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NeuroSense Therapeutics

NeuroSense Therapeutics logo
🇺🇸United States
Ownership
Public
Established
2017-01-01
Employees
16
Market Cap
-
Website
http://www.neurosense-tx.com

Clinical Trials

6

Active:1
Completed:4

Trial Phases

2 Phases

Phase 1:3
Phase 2:3

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (6 trials with phase data)• Click on a phase to view related trials

Phase 1
3 (50.0%)
Phase 2
3 (50.0%)

A Phase 2, Randomized, Prospective Double-Blind, Single-Center, Placebo-controlled Study to Evaluate Safety, Tolerability, Target Engagement, and Efficacy of PrimeC in Patients With Mild to Moderate Alzheimer's Disease.

Phase 2
Recruiting
Conditions
Alzheimer Disease
Interventions
Drug: Placebo
First Posted Date
2023-12-29
Last Posted Date
2024-01-18
Lead Sponsor
NeuroSense Therapeutics Ltd.
Target Recruit Count
20
Registration Number
NCT06185543
Locations
🇮🇱

Rambam Health Care Campus, Haifa, Israel

A Multiple-Dose PK Study to Evaluate the Comparative Bioavailability of PrimeC Tablets to Ciprofloxacin Tablets Co-administered With Celecoxib Capsules, in Healthy Adult Subject

Phase 1
Completed
Conditions
Pharmacokinetics
Interventions
First Posted Date
2022-06-29
Last Posted Date
2023-02-08
Lead Sponsor
NeuroSense Therapeutics Ltd.
Target Recruit Count
19
Registration Number
NCT05436678
Locations
🇺🇸

Novum, Las Vegas, Nevada, United States

A Phase IIb, Multi-Center, Multinational, Double-Blind, Placebo-Controlled Study, With an Open Label Extension, to Evaluate Safety, Tolerability and Efficacy of PrimeC in Subjects With ALS

Phase 2
Active, not recruiting
Conditions
Amyotrophic Lateral Sclerosis
ALS
Interventions
Drug: Placebo
First Posted Date
2022-05-03
Last Posted Date
2023-12-07
Lead Sponsor
NeuroSense Therapeutics Ltd.
Target Recruit Count
69
Registration Number
NCT05357950
Locations
🇨🇦

Lawson Health Research Institute, London, Ontario, Canada

🇮🇱

Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

🇮🇹

IRCCS Istituti clinici Maugeri, Milano, Italy

and more 1 locations

A Pilot Study to Evaluate the PK Profile of PrimeC-ER Tablets in Healthy Adult Subjects

Phase 1
Completed
Conditions
Pharmacokinetics
Interventions
First Posted Date
2022-02-09
Last Posted Date
2022-10-25
Lead Sponsor
NeuroSense Therapeutics Ltd.
Target Recruit Count
12
Registration Number
NCT05232461
Locations
🇺🇸

Novum, Fargo, North Dakota, United States

Open Label Study to Evaluate Ciprofloxacin/Celecoxib Combination in Patients With ALS

Phase 2
Completed
Conditions
Amyotrophic Lateral Sclerosis
ALS
Interventions
Drug: Fixed dose combination Ciprofloxacin/Celecoxib
First Posted Date
2019-11-18
Last Posted Date
2021-03-03
Lead Sponsor
NeuroSense Therapeutics Ltd.
Target Recruit Count
16
Registration Number
NCT04165850
Locations
🇮🇱

Sourasky Medical Center, Tel Aviv, Israel

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News

NeuroSense to Present Promising Phase 2b Data for Novel ALS Drug PrimeC at AAN Meeting

NeuroSense Therapeutics will showcase new data from PrimeC's Phase 2b trial in ALS at the American Academy of Neurology Meeting on April 8, 2025, featuring presentations on clinical outcomes and microRNA biomarker findings.

NeuroSense Therapeutics Regains Nasdaq Compliance Amidst PrimeC Development for ALS

NeuroSense Therapeutics has regained compliance with Nasdaq's minimum equity requirement, ensuring its stock remains listed on the Nasdaq Capital Market.

NeuroSense Therapeutics Advances PrimeC for ALS with Global Pharma Partnership and FDA Guidance

NeuroSense Therapeutics has entered a binding term sheet with a leading global pharmaceutical company for PrimeC development, securing upfront payment and Phase 3 trial funding.

NeuroSense Therapeutics Presents PrimeC Data at ALS/MND Symposium

NeuroSense Therapeutics will present Phase 2b PARADIGM trial results of PrimeC, a potential ALS treatment, at the International Symposium on ALS/MND.

NeuroSense Therapeutics to Discuss Phase 3 Trial of PrimeC for ALS with FDA

NeuroSense Therapeutics will meet with the FDA to discuss the Phase 3 trial design for PrimeC, an experimental therapy for amyotrophic lateral sclerosis (ALS).

NeuroSense to Advance Phase 3 ALS Trial Following FDA Meeting

NeuroSense will meet with the FDA to finalize the Phase 3 trial design for PrimeC, a potential treatment for Amyotrophic Lateral Sclerosis (ALS).

NeuroSense Advances ALS Program with FDA Meeting for PrimeC Phase 3 Trial

NeuroSense has scheduled a Type C meeting with the FDA on November 6, 2024, to finalize the Phase 3 trial design for PrimeC, a potential ALS treatment.

PrimeC Shows Significant Improvement in Key miRNAs for ALS Patients in PARADIGM Trial

NeuroSense Therapeutics' PrimeC demonstrated significant regulation of key microRNAs (miRNAs) in ALS patients, offering a potential disease-modifying treatment.

NeuroSense's PrimeC Demonstrates Efficacy in ALS, Pursues Early Approval in Canada

NeuroSense Therapeutics' PrimeC showed a 36% reduction in ALS disease progression and a 43% improvement in survival rates in clinical trials.

NeuroSense Therapeutics Regains Compliance with NASDAQ, Plans Phase 3 Trial for PrimeC

NeuroSense Therapeutics has regained compliance with Nasdaq's minimum bid price requirement, ensuring continued listing on the exchange.

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