Murdoch Childrens Research Institute

🇦🇺Australia

Country: 🇦🇺Australia

Ownership: Holding

Established: 1986-01-01

Employees: 1K

Market Cap: -

Website: http://www.mcri.edu.au

Clinical Trials

A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations

Phase 2

Recruiting

Conditions: Venous Malformation
Slow-Flow Vascular Malformation
Fast-Flow Vascular Malformation
Arteriovenous Malformations
PIK3CA-related Overgrowth Spectrum
Lymphatic Malformation, Low Flow
Lymphatic Malformation
Vascular Anomaly
KRAS G12D
Vascular Malformations

Interventions: Drug: Alpelisib
Drug: Mirdametinib

First Posted Date: 2023-08-09

Last Posted Date: 2024-11-27

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 50

Registration Number: NCT05983159

Locations: 🇦🇺
Peter MacCallum Cancer Centre, Parkville, Victoria, Australia
🇦🇺
The Royal Children's Hospital, Parkville, Victoria, Australia

Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2)

Phase 4

Recruiting

Conditions: Sepsis
Infections
Bacteremia

Interventions: Other: First-dose trough dose adjustment calculator - using early TDM (first-dose trough) to determine an early dose adjustment if the predicted steady-state trough is outside of target range (10-20mg/L)

First Posted Date: 2023-03-15

Last Posted Date: 2024-11-14

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 40

Registration Number: NCT05770622

Locations: 🇦🇺
Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia
🇦🇺
Monash Newborn, Melbourne, Australia
🇦🇺
Royal Hospital for Women, Sydney, Australia

and more 1 locations

Minimising Adverse Drug Reactions and Verifying Economic Legitimacy in Children (MARVEL-PIC)

Not Applicable

Recruiting

Conditions: Bone Marrow Transplantation
Neoplasms

Interventions: Diagnostic Test: Release of Extended Pharmacogenomics Report at Week 1
Diagnostic Test: Release of Extended Pharmacogenomics Report at Week 13

First Posted Date: 2022-12-29

Last Posted Date: 2024-06-21

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 880

Registration Number: NCT05667766

Locations: 🇦🇺
Perth Children's Hospital, Nedlands, Western Australia, Australia
🇦🇺
Women's and Children's Hospital, North Adelaide, South Australia, Australia
🇦🇺
Sydney Children's Hospital, Randwick, New South Wales, Australia

and more 1 locations

COVID-19 Booster Study in Healthy Adults in Australia

Phase 3

Active, not recruiting

Conditions: COVID-19

Interventions: Biological: Novavax
Biological: Bivalent Moderna

First Posted Date: 2022-12-20

Last Posted Date: 2023-11-01

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 497

Registration Number: NCT05658523

Locations: 🇦🇺
Royal Children's Hospital, Murdoch Children's Research Institute, Melbourne, Victoria, Australia

Beat to Beat A Study in Paediatric, Adolescent and Young Adult Patients Who Are Undergoing or Have Undergone Cancer Therapy to Evaluate the Agreement Between QTc Measured Using 12 Lead Electrocardiogram (ECG) and a Wearable Device ECG

Not Applicable

Active, not recruiting

Conditions: Neoplasms
Cardiac Arrhythmia

Interventions: Device: ECG application
Device: 12 lead ECG

First Posted Date: 2022-11-14

Last Posted Date: 2024-07-08

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 46

Registration Number: NCT05615376

Locations: 🇦🇺
The Royal Children's Hospital, Parkville, Victoria, Australia

Pilot Study of MC in Paediatric Palliative Care

Phase 1

Recruiting

Conditions: Palliative Care

Interventions: Drug: Medicinal Cannabis - C20T5
Drug: Medicinal Cannabis - C12T12

First Posted Date: 2022-11-14

Last Posted Date: 2024-03-13

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 10

Registration Number: NCT05615389

Locations: 🇦🇺
Royal Children's Hospital / Murdoch Children's Research Institute, Parkville, Victoria, Australia

COVID-19 Fourth Dose Study in Australia

Phase 3

Withdrawn

Conditions: COVID-19

Interventions: Biological: Elasomeran
Biological: Tozinameran
Biological: Bivalent Pfizer-BioNTech
Biological: Bivalent Moderna

First Posted Date: 2022-09-16

Last Posted Date: 2024-03-15

Lead Sponsor: Murdoch Childrens Research Institute

Registration Number: NCT05543356

Locations: 🇦🇺
Royal Children's Hospital, Murdoch Children's Research Institute, Melbourne, Victoria, Australia

Automated Versus Manual Control Of Oxygen For Preterm Infants On Continuous Positive Airway Pressure In Nigeria

Not Applicable

Completed

Conditions: Neonatal Respiratory Distress Related Conditions
Neonatal Respiratory Failure
Oxygen Toxicity
Prematurity

Interventions: Other: Manual oxygen control
Device: OxyMate

First Posted Date: 2022-08-19

Last Posted Date: 2023-11-13

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 49

Registration Number: NCT05508308

Locations: 🇳🇬
Sacred Heart Hospital, Lantoro, Abeokuta, Nigeria
🇳🇬
University College Hospital, Agodi, Ibadan, Nigeria

Ivermectin Therapy for Scabies Infection in Children Younger Than 5 Years of Age (ITCHY Study)

Phase 2

Not yet recruiting

Conditions: Scabies; Itch
Scabies

Interventions: Drug: Ivermectin Tablets

First Posted Date: 2022-08-15

Last Posted Date: 2024-04-24

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 120

Registration Number: NCT05500326

Locations: 🇱🇦
Hinngoon Health Centre, Kasy District, Vientiane Province, Lao People's Democratic Republic
🇱🇦
Kasy District Hospital, Kasy District, Vientiane Province, Lao People's Democratic Republic
🇱🇦
ThongMeud Health Centre, Kasy District, Vientiane, Lao People's Democratic Republic

and more 2 locations

Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents

Recruiting

Conditions: Reproductive Health
Noncommunicable Diseases
Obesity
Intergenerational Relations
Infant Health
Health Equity
Quality of Life
Social Determinants of Health
Cognition
Congenital Abnormalities

First Posted Date: 2022-05-27

Last Posted Date: 2024-06-20

Lead Sponsor: Murdoch Childrens Research Institute

Target Recruit Count: 200000

Registration Number: NCT05394363

Locations: 🇦🇺
Murdoch Children's Research Institute, Parkville, Victoria, Australia

© Copyright 2024. All Rights Reserved by MedPath

Home Terms & Conditions Privacy Policy