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GENENTECH, INC.

GENENTECH, INC. logo
🇺🇸United States
Ownership
Subsidiary
Established
1976-01-01
Employees
11.1K
Market Cap
-
Website
http://www.gene.com

A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin

First Posted Date
2017-06-02
Last Posted Date
2019-09-24
Lead Sponsor
Genentech, Inc.
Target Recruit Count
63
Registration Number
NCT03174041
Locations
🇺🇸

Covance Research Unit - Daytona, Daytona Beach, Florida, United States

🇺🇸

Covance Clinical Research Unit Inc.; Covance Gfi Research, Evansville, Indiana, United States

🇺🇸

Covance Clinical Research Unit, Inc, Madison, Wisconsin, United States

Study to Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Participants With Staphylococcus Aureus Bacteremia Receiving Standard-of-Care (SOC) Antibiotics

Phase 1
Completed
Conditions
Bacteremia
Interventions
Drug: Placebo
Drug: SOC
First Posted Date
2017-05-22
Last Posted Date
2020-01-22
Lead Sponsor
Genentech, Inc.
Target Recruit Count
27
Registration Number
NCT03162250
Locations
🇰🇷

Asan Medical Center - Oncology, Seoul, Korea, Republic of

🇰🇷

Korea University Guro Hospital, Seoul, Korea, Republic of

🇺🇸

Henry Ford Health System, Detroit, Michigan, United States

and more 13 locations

An Expanded Access Program of Emicizumab in Participants With Hemophilia A With Inhibitors

Conditions
Hemophilia A
First Posted Date
2017-05-16
Last Posted Date
2018-03-29
Lead Sponsor
Genentech, Inc.
Registration Number
NCT03154437
Locations
🇺🇸

Tulane Medical Center; Investigational/Research Pharmacy, New Orleans, Louisiana, United States

🇺🇸

Children's Mercy Hosp Clinics, Kansas City, Missouri, United States

🇺🇸

University of Texas Medical School, Houston, Texas, United States

and more 11 locations

A Study of GDC-0853 in Participants With Refractory Chronic Spontaneous Urticaria (CSU).

Phase 2
Completed
Conditions
Urticaria
Interventions
Drug: Placebo
First Posted Date
2017-05-02
Last Posted Date
2020-09-29
Lead Sponsor
Genentech, Inc.
Target Recruit Count
134
Registration Number
NCT03137069
Locations
🇨🇦

Gordon Sussman Clinical Research, Toronto, Ontario, Canada

🇺🇸

New Horizon Research Center, Miami, Florida, United States

🇩🇪

Universitätsmedizin Johannes Gutenberg Universität, Mainz, Germany

and more 24 locations

A Multiple Ascending Dose Study to Evaluate Safety and Tolerability of BFKB8488A in Participants With Type 2 Diabetes Mellitus and Participants With Non-Alcoholic Fatty Liver Disease

Phase 1
Completed
Conditions
Diabetes Mellitus, Type 2
Non-Alcoholic Fatty Liver Disease
Interventions
Other: Placebo
First Posted Date
2017-02-23
Last Posted Date
2020-03-27
Lead Sponsor
Genentech, Inc.
Target Recruit Count
154
Registration Number
NCT03060538
Locations
🇺🇸

MD Clinical, Hallandale Beach, Florida, United States

🇺🇸

MidWest Clinical Research, Overland Park, Kansas, United States

🇺🇸

Premier Research Associate, Inc, Miami, Florida, United States

and more 15 locations

A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-Based Therapy

Phase 2
Terminated
Conditions
Urothelial Carcinoma
Interventions
First Posted Date
2017-01-24
Last Posted Date
2019-05-31
Lead Sponsor
Genentech, Inc.
Target Recruit Count
5
Registration Number
NCT03029832
Locations
🇺🇸

Arizona Oncology - HOPE Wilmot, Tucson, Arizona, United States

🇺🇸

Nebraska Methodist Hospital; Cancer Center, Omaha, Nebraska, United States

🇺🇸

University of Colorado, Denver, Colorado, United States

and more 19 locations

To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer

Phase 1
Active, not recruiting
Conditions
Breast Cancer
Solid Tumor
Interventions
First Posted Date
2016-12-30
Last Posted Date
2025-03-18
Lead Sponsor
Genentech, Inc.
Target Recruit Count
200
Registration Number
NCT03006172
Locations
🇫🇷

Institut Gustave Roussy, Villejuif, France

🇬🇧

Royal Marsden Hospital - Surrey, Surrey, Sutton, United Kingdom

🇬🇧

Royal Marsden Hospital - London, London, United Kingdom

and more 6 locations

A Study to Compare Pharmacokinetics (PK) of Etrolizumab Administered Subcutaneously by a Prefilled Syringe With Needle Safety Device (PFS-NSD) or an Auto-injector (AI)

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Device: Auto-Injector (AI)
Device: Prefilled Syringe With Needle Safety Device (PFS-NSD)
First Posted Date
2016-12-19
Last Posted Date
2018-12-03
Lead Sponsor
Genentech, Inc.
Target Recruit Count
180
Registration Number
NCT02996019
Locations
🇺🇸

Covance Research Unit - Daytona, Daytona Beach, Florida, United States

🇺🇸

Covance Clinical Research Unit Inc.; Covance Gfi Research, Evansville, Indiana, United States

🇺🇸

Covance Clinical Research Unit, Inc, Madison, Wisconsin, United States

and more 1 locations

A Study to Evaluate the Long-Term Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Rheumatoid Arthritis Enrolled in Study GA29350

Phase 2
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2016-12-06
Last Posted Date
2020-08-03
Lead Sponsor
Genentech, Inc.
Target Recruit Count
496
Registration Number
NCT02983227
Locations
🇺🇦

CNI Consultative and Diagnostic Center of Desnianskyi District of Kyiv, Kyiv, Ukraine

🇵🇱

Centrum Medyczne Pratia Katowice I, Katowice, Poland

🇵🇱

CCBR - Lodz - PL, Lodz, Poland

and more 101 locations

A Study of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Resectable Non-Small Cell Lung Cancer (NSCLC) - Lung Cancer Mutation Consortium (LCMC3)

Phase 2
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2016-10-07
Last Posted Date
2024-01-26
Lead Sponsor
Genentech, Inc.
Target Recruit Count
181
Registration Number
NCT02927301
Locations
🇺🇸

City of Hope Comprehensive Cancer Center, Duarte, California, United States

🇺🇸

UCLA Cancer Center, Santa Monica, California, United States

🇺🇸

University Of Colorado, Aurora, Colorado, United States

and more 16 locations
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