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HELLENIC INSTITUTE FOR THE STUDY OF SEPSIS

🇬🇷Greece

Country: 🇬🇷Greece

Ownership: Private

Employees: -

Market Cap: -

Website

Clinical Trials

Pulse Photoplethysmography as an Early Tool for the Diagnosis of Sepsis

Completed

Conditions: Sepsis

Interventions: Device: pulse photoplethysmography (PPG)
Diagnostic Test: Measurements of nitric oxide (NO) and malondialdehyde (MDA)

First Posted Date: 2019-11-04

Last Posted Date: 2020-07-29

Lead Sponsor: Hellenic Institute for the Study of Sepsis

Target Recruit Count: 200

Registration Number: NCT04149132

Locations: 🇬🇷
Intensive Care Unit, "Korgialenio - Benakio" General Hospital of Athens, Athens, Greece
🇬🇷
Department of Clinical Therapeutics, "Alexandra" General Hospital of Athens, National and Kapodistrian University of Athens, Medical School, Athens, Greece
🇬🇷
2nd Department of Critical Care, "Attikon" University Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece

and more 1 locations

The Benefit of Bermekimab in Patients With Systemic Sclerosis

Phase 2

Completed

Conditions: Scleroderma, Systemic

Interventions: Drug: MABp1 (Bermekimab) OR Placebo
Drug: MABp1 (Bermekimab)

First Posted Date: 2019-08-06

Last Posted Date: 2022-09-29

Lead Sponsor: Hellenic Institute for the Study of Sepsis

Target Recruit Count: 20

Registration Number: NCT04045743

Locations: 🇬🇷
Department of Pathophysiology, LAIKO Athens General Hospital, Athens, Attiki, Greece
🇬🇷
4th Department of Internal Medicine, ATTIKON University Hospital, Athens, Attiki, Greece

suPAR to Guide Antibiotics in Emergency Department

Phase 2

Conditions: Sepsis

Interventions: Drug: Placebo
Drug: Meropenem

First Posted Date: 2018-10-24

Last Posted Date: 2020-07-30

Lead Sponsor: Hellenic Institute for the Study of Sepsis

Target Recruit Count: 220

Registration Number: NCT03717350

Locations: 🇬🇷
4th Department of Internal Medicine, ATTIKON University Hospital, Athens, Attiki, Greece
🇬🇷
1st Department of Internal Medicine of G. GENNIMATAS General Hospital, Athens, Greece
🇬🇷
3rd Department of Internal Medicine at SOTIRIA General Hospital of Chest Diseases of Athens, Athens, Greece

and more 2 locations

Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune System

Phase 3

Completed

Conditions: Gram-Negative Bacteria Infection
Mortality
Sepsis
Respiratory Distress Syndrome
Biomarkers
Pneumonia
Multiple Organ Failure

Interventions: Drug: Clarithromycin
Drug: Water for injection

First Posted Date: 2017-11-17

Last Posted Date: 2020-12-22

Lead Sponsor: Hellenic Institute for the Study of Sepsis

Target Recruit Count: 110

Registration Number: NCT03345992

Locations: 🇧🇪
Intensive Care Unit, Saint-Pierre University Hospital, Brussels, Belgium
🇧🇪
Intensive Care Unit, Brugmann University Hospital, Brussels, Belgium
🇧🇪
Intensive Care Unit, Erasme University Hospital, Brussels, Belgium

and more 9 locations

A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis

Phase 2

Completed

Conditions: Sepsis
Macrophage Activation Syndrome

Interventions: Drug: Placebo
Drug: Recombinant human interferon-gamma
Drug: Anakinra

First Posted Date: 2017-11-06

Last Posted Date: 2020-07-29

Lead Sponsor: Hellenic Institute for the Study of Sepsis

Target Recruit Count: 36

Registration Number: NCT03332225

Locations: 🇬🇷
2nd Department of Critical Care Medicine, Athens, Haidari, Greece
🇬🇷
4th Department of Internal Medicine, Athens, Haidari, Greece
🇬🇷
Intensive Care Unit, Ioannina University Hospital, Ioánnina, Ioannina, Greece

and more 10 locations

A Clinical Trial of Procalcitonin-guided Antimicrobial Therapy in Sepsis

Not Applicable

Completed

Conditions: Sepsis

Interventions: Diagnostic Test: Procalcitonin measurement

First Posted Date: 2017-11-06

Last Posted Date: 2019-12-17

Lead Sponsor: Hellenic Institute for the Study of Sepsis

Target Recruit Count: 266

Registration Number: NCT03333304

Locations: 🇬🇷
1st Department of Internal Medicine, General Hospital of Athens "G. Gennimatas", Athens, Greece
🇬🇷
3rd Department of Internal Medicine, Sotiria Athens General Hospital, Athens, Greece
🇬🇷
4th Department of Internal Medicine, Attikon University Hospital, Athens, Greece

and more 4 locations

Bacillus Calmette-guérin Vaccination to Prevent Infections of the Elderly

Phase 4

Completed

Conditions: Infection
Hospitalization
Mortality

Interventions: Biological: Vaccination
Biological: Placebo

First Posted Date: 2017-09-28

Last Posted Date: 2021-01-11

Lead Sponsor: Hellenic Institute for the Study of Sepsis

Target Recruit Count: 200

Registration Number: NCT03296423

Locations: 🇬🇷
4th Department of Internal Medicine, ATTIKON University Hospital, Athens, Attiki, Greece

Heparin Binding Protein in Early Sepsis Diagnosis

Not Applicable

Completed

Conditions: Sepsis
Infection

Interventions: Diagnostic Test: Biomarker

First Posted Date: 2017-09-28

Last Posted Date: 2018-10-23

Lead Sponsor: Hellenic Institute for the Study of Sepsis

Target Recruit Count: 400

Registration Number: NCT03295825

Locations: 🇬🇷
Nafplion General Hospital, Náfplio, Argos, Greece
🇬🇷
4th Department of Internal Medicine, ATTIKON University Hospital, Athens, Attiki, Greece
🇬🇷
Department of Internal Medicine, Chalkida General Hospital, Chalkida, Greece

and more 3 locations

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