posted Date
2019-11-18
Lead Sponsor
Genentech, Inc.
Target Recruit Count
29
Registration Number
NCT03341884
Locations
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American Research Corporation Inc., San Antonio, Texas, United States

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Clinical Pharmacology of Miami, Inc., Miami, Florida, United States

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New Orleans Center for Clinical Research, Knoxville, Tennessee, United States

A Study of GDC-9545 Alone or in Combination With Palbociclib and/or Luteinizing Hormone-Releasing Hormone (LHRH) Agonist in Locally Advanced or Metastatic Estrogen Receptor-Positive Breast Cancer

Phase 1
Active, not recruiting
Conditions
Breast Cancer
Interventions
First Posted Date
2017-11-06
Last Posted Date
2025-05-28
Lead Sponsor
Genentech, Inc.
Target Recruit Count
181
Registration Number
NCT03332797
Locations
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Hospital Quiron Barcelona, Barcelona, Spain

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Hospital Universitari Vall d'Hebron, Barcelona, Spain

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Hospital General Universitario Gregorio Maranon, Madrid, Spain

and more 20 locations

A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy

Phase 1
Completed
Conditions
Leukemia, Myeloid, Acute
Interventions
First Posted Date
2017-10-02
Last Posted Date
2019-11-19
Lead Sponsor
Genentech, Inc.
Target Recruit Count
19
Registration Number
NCT03298516
Locations
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Columbia University Medical Center; Research Pharmacy, Irving Pavillion, Ip 7-749, New York, New York, United States

๐Ÿ‡จ๐Ÿ‡ฆ

Jewish General Hospital / McGill University, Montreal, Quebec, Canada

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University of Alberta Hospital, Edmonton, Alberta, Canada

and more 5 locations

Safety and Tolerability Study of RO7171009 in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)

Phase 1
Completed
Conditions
Geographic Atrophy
Interventions
First Posted Date
2017-09-28
Last Posted Date
2020-02-12
Lead Sponsor
Genentech, Inc.
Target Recruit Count
28
Registration Number
NCT03295877
Locations
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Retina Specialty Institute, Pensacola, Florida, United States

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California Retina Consultants - Santa Maria, Santa Maria, California, United States

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Retina Consultants of Southern Colorado PC; Clinical Research Department, Colorado Springs, Colorado, United States

and more 9 locations

A Study to Investigate the Effect of Formulation, Food, and Rabeprazole on the Pharmacokinetics (PK) of GDC-0853 in Healthy Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2017-09-25
Last Posted Date
2019-09-11
Lead Sponsor
Genentech, Inc.
Target Recruit Count
63
Registration Number
NCT03290703
Locations
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Quotient Clinical Ltd, Clinical Research Unit, Nottingham, United Kingdom

A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

Phase 1
Active, not recruiting
Conditions
Melanoma
Triple Negative Breast Cancer
Renal Cancer
Bladder Cancer
Colorectal Cancer
Non-Small Cell Lung Cancer
Other Solid Cancers
Head and Neck Cancer
Interventions
First Posted Date
2017-09-21
Last Posted Date
2025-04-24
Lead Sponsor
Genentech, Inc.
Target Recruit Count
272
Registration Number
NCT03289962
Locations
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Dana Farber Can Ins, Boston, Massachusetts, United States

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The Ottawa Hospital Cancer Centre, Ottawa, Ontario, Canada

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Princess Margaret Cancer Center, Toronto, Ontario, Canada

and more 23 locations

A Study to Evaluate the Efficacy and Safety of Semorinemab in Patients With Prodromal to Mild Alzheimer's Disease

Phase 2
Terminated
Conditions
Alzheimer's Disease
Interventions
First Posted Date
2017-09-20
Last Posted Date
2022-03-16
Lead Sponsor
Genentech, Inc.
Target Recruit Count
457
Registration Number
NCT03289143
Locations
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M.A. - LEK A.M.Maciejowscy SC., Katowice, Poland

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Novo-Med Zielinski i wspolnicy Sp. j., Katowice, Poland

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AMED Medical Center, Warszawa, Poland

and more 130 locations

Dose-Escalation Study of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)

Phase 1
Active, not recruiting
Conditions
Multiple Myeloma
Interventions
First Posted Date
2017-09-07
Last Posted Date
2025-05-23
Lead Sponsor
Genentech, Inc.
Target Recruit Count
420
Registration Number
NCT03275103
Locations
๐Ÿ‡ช๐Ÿ‡ธ

Clinica Universidad de Navarra, Pamplona/iruรฑa, Navarra, Spain

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Hospital Clinico Universitario de Salamanca, Salamanca, Spain

๐Ÿ‡จ๐Ÿ‡ฆ

Jewish General Hospital, Montreal, Quebec, Canada

and more 14 locations

Bioavailability of GDC-0134 and the Effect of Food and Proton Pump Inhibitor on Pharmacokinetics of GDC-0134 in Healthy Female Participants

Phase 1
Completed
Conditions
Amyotrophic Lateral Sclerosis
Interventions
First Posted Date
2017-08-02
Last Posted Date
2024-03-01
Lead Sponsor
Genentech, Inc.
Target Recruit Count
18
Registration Number
NCT03237741
Locations
๐Ÿ‡ฌ๐Ÿ‡ง

Quotient Clinical Ltd, Clinical Research Unit, Nottingham, United Kingdom

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