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Murdoch Childrens Research Institute

🇦🇺Australia

Country: 🇦🇺Australia

Ownership: Holding

Established: 1986-01-01

Employees: 1K

Market Cap: -

Website: http://www.mcri.edu.au

Clinical Trials

A Study Investigating the Change in Metabolism Phenotype in Paediatric, Adolescent & Young Adults With Hodgkin or Non-Hodgkin Lymphoma.

Phase 1

Not yet recruiting

Conditions: Hodgkin Lymphoma
Non Hodgkin Lymphoma

First Posted Date: 2024-04-25

Last Posted Date: 2025-05-23

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 10

Registration Number: NCT06383338

Locations: 🇦🇺
Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

Analysing HIgh Dose Probiotic Peanut Oral Immunotherapy (PPOIT) and High Dose Peanut Oral Immunotherapy (OIT) Versus LOw Dose Peanut OIT for Peanut Allergy

Phase 2

Withdrawn

Conditions: Peanut Allergy

Interventions: Drug: Peanut Oral Powder [PEANUT POWDER]
Dietary Supplement: Probiotic (LGG®, Lactobacillus Rhamnosus) or placebo probiotic (maltodextrin)

First Posted Date: 2024-03-06

Last Posted Date: 2024-08-15

Lead Sponsor: Murdoch Childrens Research Institute

Registration Number: NCT06297083

The Egg Up Trial - Testing a New Treatment Pathway for Infants with Newly Diagnosed Egg Allergy

Not Applicable

Active, not recruiting

Conditions: Food Allergy in Infants
Food Allergy

First Posted Date: 2024-02-22

Last Posted Date: 2025-01-24

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 109

Registration Number: NCT06273605

Locations: 🇦🇺
Murdoch Children's Research Institute (MCRI), Melbourne, Victoria, Australia

Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone

Phase 4

Recruiting

Conditions: Patient-Controlled Analgesia

Interventions: Drug: Oxycodone
Drug: Morphine

First Posted Date: 2023-12-29

Last Posted Date: 2024-03-25

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 690

Registration Number: NCT06186141

Locations: 🇦🇺
The Royal Children's Hospital, Melbourne, Victoria, Australia

Health Systems and Policy Contexts of Medical Oxygen

Recruiting

Conditions: Hypoxemia
Morality
Pneumonia

First Posted Date: 2023-12-13

Last Posted Date: 2024-08-29

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 1

Registration Number: NCT06169514

Locations: 🇰🇭
Cambodia, Phnom Penh, Cambodia
🇱🇦
Lao PDR, Vientiane, Lao People's Democratic Republic
🇱🇷
Liberia, Monrovia, Liberia

and more 3 locations

Evaluation of a Multi-country Medical Oxygen Program

Recruiting

Conditions: Hypoxemia
Neonatal Disease
Pneumonia
Sepsis
Morality

First Posted Date: 2023-10-17

Last Posted Date: 2025-06-15

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 1200

Registration Number: NCT06087315

Locations: 🇺🇬
10 Facilities to Be Selected, Kampala, Uganda

A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations

Phase 2

Recruiting

Conditions: Venous Malformation
Slow-Flow Vascular Malformation
Fast-Flow Vascular Malformation
Arteriovenous Malformations
PIK3CA-related Overgrowth Spectrum
Lymphatic Malformation, Low Flow
Lymphatic Malformation
Vascular Anomaly
KRAS G12D
Vascular Malformations

Interventions: Drug: Alpelisib
Drug: Mirdametinib

First Posted Date: 2023-08-09

Last Posted Date: 2025-04-13

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 50

Registration Number: NCT05983159

Locations: 🇦🇺
Peter MacCallum Cancer Centre, Parkville, Victoria, Australia
🇦🇺
The Royal Children's Hospital, Parkville, Victoria, Australia

Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2)

Phase 4

Recruiting

Conditions: Sepsis
Infections
Bacteremia

First Posted Date: 2023-03-15

Last Posted Date: 2025-06-12

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 40

Registration Number: NCT05770622

Locations: 🇦🇺
Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia
🇦🇺
Monash Newborn, Melbourne, Australia
🇦🇺
Royal Hospital for Women, Sydney, Australia

and more 1 locations

Minimising Adverse Drug Reactions and Verifying Economic Legitimacy in Children (MARVEL-PIC)

Not Applicable

Recruiting

Conditions: Bone Marrow Transplantation
Neoplasms

First Posted Date: 2022-12-29

Last Posted Date: 2024-06-21

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 880

Registration Number: NCT05667766

Locations: 🇦🇺
Sydney Children's Hospital, Randwick, New South Wales, Australia
🇦🇺
Women's and Children's Hospital, North Adelaide, South Australia, Australia
🇦🇺
The Royal Children's Hospital, Parkville, Victoria, Australia

and more 1 locations

COVID-19 Booster Study in Healthy Adults in Australia

Phase 3

Active, not recruiting

Conditions: COVID-19

First Posted Date: 2022-12-20

Last Posted Date: 2023-11-01

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 497

Registration Number: NCT05658523

Locations: 🇦🇺
Royal Children's Hospital, Murdoch Children's Research Institute, Melbourne, Victoria, Australia

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