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M.D. ANDERSON CANCER CENTER

🇺🇸United States
Ownership
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Employees
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Market Cap
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Website

Metformin and Nightly Fasting in Women With Early Breast Cancer

Phase 2
Recruiting
Conditions
Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Breast Ductal Carcinoma In Situ
Invasive Breast Carcinoma
Interventions
Procedure: Biospecimen Collection
Drug: Extended Release Metformin Hydrochloride
Other: Monitoring
Other: Nutritional Assessment
Other: Short-Term Fasting
First Posted Date
2021-08-27
Last Posted Date
2024-06-21
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
120
Registration Number
NCT05023967
Locations
🇮🇹

Galliera Hospital, Genoa, Italy

🇮🇹

European Institute of Oncology, Milano, Italy

🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

ALX148, Rituximab and Lenalidomide for the Treatment of Indolent and Aggressive B-cell Non-Hodgkin Lymphoma

Phase 1
Active, not recruiting
Conditions
Ann Arbor Stage III Marginal Zone Lymphoma
Refractory Follicular Lymphoma
Ann Arbor Stage III Grade 3 Follicular Lymphoma
Refractory High Grade B-Cell Lymphoma
Refractory Mantle Cell Lymphoma
Ann Arbor Stage III Grade 2 Follicular Lymphoma
Ann Arbor Stage IV Grade 3 Follicular Lymphoma
Refractory Aggressive B-Cell Non-Hodgkin Lymphoma
Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
Aggressive B-Cell Non-Hodgkin Lymphoma
Interventions
Drug: CD47 Antagonist ALX148
First Posted Date
2021-08-27
Last Posted Date
2025-04-24
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
47
Registration Number
NCT05025800
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Sintilimab in Cancer of Unknown Primary

Phase 2
Completed
Conditions
Cancer of Unknown Primary Site
Interventions
First Posted Date
2021-08-27
Last Posted Date
2025-04-27
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
12
Registration Number
NCT05024968
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Evaluating Shared Decision-Making for Lung Cancer Screening Among Chinese Populations in the United States

Withdrawn
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Procedure: Discussion
Other: Interview
First Posted Date
2021-08-27
Last Posted Date
2024-03-15
Lead Sponsor
M.D. Anderson Cancer Center
Registration Number
NCT05024955

Exercise During Chemotherapy in Older Women With Stage I-III Breast Cancer

Not Applicable
Active, not recruiting
Conditions
Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage IA Breast Cancer AJCC v8
Anatomic Stage IB Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage IIA Breast Cancer AJCC v8
Anatomic Stage IIB Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IIIA Breast Cancer AJCC v8
Anatomic Stage IIIB Breast Cancer AJCC v8
Anatomic Stage IIIC Breast Cancer AJCC v8
Interventions
Procedure: Discussion
Other: Exercise Intervention
Other: Informational Intervention
Other: Medical Device Usage and Evaluation
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
First Posted Date
2021-08-27
Last Posted Date
2025-03-30
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
30
Registration Number
NCT05025059
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

The Impact of COVID-19 on Pulmonary Procedures

Recruiting
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
COVID-19 Infection
Malignant Solid Neoplasm
Interventions
Other: Survey Administration
First Posted Date
2021-08-26
Last Posted Date
2025-01-28
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
250
Registration Number
NCT05022446
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Sapanisertib and Nivolumab for the Treatment of Stage I-IV Non-small Cell Lung Cancer in Patients Who Have Progressed on Prior PD-1/PD-L1 Inhibitor Therapy, I-OVERCOME Study

Phase 1
Withdrawn
Conditions
Lung Non-Small Cell Carcinoma
Stage I Lung Cancer AJCC v8
Stage II Lung Cancer AJCC v8
Stage IIA Lung Cancer AJCC v8
Recurrent Lung Non-Small Cell Carcinoma
Stage III Lung Cancer AJCC v8
Stage IIIA Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8
Stage IVA Lung Cancer AJCC v8
Stage IIB Lung Cancer AJCC v8
Interventions
Biological: Nivolumab
First Posted Date
2021-08-26
Last Posted Date
2022-05-27
Lead Sponsor
M.D. Anderson Cancer Center
Registration Number
NCT05022394

Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcoma, TACOS Study

Phase 2
Recruiting
Conditions
Metastatic Osteosarcoma
Locally Advanced Osteosarcoma
Refractory Osteosarcoma
Recurrent Osteosarcoma
Unresectable Osteosarcoma
Interventions
First Posted Date
2021-08-25
Last Posted Date
2025-04-25
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
40
Registration Number
NCT05019703
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Aurora Kinase Inhibitor LY3295668 in Combination With Osimertinib for the Treatment of Advanced or Metastatic EGFR-Mutant Non-squamous Non-small Cell Lung Cancer

Phase 1
Active, not recruiting
Conditions
Advanced Lung Non-Squamous Non-Small Cell Carcinoma
Metastatic Lung Non-Squamous Non-Small Cell Carcinoma
Stage III Lung Cancer AJCC v8
Stage IIIA Lung Cancer AJCC v8
Stage IIIB Lung Cancer AJCC v8
Stage IIIC Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8
Stage IVA Lung Cancer AJCC v8
Stage IVB Lung Cancer AJCC v8
Interventions
First Posted Date
2021-08-23
Last Posted Date
2025-05-21
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
32
Registration Number
NCT05017025
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Sintilimab for the Treatment of Locally Advanced, Metastatic, Recurrent, or Unresectable Undifferentiated Pleomorphic Sarcoma, SiARa Cancer Study

Phase 2
Terminated
Conditions
Metastatic Undifferentiated Pleomorphic Sarcoma
Locally Advanced Undifferentiated Pleomorphic Sarcoma
Recurrent Undifferentiated Pleomorphic Sarcoma
Unresectable Undifferentiated Pleomorphic Sarcoma
Interventions
First Posted Date
2021-08-23
Last Posted Date
2024-12-11
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
6
Registration Number
NCT05017103
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

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